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Iruplinalkib (WX-0593) Versus Crizotinib in ALK TKI-Naive Locally Advanced or Metastatic ALK-Positive NSCLC: Interim Analysis of a Randomized, Open-Label, Phase 3 Study (INSPIRE)

Journal of thoracic oncology, 2024-06, Vol.19 (6), p.912-927

2024

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Efficacy and safety of iruplinalkib (WX-0593) in ALK-positive crizotinib-resistant advanced non-small cell lung cancer patients: a single-arm, multicenter phase II study (INTELLECT)

BMC medicine, 2023-02, Vol.21 (1), p.72-72, Article 72

2023

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IRUNet for medical image segmentation

Expert systems with applications, 2022-04, Vol.191, p.116399, Article 116399

2022

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Comparative genomics reveals insights into the potential of Lysinibacillus irui as a plant growth promoter

Applied microbiology and biotechnology, 2024-12, Vol.108 (1), p.370

2024

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Japan's initiative on rare and undiagnosed diseases (IRUD): towards an end to the diagnostic odyssey

European journal of human genetics : EJHG, 2017-09, Vol.25 (9), p.1025-1028

2017

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Chemoradiotherapy (CRT) Combined with Consolidative Iruplinalkib for ALK/ROS1+ Unresectable Non-Small Cell Lung Cancer (NSCLC): ALK+ Cohort Results from Part 1 of the INNOVATION Study

International journal of radiation oncology, biology, physics, 2024-10, Vol.120 (2), p.e76-e77

2024

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Metamorphic P-T-t evolution of ultrahigh-temperature granulite facies metapelites from the Lundazi terrane, Irumide Belt, Eastern Zambia

Precambrian research, 2024-02, Vol.401, p.107271, Article 107271

2024

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Iruka Eliminates Dysfunctional Argonaute by Selective Ubiquitination of Its Empty State

Molecular cell, 2019-01, Vol.73 (1), p.119-129.e5

2019

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Islamischer Religionsunterricht (IRU) in Deutschland im Spannungsfeld von Religion, Bildung, Politik und Gesellschaft

Zeitschrift für Religion, Gesellschaft und Politik, 2023, Vol.7 (1), p.367-393

2023

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Lysinibacillus irui sp. nov., isolated from Iru, fermented African locust beans

International journal of systematic and evolutionary microbiology, 2023-11, Vol.73 (11)

2023

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Subduction to accretion in the southern Irumide Belt: Perspective from geochronology and petrology of granulites and charnockites in NW Mozambique

Precambrian research, 2023-10, Vol.397, p.107190, Article 107190

2023

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Iruplinalkib: First Approval

Drugs (New York, N.Y.), 2023-12, Vol.83 (18), p.1717-1721

Keam, Susan J.

2023

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Iruplinalkib (WX‑0593), a novel ALK/ROS1 inhibitor, overcomes crizotinib resistance in preclinical models for non-small cell lung cancer

Investigational new drugs, 2023-04, Vol.41 (2), p.254-266

2023

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Pharmacokinetics, metabolism, excretion and safety of iruplinalkib (WX-0593), a novel ALK inhibitor, in healthy subjects: a phase I human radiolabeled mass balance study

Expert opinion on investigational drugs, 2024, Vol.33 (1), p.63-72

2024

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556P Results from the phase I study on efficacy and safety of iruplinalkib (WX-0593) for anaplastic lymphoma kinase (ALK)-positive advanced non-small cell lung cancer (NSCLC) patients who received prior second-generation ALK tyrosine kinase inhibitors (TKIs)

Annals of oncology, 2023-11, Vol.34, p.S1686-S1687

2023

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380P An epidemiological analysis on the prevalence of oral cancer and its awareness among Irula tribes of South India

Annals of oncology, 2023-11, Vol.34, p.S1616

Francis, D.L.

2023

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Physiological and morphological responses of ‘Irukandji’ polyps to thermal and osmotic conditions: consequences for niche profiling

Hydrobiologia, 2023-03, Vol.850 (5), p.1207-1216

2023

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Environmental drivers of the occurrence and abundance of the Irukandji jellyfish (Carukia barnesi)

PloS one, 2022-08, Vol.17 (8), p.e0272359-e0272359

2022

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U-Pb and Lu-Hf zircon data of the grenvilian arc-related Zâmbué, Fíngoè and Cazula supracrustal complexes, Southern Irumide Belt, NW Mozambique

Precambrian research, 2022-10, Vol.381, p.106860, Article 106860

2022

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Fast and high spatially resolved multielemental mapping of otoliths using IR&UV-femtosecond laser ablation-ICP-TOFMS

Journal of analytical atomic spectrometry, 2024-02, Vol.39 (2), p.61-69

2024

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Iruplinalkib (WX-0593), the Seventh ALK Tyrosine Kinase Inhibitor Approved in People's Republic of China With More to Come

Journal of thoracic oncology, 2024-06, Vol.19 (6), p.855-857

2024

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Developing an International Registry for Uterus Transplantation (IRUTx): Promises and Challenges

Human reproduction (Oxford), 2020-12, Vol.35 (12), p.2643-2649

2020

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The Effect of IRubus idaeus/I Polyphenols Extract in Induced Endometriosis in Rats

Molecules (Basel, Switzerland), 2024-02, Vol.29 (4)

2024

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A phase II trial of ALK/ROS1 tyrosine kinase inhibitor WX-0593 (iruplinalkib) in ALK -positive and crizotinib-resistant advanced non–small cell lung cancer

Journal of clinical oncology, 2022-06, Vol.40 (16_suppl), p.9073-9073

2022

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Revisiting methods to characterize bioelectrochemical systems: The influence of uncompensated resistance (iRu-drop), double layer capacitance, and junction potential

Journal of power sources, 2017, Vol.356, p.408-418

2017

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Iruplinalkib (WX-0593) Versus Crizotinib in ALK TKI-Naive Locally Advanced or Metastatic ALK-Positive NSCLC: Interim Analysis of a Randomized, Open-Label, Phase 3 Study (INSPIRE)

Efficacy and safety of iruplinalkib (WX-0593) in ALK-positive crizotinib-resistant advanced non-small cell lung cancer patients: a single-arm, multicenter phase II study (INTELLECT)

IRUNet for medical image segmentation

Comparative genomics reveals insights into the potential of Lysinibacillus irui as a plant growth promoter

Japan's initiative on rare and undiagnosed diseases (IRUD): towards an end to the diagnostic odyssey

Chemoradiotherapy (CRT) Combined with Consolidative Iruplinalkib for ALK/ROS1+ Unresectable Non-Small Cell Lung Cancer (NSCLC): ALK+ Cohort Results from Part 1 of the INNOVATION Study

Metamorphic P-T-t evolution of ultrahigh-temperature granulite facies metapelites from the Lundazi terrane, Irumide Belt, Eastern Zambia

Iruka Eliminates Dysfunctional Argonaute by Selective Ubiquitination of Its Empty State

Islamischer Religionsunterricht (IRU) in Deutschland im Spannungsfeld von Religion, Bildung, Politik und Gesellschaft

Lysinibacillus irui sp. nov., isolated from Iru, fermented African locust beans

Subduction to accretion in the southern Irumide Belt: Perspective from geochronology and petrology of granulites and charnockites in NW Mozambique

Iruplinalkib: First Approval

Iruplinalkib (WX‑0593), a novel ALK/ROS1 inhibitor, overcomes crizotinib resistance in preclinical models for non-small cell lung cancer

Pharmacokinetics, metabolism, excretion and safety of iruplinalkib (WX-0593), a novel ALK inhibitor, in healthy subjects: a phase I human radiolabeled mass balance study

556P Results from the phase I study on efficacy and safety of iruplinalkib (WX-0593) for anaplastic lymphoma kinase (ALK)-positive advanced non-small cell lung cancer (NSCLC) patients who received prior second-generation ALK tyrosine kinase inhibitors (TKIs)

380P An epidemiological analysis on the prevalence of oral cancer and its awareness among Irula tribes of South India

Physiological and morphological responses of ‘Irukandji’ polyps to thermal and osmotic conditions: consequences for niche profiling

Environmental drivers of the occurrence and abundance of the Irukandji jellyfish (Carukia barnesi)

U-Pb and Lu-Hf zircon data of the grenvilian arc-related Zâmbué, Fíngoè and Cazula supracrustal complexes, Southern Irumide Belt, NW Mozambique

Fast and high spatially resolved multielemental mapping of otoliths using IR&UV-femtosecond laser ablation-ICP-TOFMS

Iruplinalkib (WX-0593), the Seventh ALK Tyrosine Kinase Inhibitor Approved in People's Republic of China With More to Come

Developing an International Registry for Uterus Transplantation (IRUTx): Promises and Challenges

The Effect of IRubus idaeus/I Polyphenols Extract in Induced Endometriosis in Rats

A phase II trial of ALK/ROS1 tyrosine kinase inhibitor WX-0593 (iruplinalkib) in ALK -positive and crizotinib-resistant advanced non–small cell lung cancer

Revisiting methods to characterize bioelectrochemical systems: The influence of uncompensated resistance (iRu-drop), double layer capacitance, and junction potential

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