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Polycomb silencers control cell fate, development and cancer

Nature reviews. Cancer, 2006-11, Vol.6 (11), p.846-856

2006

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Chromatin Position Effects Assayed by Thousands of Reporters Integrated in Parallel

Cell, 2013-08, Vol.154 (4), p.914-927

2013

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Multiplexed Cas9 targeting reveals genomic location effects and gRNA-based staggered breaks influencing mutation efficiency

Nature communications, 2019-04, Vol.10 (1), p.1598-14, Article 1598

2019

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Functional Crosstalk between Bmi1 and MLL/Hoxa9 Axis in Establishment of Normal Hematopoietic and Leukemic Stem Cells

Cell stem cell, 2011-06, Vol.8 (6), p.649-662

2011

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Prolonged Ezh2 Depletion in Glioblastoma Causes a Robust Switch in Cell Fate Resulting in Tumor Progression

Cell reports (Cambridge), 2015-01, Vol.10 (3), p.383-397

2015

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Stem cell regulation by polycomb repressors: postponing commitment

Current opinion in cell biology, 2008-04, Vol.20 (2), p.201-207

2008

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Molecular Maps of the Reorganization of Genome-Nuclear Lamina Interactions during Differentiation

Molecular cell, 2010-05, Vol.38 (4), p.603-613

2010

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In Vivo RNAi Screen for BMI1 Targets Identifies TGF-β/BMP-ER Stress Pathways as Key Regulators of Neural- and Malignant Glioma-Stem Cell Homeostasis

Cancer cell, 2013-05, Vol.23 (5), p.660-676

2013

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Functional anatomy of polycomb and trithorax chromatin landscapes in Drosophila embryos

PLoS biology, 2009-01, Vol.7 (1), p.e13-e1000013

2009

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Epigenetics and cancer

Genes & development, 2004-10, Vol.18 (19), p.2315-2335

2004

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BMI1 Is Recruited to DNA Breaks and Contributes to DNA Damage-Induced H2A Ubiquitination and Repair

Molecular and Cellular Biology, 2011-05, Vol.31 (10), p.1972-1982

2011

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Interactions among Polycomb domains are guided by chromosome architecture

PLoS genetics, 2011-03, Vol.7 (3), p.e1001343-e1001343

2011

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TRIM28 Is an Epigenetic Barrier to Induced Pluripotent Stem Cell Reprogramming

Stem cells (Dayton, Ohio), 2017-01, Vol.35 (1), p.147-157

2017

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Structure and E3-ligase activity of the Ring-Ring complex of Polycomb proteins Bmi1 and Ring1b

The EMBO journal, 2006-06, Vol.25 (11), p.2465-2474

2006

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Combined deletion of Bap1, Nf2, and Cdkn2ab causes rapid onset of malignant mesothelioma in mice

The Journal of experimental medicine, 2020-06, Vol.217 (6)

2020

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PRC1 coordinates timing of sexual differentiation of female primordial germ cells

Nature (London), 2013-03, Vol.495 (7440), p.236-240

2013

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Genome-wide profiling of PRC1 and PRC2 Polycomb chromatin binding in Drosophila melanogaster

Nature genetics, 2006-06, Vol.38 (6), p.694-699

2006

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Deletion of Polycomb Repressive Complex 2 From Mouse Intestine Causes Loss of Stem Cells

Gastroenterology (New York, N.Y. 1943), 2016-10, Vol.151 (4), p.684-697.e12

2016

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Chromatin landscapes of retroviral and transposon integration profiles

PLoS genetics, 2014-04, Vol.10 (4), p.e1004250

2014

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Polycomb Group Proteins Ezh2 and Rnf2 Direct Genomic Contraction and Imprinted Repression in Early Mouse Embryos

Developmental cell, 2008-11, Vol.15 (5), p.668-679

2008

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The many faces of ubiquitinated histone H2A: insights from the DUBs

Cell division, 2008-04, Vol.3 (1), p.8-8, Article 8

2008

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A genome-wide enrichment screen identifies NUMA1-loss as a resistance mechanism against mitotic cell-death induced by BMI1 inhibition

PloS one, 2020-04, Vol.15 (4), p.e0227592

2020

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The chromodomain helicase Chd4 is required for Polycomb-mediated inhibition of astroglial differentiation

The EMBO journal, 2013-05, Vol.32 (11), p.1598-1612

2013

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Enhanced Self-Renewal of Hematopoietic Stem Cells Mediated by the Polycomb Gene Product Bmi-1

Immunity (Cambridge, Mass.), 2004-12, Vol.21 (6), p.843-851

2004

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Polycomb function during oogenesis is required for mouse embryonic development

Genes & development, 2012-05, Vol.26 (9), p.920-932

2012

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Polycomb silencers control cell fate, development and cancer

Chromatin Position Effects Assayed by Thousands of Reporters Integrated in Parallel

Multiplexed Cas9 targeting reveals genomic location effects and gRNA-based staggered breaks influencing mutation efficiency

Functional Crosstalk between Bmi1 and MLL/Hoxa9 Axis in Establishment of Normal Hematopoietic and Leukemic Stem Cells

Prolonged Ezh2 Depletion in Glioblastoma Causes a Robust Switch in Cell Fate Resulting in Tumor Progression

Stem cell regulation by polycomb repressors: postponing commitment

Molecular Maps of the Reorganization of Genome-Nuclear Lamina Interactions during Differentiation

In Vivo RNAi Screen for BMI1 Targets Identifies TGF-β/BMP-ER Stress Pathways as Key Regulators of Neural- and Malignant Glioma-Stem Cell Homeostasis

Functional anatomy of polycomb and trithorax chromatin landscapes in Drosophila embryos

Epigenetics and cancer

BMI1 Is Recruited to DNA Breaks and Contributes to DNA Damage-Induced H2A Ubiquitination and Repair

Interactions among Polycomb domains are guided by chromosome architecture

TRIM28 Is an Epigenetic Barrier to Induced Pluripotent Stem Cell Reprogramming

Structure and E3-ligase activity of the Ring-Ring complex of Polycomb proteins Bmi1 and Ring1b

Combined deletion of Bap1, Nf2, and Cdkn2ab causes rapid onset of malignant mesothelioma in mice

PRC1 coordinates timing of sexual differentiation of female primordial germ cells

Genome-wide profiling of PRC1 and PRC2 Polycomb chromatin binding in Drosophila melanogaster

Deletion of Polycomb Repressive Complex 2 From Mouse Intestine Causes Loss of Stem Cells

Chromatin landscapes of retroviral and transposon integration profiles

Polycomb Group Proteins Ezh2 and Rnf2 Direct Genomic Contraction and Imprinted Repression in Early Mouse Embryos

The many faces of ubiquitinated histone H2A: insights from the DUBs

A genome-wide enrichment screen identifies NUMA1-loss as a resistance mechanism against mitotic cell-death induced by BMI1 inhibition

The chromodomain helicase Chd4 is required for Polycomb-mediated inhibition of astroglial differentiation

Enhanced Self-Renewal of Hematopoietic Stem Cells Mediated by the Polycomb Gene Product Bmi-1

Polycomb function during oogenesis is required for mouse embryonic development

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