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Discovery of a Potent, Orally Available, and Isoform-Selective Retinoic Acid β2 Receptor Agonist

Journal of medicinal chemistry, 2005-12, Vol.48 (24), p.7517-7519

2005

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Constitutively Active Mutants of the Histamine H1 Receptor Suggest a Conserved Hydrophobic Asparagine-Cage That Constrains the Activation of Class A G Protein-Coupled Receptors

Molecular pharmacology, 2008-01, Vol.73 (1), p.94

2008

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Pimavanserin, a selective serotonin (5-HT)2A-inverse agonist, enhances the efficacy and safety of risperidone, 2mg/day, but does not enhance efficacy of haloperidol, 2mg/day: Comparison with reference dose risperidone, 6mg/day

Schizophrenia research, 2012-11, Vol.141 (2-3), p.144-152

2012

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1 The Chemistry and Biochemistry of C-Nucleosides and C-Arylglycosides

Progress in Medicinal Chemistry, 1985, Vol.22, p.1-65

1985

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Analysis of molecular determinants of affinity and relative efficacy of a series of R ‐ and S ‐2‐(dipropylamino)tetralins at the 5‐HT 1A serotonin receptor

British journal of pharmacology, 2009-01, Vol.138 (6), p.1129-1139

2009

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8-Hydroxy-2-(dipropylamino)tetralin, a new centrally acting 5-hydroxytryptamine receptor agonist

Journal of medicinal chemistry, 1981-08, Vol.24 (8), p.921-923

1981

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Synthesis of 1,2,4-Oxadiazole-, 1,3,4-Oxadiazole-, and 1,2,4-Triazole-Derived Dipeptidomimetics

Journal of organic chemistry, 1995-05, Vol.60 (10), p.3112-3120

1995

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(R)- and (S)-8-acetyl-2-(dipropylamino)tetralin (LY-41) : two novel 5-HT1A receptor agonists

European journal of pharmacology, 1993-01, Vol.231 (1), p.69-76

1993

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Discovery of a potent, orally available, and isoform-selective retinoic acid beta2 receptor agonist

Journal of medicinal chemistry, 2005-12, Vol.48 (24), p.7517-7519

2005

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Pharmacology of polymorphic variants of the human 5-HT 1A receptor

Biochemical pharmacology, 2004, Vol.67 (3), p.479-490

2004

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Syntheses of 5-, 7-, and 8-methoxy-3-methyl-2-tetralones

Journal of organic chemistry, 1986-12, Vol.51 (26), p.5252-5258

1986

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Atropisomeric Derivatives of 2‘,6‘-Disubstituted ( R )-11-Phenylaporphine: Selective Serotonin 5-HT 7 Receptor Antagonists

Journal of medicinal chemistry, 2001-04, Vol.44 (9), p.1337-1340

2001

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Molecular basis for the binding of 2-aminotetralins to human dopamine D2A and D3 receptors

Molecular pharmacology, 1994-08, Vol.46 (2), p.299

1994

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Discovery of an ectopic activation site on the M(1) muscarinic receptor

Molecular pharmacology, 2002-06, Vol.61 (6), p.1297-1302

2002

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Discovery of an Ectopic Activation Site on the M1Muscarinic Receptor

Molecular pharmacology, 2002-06, Vol.61 (6), p.1297

2002

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Intramolecular Transfer of CO from (.eta.6-arene)Cr(CO)3 Complexes in Stille-Type Palladium-Catalyzed Cross-Coupling Reactions

Organometallics, 1995-08, Vol.14 (8), p.3897-3900

1995

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Derivatives of 2-arylcyclopropylamine: Synthesis and interactions with 5-HT 1A receptors

Bioorganic & medicinal chemistry letters, 1996, Vol.6 (4), p.415-420

1996

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Interactions of ligands with active and inactive conformations of the dopamine D2 receptor

European journal of pharmacology, 1998-04, Vol.346 (2-3), p.299-307

1998

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Derivatives of cis-2-Amino-8-hydroxy-1-methyltetralin: Mixed 5-HT1A-Receptor Agonists and Dopamine D2-Receptor Antagonists

Journal of medicinal chemistry, 1995-01, Vol.38 (1), p.150-160

1995

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Stereoselective palladium-catalyzed cyclopropanation of α,β-unsaturated carboxylic acids derivatized with oppolzer's sultam

Tetrahedron letters, 1991-09, Vol.32 (40), p.5625-5628

1991

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Regio- and Stereoselective Reactions of 17-Phenyl-18,19,20-trinorprostaglandin F2 α Isopropyl Ester

Journal of organic chemistry, 1996-06, Vol.61 (12), p.4028-4034

1996

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Novel heterocycles derived from 3-acyloxy- and 3-acetamidoquinuclidines

Journal of heterocyclic chemistry, 1994-11, Vol.31 (6), p.1497-1501

1994

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Novel derivatives of 3-(dipropylamino)chroman. Interactions with 5-HT 1A and D 2A receptors

Bioorganic & medicinal chemistry letters, 1999, Vol.9 (11), p.1583-1586

1999

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(R)-11-Hydroxy- and (R)-11-Hydroxy-10-methylaporphine: Synthesis, Pharmacology, and Modeling of D2A and 5-HT1A Receptor Interactions

Journal of medicinal chemistry, 1995-02, Vol.38 (4), p.647-658

1995

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Palladium catalyzed syntheses of phenyl-substittuted pgf2α analogues: potential antigluaucoma agents

Bioorganic & medicinal chemistry letters, 1993-02, Vol.3 (2), p.241-244

1993

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Discovery of a Potent, Orally Available, and Isoform-Selective Retinoic Acid β2 Receptor Agonist

Constitutively Active Mutants of the Histamine H1 Receptor Suggest a Conserved Hydrophobic Asparagine-Cage That Constrains the Activation of Class A G Protein-Coupled Receptors

Pimavanserin, a selective serotonin (5-HT)2A-inverse agonist, enhances the efficacy and safety of risperidone, 2mg/day, but does not enhance efficacy of haloperidol, 2mg/day: Comparison with reference dose risperidone, 6mg/day

1 The Chemistry and Biochemistry of C-Nucleosides and C-Arylglycosides

Analysis of molecular determinants of affinity and relative efficacy of a series of R ‐ and S ‐2‐(dipropylamino)tetralins at the 5‐HT 1A serotonin receptor

8-Hydroxy-2-(dipropylamino)tetralin, a new centrally acting 5-hydroxytryptamine receptor agonist

Synthesis of 1,2,4-Oxadiazole-, 1,3,4-Oxadiazole-, and 1,2,4-Triazole-Derived Dipeptidomimetics

(R)- and (S)-8-acetyl-2-(dipropylamino)tetralin (LY-41) : two novel 5-HT1A receptor agonists

Discovery of a potent, orally available, and isoform-selective retinoic acid beta2 receptor agonist

Pharmacology of polymorphic variants of the human 5-HT 1A receptor

Syntheses of 5-, 7-, and 8-methoxy-3-methyl-2-tetralones

Atropisomeric Derivatives of 2‘,6‘-Disubstituted ( R )-11-Phenylaporphine: Selective Serotonin 5-HT 7 Receptor Antagonists

Molecular basis for the binding of 2-aminotetralins to human dopamine D2A and D3 receptors

Discovery of an ectopic activation site on the M(1) muscarinic receptor

Discovery of an Ectopic Activation Site on the M1Muscarinic Receptor

Intramolecular Transfer of CO from (.eta.6-arene)Cr(CO)3 Complexes in Stille-Type Palladium-Catalyzed Cross-Coupling Reactions

Derivatives of 2-arylcyclopropylamine: Synthesis and interactions with 5-HT 1A receptors

Interactions of ligands with active and inactive conformations of the dopamine D2 receptor

Derivatives of cis-2-Amino-8-hydroxy-1-methyltetralin: Mixed 5-HT1A-Receptor Agonists and Dopamine D2-Receptor Antagonists

Stereoselective palladium-catalyzed cyclopropanation of α,β-unsaturated carboxylic acids derivatized with oppolzer's sultam

Regio- and Stereoselective Reactions of 17-Phenyl-18,19,20-trinorprostaglandin F2 α Isopropyl Ester

Novel heterocycles derived from 3-acyloxy- and 3-acetamidoquinuclidines

Novel derivatives of 3-(dipropylamino)chroman. Interactions with 5-HT 1A and D 2A receptors

(R)-11-Hydroxy- and (R)-11-Hydroxy-10-methylaporphine: Synthesis, Pharmacology, and Modeling of D2A and 5-HT1A Receptor Interactions

Palladium catalyzed syntheses of phenyl-substittuted pgf2α analogues: potential antigluaucoma agents

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