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Structure-activity relationship studies of four novel 4-aminopyridine K + channel blockers

Scientific reports, 2020-01, Vol.10 (1), p.52-52, Article 52

2020

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Ion channels as drug targets in central nervous system disorders

Current medicinal chemistry, 2013-04, Vol.20 (10), p.1241

2013

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Effect of nitric oxide-cyclic GMP-K + channel pathway blockers, naloxone and metformin, on the antinociception induced by the diuretic pamabrom

Canadian journal of physiology and pharmacology, 2023-01, Vol.101 (1), p.41

2023

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Citral inhibits the nociception in the rat formalin test: effect of metformin and blockers of opioid receptor and the NO-cGMP-K + channel pathway

Canadian journal of physiology and pharmacology, 2022-04, Vol.100 (4), p.306

2022

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Atrial-selective K + channel blockers: potential antiarrhythmic drugs in atrial fibrillation?

Canadian journal of physiology and pharmacology, 2017-11, Vol.95 (11), p.1313

Ravens, Ursula

2017

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Prolonged immunomodulation in inflammatory arthritis using the selective Kv1.3 channel blocker HsTX1[R14A] and its PEGylated analog

Clinical immunology (Orlando, Fla.), 2017-07, Vol.180, p.45-57

2017

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Combining mKate2-Kv1.3 Channel and Atto488-Hongotoxin for the Studies of Peptide Pore Blockers on Living Eukaryotic Cells

Toxins, 2022-12, Vol.14 (12), p.858

2022

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Antidepressive effect of an inward rectifier K+ channel blocker peptide, tertiapin-RQ

PloS one, 2020-11, Vol.15 (11), p.e0233815-e0233815

2020

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Insight on the interaction between the scorpion toxin blocker Discrepin on potassium voltage-gated channel Kv4.3 by molecular dynamics simulations

Journal of biomolecular structure & dynamics, 2023-09, Vol.41 (13), p.6272-6281

2023

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Beyond hemostasis: a snake venom serine protease with potassium channel blocking and potential antitumor activities

Scientific reports, 2020-03, Vol.10 (1), p.4476, Article 4476

2020

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Alternative Targets for Modulators of Mitochondrial Potassium Channels

Molecules (Basel, Switzerland), 2022-01, Vol.27 (1), p.299

2022

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A potent and selective peptide blocker of the Kv1.3 channel: prediction from free-energy simulations and experimental confirmation

PloS one, 2013-11, Vol.8 (11), p.e78712

2013

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Studies of Conorfamide-Sr3 on Human Voltage-Gated Kv1 Potassium Channel Subtypes

Marine drugs, 2020-08, Vol.18 (8), p.425

2020

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Revealing the structural basis of action of hERG potassium channel activators and blockers

The Journal of physiology, 2010-09, Vol.588 (Pt 17), p.3157-3167

2010

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Chronic Stress Causes Amygdala Hyperexcitability in Rodents

Biological psychiatry (1969), 2010-06, Vol.67 (12), p.1128-1136

2010

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High-throughput electrophysiological assays for voltage gated ion channels using SyncroPatch 768PE

PloS one, 2017-07, Vol.12 (7), p.e0180154-e0180154

2017

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Suppression of KCNQ/M (Kv7) potassium channels in dorsal root ganglion neurons contributes to the development of bone cancer pain in a rat model

Pain (Amsterdam), 2013-03, Vol.154 (3), p.434-448

2013

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The Study on the hERG Blocker Prediction Using Chemical Fingerprint Analysis

Molecules (Basel, Switzerland), 2020-06, Vol.25 (11), p.2615

2020

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Electrocardiographic Biomarkers for Detection of Drug-Induced Late Sodium Current Block

PloS one, 2016-12, Vol.11 (12), p.e0163619-e0163619

2016

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A potent and Kv1.3-selective analogue of the scorpion toxin HsTX1 as a potential therapeutic for autoimmune diseases

Scientific reports, 2014-03, Vol.4 (1), p.4509, Article 4509

2014

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Pungent agents from Szechuan peppers excite sensory neurons by inhibiting two-pore potassium channels

Nature neuroscience, 2008-07, Vol.11 (7), p.772-779

2008

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Zerumbone-Induced Analgesia Modulated via Potassium Channels and Opioid Receptors in Chronic Constriction Injury-Induced Neuropathic Pain

Molecules (Basel, Switzerland), 2020-08, Vol.25 (17), p.3880

2020

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Correlation between potassium channel expression and sensitivity to drug-induced cell death in tumor cell lines

Current pharmaceutical design, 2014-01, Vol.20 (2), p.189

2014

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Emerging roles for two-pore-domain potassium channels and their potential therapeutic impact

Trends in pharmacological sciences (Regular ed.), 2008-11, Vol.29 (11), p.566-575

2008

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Ivabradine prolongs phase 3 of cardiac repolarization and blocks the hERG1 (KCNH2) current over a concentration-range overlapping with that required to block HCN4

Journal of molecular and cellular cardiology, 2015-08, Vol.85, p.71-78

2015

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Structure-activity relationship studies of four novel 4-aminopyridine K + channel blockers

Ion channels as drug targets in central nervous system disorders

Effect of nitric oxide-cyclic GMP-K + channel pathway blockers, naloxone and metformin, on the antinociception induced by the diuretic pamabrom

Citral inhibits the nociception in the rat formalin test: effect of metformin and blockers of opioid receptor and the NO-cGMP-K + channel pathway

Atrial-selective K + channel blockers: potential antiarrhythmic drugs in atrial fibrillation?

Prolonged immunomodulation in inflammatory arthritis using the selective Kv1.3 channel blocker HsTX1[R14A] and its PEGylated analog

Combining mKate2-Kv1.3 Channel and Atto488-Hongotoxin for the Studies of Peptide Pore Blockers on Living Eukaryotic Cells

Antidepressive effect of an inward rectifier K+ channel blocker peptide, tertiapin-RQ

Insight on the interaction between the scorpion toxin blocker Discrepin on potassium voltage-gated channel Kv4.3 by molecular dynamics simulations

Beyond hemostasis: a snake venom serine protease with potassium channel blocking and potential antitumor activities

Alternative Targets for Modulators of Mitochondrial Potassium Channels

A potent and selective peptide blocker of the Kv1.3 channel: prediction from free-energy simulations and experimental confirmation

Studies of Conorfamide-Sr3 on Human Voltage-Gated Kv1 Potassium Channel Subtypes

Revealing the structural basis of action of hERG potassium channel activators and blockers

Chronic Stress Causes Amygdala Hyperexcitability in Rodents

High-throughput electrophysiological assays for voltage gated ion channels using SyncroPatch 768PE

Suppression of KCNQ/M (Kv7) potassium channels in dorsal root ganglion neurons contributes to the development of bone cancer pain in a rat model

The Study on the hERG Blocker Prediction Using Chemical Fingerprint Analysis

Electrocardiographic Biomarkers for Detection of Drug-Induced Late Sodium Current Block

A potent and Kv1.3-selective analogue of the scorpion toxin HsTX1 as a potential therapeutic for autoimmune diseases

Pungent agents from Szechuan peppers excite sensory neurons by inhibiting two-pore potassium channels

Zerumbone-Induced Analgesia Modulated via Potassium Channels and Opioid Receptors in Chronic Constriction Injury-Induced Neuropathic Pain

Correlation between potassium channel expression and sensitivity to drug-induced cell death in tumor cell lines

Emerging roles for two-pore-domain potassium channels and their potential therapeutic impact

Ivabradine prolongs phase 3 of cardiac repolarization and blocks the hERG1 (KCNH2) current over a concentration-range overlapping with that required to block HCN4

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