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Inhibition of angiotensin convertin enzyme (ACE) activity by the anthocyanins delphinidin- and cyanidin-3- O-sambubiosides from Hibiscus sabdariffa

Journal of ethnopharmacology, 2010-01, Vol.127 (1), p.7-10

2010

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Investigation on the metabolic characteristics of isobavachin in Psoralea corylifolia L. (Bu‐gu‐zhi) and its potential inhibition against human cytochrome P450s and UDP‐glucuronosyltransferases

Journal of pharmacy and pharmacology, 2020-12, Vol.72 (12), p.1865-1878

2020

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Inhibitory Effects of Selected Antituberculosis Drugs on Common Human Hepatic Cytochrome P450 and UDP-glucuronosyltransferase Enzymes

Drug metabolism and disposition, 2017-09, Vol.45 (9), p.1035-1043

2017

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What is the contribution of human FMO3 in the N-oxygenation of selected therapeutic drugs and drugs of abuse?

Toxicology letters, 2016-09, Vol.258, p.55-70

2016

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(99m)Tc-labeled gastrins of varying peptide chain length: Distinct impact of NEP/ACE-inhibition on stability and tumor uptake in mice

Nuclear medicine and biology, 2016-06, Vol.43 (6), p.347-354

2016

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Comprehensive Evaluation for Substrate Selectivity of Cynomolgus Monkey Cytochrome P450 2C9, a New Efavirenz Oxidase

Drug metabolism and disposition, 2015-07, Vol.43 (7), p.1119-1122

2015

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Residues Determining the Binding Specificity of Uncompetitive Inhibitors to Tissue‐Nonspecific Alkaline Phosphatase

Journal of bone and mineral research, 2004-11, Vol.19 (11), p.1862-1872

2004

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Mechanism of Inhibition of Ebola Virus RNA-Dependent RNA Polymerase by Remdesivir

Viruses, 2019-04, Vol.11 (4), p.326

2019

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Identification of bla(IMP-22) in Pseudomonas spp. in urban wastewater and nosocomial environments: biochemical characterization of a new IMP metallo-enzyme variant and its genetic location

Journal of antimicrobial chemotherapy, 2009-05, Vol.63 (5), p.901

2009

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Challenges in the Discovery of Indoleamine 2,3-Dioxygenase 1 (IDO1) Inhibitors

Journal of medicinal chemistry, 2015-12, Vol.58 (24), p.9421-9437

2015

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Angiotensin-Converting Enzyme (ACE) Dimerization Is the Initial Step in the ACE Inhibitor-Induced ACE Signaling Cascade in Endothelial Cells

Molecular pharmacology, 2006-05, Vol.69 (5), p.1725-1732

2006

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Structural Basis of Metallo-β-Lactamase Inhibition by Captopril Stereoisomers

Antimicrobial agents and chemotherapy, 2016-01, Vol.60 (1), p.142-150

2016

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Kojic acid–natural product conjugates as mushroom tyrosinase inhibitors

European journal of medicinal chemistry, 2020-09, Vol.201, p.112480, Article 112480

2020

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Expression, Purification, Characterization, and in Vivo Targeting of Trypanosome CTP Synthetase for Treatment of African Sleeping Sickness

The Journal of biological chemistry, 2007-04, Vol.282 (16), p.11858-11865

2007

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IC50-to-Ki: a web-based tool for converting IC50 to Ki values for inhibitors of enzyme activity and ligand binding

Nucleic acids research, 2009-07, Vol.37 (Web Server issue), p.W441-W445

2009

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Selective Sirt2 inhibition by ligand-induced rearrangement of the active site

Nature communications, 2015-02, Vol.6 (1), p.6263-6263, Article 6263

2015

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Enzymes and nanoparticles: Modulation of enzymatic activity via nanoparticles

International journal of biological macromolecules, 2018-10, Vol.118 (Pt B), p.1833-1847

2018

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Synthesis and Multitarget Biological Profiling of a Novel Family of Rhein Derivatives As Disease-Modifying Anti-Alzheimer Agents

Journal of medicinal chemistry, 2014-03, Vol.57 (6), p.2549-2567

2014

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Identification of the human cytochrome P450 enzymes involved in the two oxidative steps in the bioactivation of clopidogrel to its pharmacologically active metabolite

Drug metabolism and disposition, 2010-01, Vol.38 (1), p.92-99

2010

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Comparative Evaluation of Quercetin, Isoquercetin and Rutin as Inhibitors of α-Glucosidase

Journal of agricultural and food chemistry, 2009-12, Vol.57 (24), p.11463-11468

2009

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Synthesis of chalcone-imide derivatives and investigation of their anticancer and antimicrobial activities, carbonic anhydrase and acetylcholinesterase enzymes inhibition profiles

Archives of physiology and biochemistry, 2018-01, Vol.124 (1), p.61-68

2018

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Novel hydroxypyridinone derivatives containing an oxime ether moiety: Synthesis, inhibition on mushroom tyrosinase and application in anti-browning of fresh-cut apples

Food chemistry, 2018-03, Vol.242, p.174-181

2018

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Inhibition of human UDP-glucuronosyltransferase enzymes by lapatinib, pazopanib, regorafenib and sorafenib: Implications for hyperbilirubinemia

Biochemical pharmacology, 2017-04, Vol.129, p.85-95

2017

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Grape Seed and Tea Extracts and Catechin 3-Gallates Are Potent Inhibitors of α-Amylase and α-Glucosidase Activity

Journal of agricultural and food chemistry, 2012-09, Vol.60 (36), p.8924-8929

2012

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α-Glucosidase inhibition by luteolin: Kinetics, interaction and molecular docking

International journal of biological macromolecules, 2014-03, Vol.64, p.213-223

2014

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1 – 25 von 20.710

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Inhibition of angiotensin convertin enzyme (ACE) activity by the anthocyanins delphinidin- and cyanidin-3- O-sambubiosides from Hibiscus sabdariffa

Investigation on the metabolic characteristics of isobavachin in Psoralea corylifolia L. (Bu‐gu‐zhi) and its potential inhibition against human cytochrome P450s and UDP‐glucuronosyltransferases

Inhibitory Effects of Selected Antituberculosis Drugs on Common Human Hepatic Cytochrome P450 and UDP-glucuronosyltransferase Enzymes

What is the contribution of human FMO3 in the N-oxygenation of selected therapeutic drugs and drugs of abuse?

(99m)Tc-labeled gastrins of varying peptide chain length: Distinct impact of NEP/ACE-inhibition on stability and tumor uptake in mice

Comprehensive Evaluation for Substrate Selectivity of Cynomolgus Monkey Cytochrome P450 2C9, a New Efavirenz Oxidase

Residues Determining the Binding Specificity of Uncompetitive Inhibitors to Tissue‐Nonspecific Alkaline Phosphatase

Mechanism of Inhibition of Ebola Virus RNA-Dependent RNA Polymerase by Remdesivir

Identification of bla(IMP-22) in Pseudomonas spp. in urban wastewater and nosocomial environments: biochemical characterization of a new IMP metallo-enzyme variant and its genetic location

Challenges in the Discovery of Indoleamine 2,3-Dioxygenase 1 (IDO1) Inhibitors

Angiotensin-Converting Enzyme (ACE) Dimerization Is the Initial Step in the ACE Inhibitor-Induced ACE Signaling Cascade in Endothelial Cells

Structural Basis of Metallo-β-Lactamase Inhibition by Captopril Stereoisomers

Kojic acid–natural product conjugates as mushroom tyrosinase inhibitors

Expression, Purification, Characterization, and in Vivo Targeting of Trypanosome CTP Synthetase for Treatment of African Sleeping Sickness

IC50-to-Ki: a web-based tool for converting IC50 to Ki values for inhibitors of enzyme activity and ligand binding

Selective Sirt2 inhibition by ligand-induced rearrangement of the active site

Enzymes and nanoparticles: Modulation of enzymatic activity via nanoparticles

Synthesis and Multitarget Biological Profiling of a Novel Family of Rhein Derivatives As Disease-Modifying Anti-Alzheimer Agents

Identification of the human cytochrome P450 enzymes involved in the two oxidative steps in the bioactivation of clopidogrel to its pharmacologically active metabolite

Comparative Evaluation of Quercetin, Isoquercetin and Rutin as Inhibitors of α-Glucosidase

Synthesis of chalcone-imide derivatives and investigation of their anticancer and antimicrobial activities, carbonic anhydrase and acetylcholinesterase enzymes inhibition profiles

Novel hydroxypyridinone derivatives containing an oxime ether moiety: Synthesis, inhibition on mushroom tyrosinase and application in anti-browning of fresh-cut apples

Inhibition of human UDP-glucuronosyltransferase enzymes by lapatinib, pazopanib, regorafenib and sorafenib: Implications for hyperbilirubinemia

Grape Seed and Tea Extracts and Catechin 3-Gallates Are Potent Inhibitors of α-Amylase and α-Glucosidase Activity

α-Glucosidase inhibition by luteolin: Kinetics, interaction and molecular docking

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