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Chd7 is indispensable for mammalian brain development through activation of a neuronal differentiation programme

Nature communications, 2017-03, Vol.8 (1), p.14758-14758, Article 14758

2017

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TDP2 protects transcription from abortive topoisomerase activity and is required for normal neural function

Nature genetics, 2014-05, Vol.46 (5), p.516-521

2014

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CDK targets Sae2 to control DNA-end resection and homologous recombination

Nature, 2008-10, Vol.455 (7213), p.689-692

2008

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Double-strand breaks arising by replication through a nick are repaired by cohesin-dependent sister-chromatid exchange

EMBO reports, 2006-09, Vol.7 (9), p.919-926

2006

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TDP2/TTRAP Is the Major 5′-Tyrosyl DNA Phosphodiesterase Activity in Vertebrate Cells and Is Critical for Cellular Resistance to Topoisomerase II-induced DNA Damage

The Journal of biological chemistry, 2011-01, Vol.286 (1), p.403-409

2011

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Non-redundant Functions of ATM and DNA-PKcs in Response to DNA Double-Strand Breaks

Cell reports (Cambridge), 2015-11, Vol.13 (8), p.1598-1609

2015

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Does Tyrosyl DNA Phosphodiesterase-2 Play a Role in Hepatitis B Virus Genome Repair?

PloS one, 2015-06, Vol.10 (6), p.e0128401-e0128401

2015

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TDP2-dependent non-homologous end-joining protects against topoisomerase II-induced DNA breaks and genome instability in cells and in vivo

PLoS genetics, 2013-03, Vol.9 (3), p.e1003226

2013

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Topoisomerase IIα represses transcription by enforcing promoter-proximal pausing

Cell reports (Cambridge), 2021-04, Vol.35 (2), p.108977-108977, Article 108977

2021

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TDP2 suppresses genomic instability induced by androgens in the epithelial cells of prostate glands

Genes to cells : devoted to molecular & cellular mechanisms, 2020-07, Vol.25 (7), p.450-465

2020

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Data of transcriptional effects of the merbarone-mediated inhibition of TOP2

Data in brief, 2022-10, Vol.44, p.108499-108499, Article 108499

2022

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Genome-wide prediction of topoisomerase IIβ binding by architectural factors and chromatin accessibility

PLoS computational biology, 2021-01, Vol.17 (1), p.e1007814-e1007814

2021

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Endogenous topoisomerase II-mediated DNA breaks drive thymic cancer predisposition linked to ATM deficiency

Nature communications, 2020-02, Vol.11 (1), p.910-910, Article 910

2020

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Equal Sister Chromatid Exchange Is a Major Mechanism of Double-Strand Break Repair in Yeast

Molecular cell, 2003-06, Vol.11 (6), p.1661-1671

2003

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"An End to a Means": How DNA-End Structure Shapes the Double-Strand Break Repair Process

Frontiers in molecular biosciences, 2020-01, Vol.6, p.153-153

2020

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The Dot1 Histone Methyltransferase and the Rad9 Checkpoint Adaptor Contribute to Cohesin-Dependent Double-Strand Break Repair by Sister Chromatid Recombination in Saccharomyces cerevisiae

Genetics (Austin), 2009-06, Vol.182 (2), p.437-446

2009

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The absence of the yeast chromatin assembly factor Asf1 increases genomic instability and sister chromatid exchange

EMBO reports, 2004-05, Vol.5 (5), p.497-502

2004

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Divergent Requirement for a DNA Repair Enzyme during Enterovirus Infections

mBio, 2015-12, Vol.7 (1), p.e01931-e01915

2015

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A human 5'-tyrosyl DNA phosphodiesterase that repairs topoisomerase-mediated DNA damage

Nature (London), 2009-10, Vol.461 (7264), p.674-678

2009

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ATM specifically mediates repair of double-strand breaks with blocked DNA ends

Nature communications, 2014-02, Vol.5 (1), p.3347-3347, Article 3347

2014

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Ubiquitin stimulated reversal of topoisomerase 2 DNA-protein crosslinks by TDP2

Nucleic acids research, 2020-06, Vol.48 (11), p.6310

2020

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GSE4 peptide suppresses oxidative and telomere deficiencies in ataxia telangiectasia patient cells

Cell death and differentiation, 2019-10, Vol.26 (10), p.1998-2014

2019

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APLF (C2orf13) Is a Novel Component of Poly(ADP-Ribose) Signaling in Mammalian Cells

Molecular and Cellular Biology, 2008-07, Vol.28 (14), p.4620-4628

2008

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A Genetic Map of the Response to DNA Damage in Human Cells

Chd7 is indispensable for mammalian brain development through activation of a neuronal differentiation programme

TDP2 protects transcription from abortive topoisomerase activity and is required for normal neural function

CDK targets Sae2 to control DNA-end resection and homologous recombination

Double-strand breaks arising by replication through a nick are repaired by cohesin-dependent sister-chromatid exchange

TDP2/TTRAP Is the Major 5′-Tyrosyl DNA Phosphodiesterase Activity in Vertebrate Cells and Is Critical for Cellular Resistance to Topoisomerase II-induced DNA Damage

Non-redundant Functions of ATM and DNA-PKcs in Response to DNA Double-Strand Breaks

Does Tyrosyl DNA Phosphodiesterase-2 Play a Role in Hepatitis B Virus Genome Repair?

TDP2-dependent non-homologous end-joining protects against topoisomerase II-induced DNA breaks and genome instability in cells and in vivo

Topoisomerase IIα represses transcription by enforcing promoter-proximal pausing

TDP2 suppresses genomic instability induced by androgens in the epithelial cells of prostate glands

Data of transcriptional effects of the merbarone-mediated inhibition of TOP2

Genome-wide prediction of topoisomerase IIβ binding by architectural factors and chromatin accessibility

Endogenous topoisomerase II-mediated DNA breaks drive thymic cancer predisposition linked to ATM deficiency

Equal Sister Chromatid Exchange Is a Major Mechanism of Double-Strand Break Repair in Yeast

"An End to a Means": How DNA-End Structure Shapes the Double-Strand Break Repair Process

The Dot1 Histone Methyltransferase and the Rad9 Checkpoint Adaptor Contribute to Cohesin-Dependent Double-Strand Break Repair by Sister Chromatid Recombination in Saccharomyces cerevisiae

The absence of the yeast chromatin assembly factor Asf1 increases genomic instability and sister chromatid exchange

Divergent Requirement for a DNA Repair Enzyme during Enterovirus Infections

A human 5'-tyrosyl DNA phosphodiesterase that repairs topoisomerase-mediated DNA damage

ATM specifically mediates repair of double-strand breaks with blocked DNA ends

Ubiquitin stimulated reversal of topoisomerase 2 DNA-protein crosslinks by TDP2

GSE4 peptide suppresses oxidative and telomere deficiencies in ataxia telangiectasia patient cells

The insecticides permethrin and chlorpyrifos show limited genotoxicity and no leukemogenic potential in human and murine hematopoietic stem progenitor cells

APLF (C2orf13) Is a Novel Component of Poly(ADP-Ribose) Signaling in Mammalian Cells

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