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Single-chain fluorescent integrators for mapping G-protein-coupled receptor agonists

Proceedings of the National Academy of Sciences - PNAS, 2024-04, Vol.121 (18), p.e2307090121

2024

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Pharmacological properties of S1RA, a new sigma‐1 receptor antagonist that inhibits neuropathic pain and activity‐induced spinal sensitization

British journal of pharmacology, 2012-08, Vol.166 (8), p.2289-2306

2012

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Chemical Genomics Profiling of Environmental Chemical Modulation of Human Nuclear Receptors

Environmental health perspectives, 2011-08, Vol.119 (8), p.1142-1148

2011

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TAAR1 activation modulates monoaminergic neurotransmission, preventing hyperdopaminergic and hypoglutamatergic activity

Proceedings of the National Academy of Sciences - PNAS, 2011-05, Vol.108 (20), p.8485-8490

2011

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Nuclear Hormone Receptor Activity of Polybrominated Diphenyl Ethers and Their Hydroxylated and Methoxylated Metabolites in Transactivation Assays Using Chinese Hamster Ovary Cells

Environmental health perspectives, 2009-08, Vol.117 (8), p.1210-1218

2009

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Rearrangement of a polar core provides a conserved mechanism for constitutive activation of class B G protein-coupled receptors

The Journal of biological chemistry, 2017-06, Vol.292 (24), p.9865-9881

2017

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Topical Vitamin D3 and Low-Calcemic Analogs Induce Thymic Stromal Lymphopoietin in Mouse Keratinocytes and Trigger an Atopic Dermatitis

Proceedings of the National Academy of Sciences - PNAS, 2006-08, Vol.103 (31), p.11736-11741

2006

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Human Monocyte Subsets Are Transcriptionally and Functionally Altered in Aging in Response to Pattern Recognition Receptor Agonists

The Journal of immunology (1950), 2017-08, Vol.199 (4), p.1405-1417

2017

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Development of covalent inhibitors that can overcome resistance to first-generation FGFR kinase inhibitors

Proceedings of the National Academy of Sciences - PNAS, 2014-11, Vol.111 (45), p.E4869-E4877

2014

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Nanoscale co-organization and coactivation of AMPAR, NMDAR, and mGluR at excitatory synapses

Proceedings of the National Academy of Sciences - PNAS, 2020-06, Vol.117 (25), p.14503-14511

2020

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Mechanism of endosomal TLR inhibition by antimalarial drugs and imidazoquinolines

The Journal of immunology (1950), 2011-04, Vol.186 (8), p.4794-4804

2011

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Preclinical characterization of 1-7F9, a novel human anti–KIR receptor therapeutic antibody that augments natural killer–mediated killing of tumor cells

Blood, 2009-09, Vol.114 (13), p.2667-2677

2009

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CXCR4 inhibition in human pancreatic and colorectal cancers induces an integrated immune response

Proceedings of the National Academy of Sciences - PNAS, 2020-11, Vol.117 (46), p.28960-28970

2020

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Distinct functions of CXCR4, CCR2, and CX3CR1 direct dendritic cell precursors from the bone marrow to the lung

Journal of leukocyte biology, 2017-05, Vol.101 (5), p.1143-1153

2017

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Th17 plasticity in human autoimmune arthritis is driven by the inflammatory environment

Proceedings of the National Academy of Sciences - PNAS, 2010-08, Vol.107 (33), p.14751-14756

2010

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Multiple EphB Receptor Tyrosine Kinases Shape Dendritic Spines in the Hippocampus

The Journal of cell biology, 2003-12, Vol.163 (6), p.1313-1326

2003

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The highs and lows of cannabinoid receptor expression in disease: mechanisms and their therapeutic implications

Pharmacological reviews, 2011-09, Vol.63 (3), p.461

2011

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Amyloid-β Receptors: The Good, the Bad, and the Prion Protein

The Journal of biological chemistry, 2016-02, Vol.291 (7), p.3174-3183

2016

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Receptor activity‐modifying protein‐dependent effects of mutations in the calcitonin receptor‐like receptor: implications for adrenomedullin and calcitonin gene‐related peptide pharmacology

British journal of pharmacology, 2014-02, Vol.171 (3), p.772-788

2014

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Allosteric modulation of family C G-protein-coupled receptors: from molecular insights to therapeutic perspectives

Pharmacological reviews, 2011-03, Vol.63 (1), p.59

Urwyler, Stephan

2011

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Chemokine Receptor-Dependent Control of Skin Tissue-Resident Memory T Cell Formation

The Journal of immunology (1950), 2017-10, Vol.199 (7), p.2451-2459

2017

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Dopamine receptor D₃ regulates endocytic sorting by a Prazosin-sensitive interaction with the coatomer COPI

Proceedings of the National Academy of Sciences - PNAS, 2012-07, Vol.109 (31), p.12485-12490

2012

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The role of lipid-activated nuclear receptors in shaping macrophage and dendritic cell function: From physiology to pathology

Journal of allergy and clinical immunology, 2013-08, Vol.132 (2), p.264-286

2013

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Biglycan, a Danger Signal That Activates the NLRP3 Inflammasome via Toll-like and P2X Receptors

The Journal of biological chemistry, 2009-09, Vol.284 (36), p.24035-24048

2009

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Molecular basis for high-affinity agonist binding in GPCRs

Science (American Association for the Advancement of Science), 2019-05, Vol.364 (6442), p.775-778

2019

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Single-chain fluorescent integrators for mapping G-protein-coupled receptor agonists

Pharmacological properties of S1RA, a new sigma‐1 receptor antagonist that inhibits neuropathic pain and activity‐induced spinal sensitization

Chemical Genomics Profiling of Environmental Chemical Modulation of Human Nuclear Receptors

TAAR1 activation modulates monoaminergic neurotransmission, preventing hyperdopaminergic and hypoglutamatergic activity

Nuclear Hormone Receptor Activity of Polybrominated Diphenyl Ethers and Their Hydroxylated and Methoxylated Metabolites in Transactivation Assays Using Chinese Hamster Ovary Cells

Rearrangement of a polar core provides a conserved mechanism for constitutive activation of class B G protein-coupled receptors

Topical Vitamin D3 and Low-Calcemic Analogs Induce Thymic Stromal Lymphopoietin in Mouse Keratinocytes and Trigger an Atopic Dermatitis

Human Monocyte Subsets Are Transcriptionally and Functionally Altered in Aging in Response to Pattern Recognition Receptor Agonists

Development of covalent inhibitors that can overcome resistance to first-generation FGFR kinase inhibitors

Nanoscale co-organization and coactivation of AMPAR, NMDAR, and mGluR at excitatory synapses

Mechanism of endosomal TLR inhibition by antimalarial drugs and imidazoquinolines

Preclinical characterization of 1-7F9, a novel human anti–KIR receptor therapeutic antibody that augments natural killer–mediated killing of tumor cells

CXCR4 inhibition in human pancreatic and colorectal cancers induces an integrated immune response

Distinct functions of CXCR4, CCR2, and CX3CR1 direct dendritic cell precursors from the bone marrow to the lung

Th17 plasticity in human autoimmune arthritis is driven by the inflammatory environment

Multiple EphB Receptor Tyrosine Kinases Shape Dendritic Spines in the Hippocampus

The highs and lows of cannabinoid receptor expression in disease: mechanisms and their therapeutic implications

Amyloid-β Receptors: The Good, the Bad, and the Prion Protein

Receptor activity‐modifying protein‐dependent effects of mutations in the calcitonin receptor‐like receptor: implications for adrenomedullin and calcitonin gene‐related peptide pharmacology

Allosteric modulation of family C G-protein-coupled receptors: from molecular insights to therapeutic perspectives

Chemokine Receptor-Dependent Control of Skin Tissue-Resident Memory T Cell Formation

Dopamine receptor D₃ regulates endocytic sorting by a Prazosin-sensitive interaction with the coatomer COPI

The role of lipid-activated nuclear receptors in shaping macrophage and dendritic cell function: From physiology to pathology

Biglycan, a Danger Signal That Activates the NLRP3 Inflammasome via Toll-like and P2X Receptors

Molecular basis for high-affinity agonist binding in GPCRs

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