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N-acetyltransferase 2 genetic polymorphism modifies genotoxic and oxidative damage from new psychoactive substances

Archives of toxicology, 2023-01, Vol.97 (1), p.189-199

2023

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Acetylation of putative arylamine and alkylaniline carcinogens in immortalized human fibroblasts transfected with rapid and slow acetylator N-acetyltransferase 2 haplotypes

Archives of toxicology, 2021-01, Vol.95 (1), p.311-319

2021

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Effect of N-acetyltransferase 2 genetic polymorphism on 4,4′-methylenebis(2-chloroaniline)-induced genotoxicity and oxidative stress

Archives of toxicology, 2023-06, Vol.97 (6), p.1773-1781

2023

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Identification and characterization of potent, selective, and efficacious inhibitors of human arylamine N-acetyltransferase 1

Archives of toxicology, 2022-02, Vol.96 (2), p.511-524

2022

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Effects of dose and human N-acetyltransferase 1 genetic polymorphism in benzidine metabolism and genotoxicity

Archives of toxicology, 2023-06, Vol.97 (6), p.1765-1772

2023

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Differences in β-naphthylamine metabolism and toxicity in Chinese hamster ovary cell lines transfected with human CYP1A2 and NAT24, NAT25B or NAT27B N-acetyltransferase 2 haplotypes

Archives of toxicology, 2022-11, Vol.96 (11), p.2999-3012

2022

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Genetic heterogeneity among slow acetylator N-acetyltransferase 2 phenotypes in cryopreserved human hepatocytes

Archives of toxicology, 2017-07, Vol.91 (7), p.2655-2661

2017

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The effect of the rs1799931 G857A (G286E) polymorphism on N-acetyltransferase 2-mediated carcinogen metabolism and genotoxicity differs with heterocyclic amine exposure

Archives of toxicology, 2023-10, Vol.97 (10), p.2697-2705

2023

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Comparing N-acetylcysteine and 4-methylpyrazole as antidotes for acetaminophen overdose

Archives of toxicology, 2022-02, Vol.96 (2), p.453-465

2022

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Investigations on detoxification mechanisms of novel para-phenylenediamine analogues through N-acetyltransferase 1 (NAT-1)

Archives of toxicology, 2022, Vol.96 (1), p.153-165

2022

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First evidence of pyrrolizidine alkaloid N-oxide-induced hepatic sinusoidal obstruction syndrome in humans

Archives of toxicology, 2017-12, Vol.91 (12), p.3913-3925

2017

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Commentary of the SKLM to the EFSA opinion on risk assessment of N-nitrosamines in food

Archives of toxicology, 2024-06, Vol.98 (6), p.1573-1580

2024

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Physiologically-based pharmacokinetic model for evaluating gender-specific exposures of N-nitrosodimethylamine (NDMA)

Archives of toxicology, 2024-03, Vol.98 (3), p.821-835

2024

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The mixture of “ecstasy” and its metabolites is toxic to human SH-SY5Y differentiated cells at in vivo relevant concentrations

Archives of toxicology, 2014-02, Vol.88 (2), p.455-473

2014

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Recent progress in N-acetyltransferase research: 7th international workshop on N-acetyltransferases (NAT): workshop report

Archives of toxicology, 2017-07, Vol.91 (7), p.2715-2718

2017

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Toxic effects of A2E in human ARPE-19 cells were prevented by resveratrol: a potential nutritional bioactive for age-related macular degeneration treatment

Archives of toxicology, 2020-02, Vol.94 (2), p.553-572

2020

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Designer drugs: mechanism of action and adverse effects

Archives of toxicology, 2020-04, Vol.94 (4), p.1085-1133

2020

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Key factors of susceptibility to anti-tuberculosis drug-induced hepatotoxicity

Archives of toxicology, 2015-06, Vol.89 (6), p.883-897

2015

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"Ecstasy"-induced toxicity in SH-SY5Y differentiated cells: role of hyperthermia and metabolites

Archives of toxicology, 2014-02, Vol.88 (2), p.515-531

2014

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Determination of NAT2 acetylation status in the Greenlandic population

Archives of toxicology, 2016-04, Vol.90 (4), p.883-889

2016

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The role of endogenous versus exogenous sources in the exposome of putative genotoxins and consequences for risk assessment

Archives of toxicology, 2022-05, Vol.96 (5), p.1297-1352

2022

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Metabolism-mediated cytotoxicity and genotoxicity of pyrrolizidine alkaloids

Archives of toxicology, 2021-06, Vol.95 (6), p.1917-1942

2021

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Quantification of N-phenyl-2-naphthylamine by gas chromatography and isotope-dilution mass spectrometry and its percutaneous absorption ex vivo under workplace conditions

Archives of toxicology, 2017-11, Vol.91 (11), p.3587-3596

2017

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Formation of potentially toxic metabolites of drugs in reactions catalyzed by human drug-metabolizing enzymes

Archives of toxicology, 2024-06, Vol.98 (6), p.1581-1628

2024

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A human stem cell-derived test system for agents modifying neuronal N-methyl-D-aspartate-type glutamate receptor Ca 2+ -signalling

Archives of toxicology, 2021-05, Vol.95 (5), p.1703

2021

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N-acetyltransferase 2 genetic polymorphism modifies genotoxic and oxidative damage from new psychoactive substances

Acetylation of putative arylamine and alkylaniline carcinogens in immortalized human fibroblasts transfected with rapid and slow acetylator N-acetyltransferase 2 haplotypes

Effect of N-acetyltransferase 2 genetic polymorphism on 4,4′-methylenebis(2-chloroaniline)-induced genotoxicity and oxidative stress

Identification and characterization of potent, selective, and efficacious inhibitors of human arylamine N-acetyltransferase 1

Effects of dose and human N-acetyltransferase 1 genetic polymorphism in benzidine metabolism and genotoxicity

Differences in β-naphthylamine metabolism and toxicity in Chinese hamster ovary cell lines transfected with human CYP1A2 and NAT24, NAT25B or NAT27B N-acetyltransferase 2 haplotypes

Genetic heterogeneity among slow acetylator N-acetyltransferase 2 phenotypes in cryopreserved human hepatocytes

The effect of the rs1799931 G857A (G286E) polymorphism on N-acetyltransferase 2-mediated carcinogen metabolism and genotoxicity differs with heterocyclic amine exposure

Comparing N-acetylcysteine and 4-methylpyrazole as antidotes for acetaminophen overdose

Investigations on detoxification mechanisms of novel para-phenylenediamine analogues through N-acetyltransferase 1 (NAT-1)

First evidence of pyrrolizidine alkaloid N-oxide-induced hepatic sinusoidal obstruction syndrome in humans

Commentary of the SKLM to the EFSA opinion on risk assessment of N-nitrosamines in food

Physiologically-based pharmacokinetic model for evaluating gender-specific exposures of N-nitrosodimethylamine (NDMA)

The mixture of “ecstasy” and its metabolites is toxic to human SH-SY5Y differentiated cells at in vivo relevant concentrations

Recent progress in N-acetyltransferase research: 7th international workshop on N-acetyltransferases (NAT): workshop report

Toxic effects of A2E in human ARPE-19 cells were prevented by resveratrol: a potential nutritional bioactive for age-related macular degeneration treatment

Designer drugs: mechanism of action and adverse effects

Key factors of susceptibility to anti-tuberculosis drug-induced hepatotoxicity

"Ecstasy"-induced toxicity in SH-SY5Y differentiated cells: role of hyperthermia and metabolites

Determination of NAT2 acetylation status in the Greenlandic population

The role of endogenous versus exogenous sources in the exposome of putative genotoxins and consequences for risk assessment

Metabolism-mediated cytotoxicity and genotoxicity of pyrrolizidine alkaloids

Quantification of N-phenyl-2-naphthylamine by gas chromatography and isotope-dilution mass spectrometry and its percutaneous absorption ex vivo under workplace conditions

Formation of potentially toxic metabolites of drugs in reactions catalyzed by human drug-metabolizing enzymes

A human stem cell-derived test system for agents modifying neuronal N-methyl-D-aspartate-type glutamate receptor Ca 2+ -signalling

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