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Design, synthesis, and evaluation of amphiphilic sofalcone derivatives as potent Gram-positive antibacterial agents

European journal of medicinal chemistry, 2020-09, Vol.202, p.112596, Article 112596

2020

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Non-electrophilic modulators of the canonical Keap1/Nrf2 pathway

Bioorganic & medicinal chemistry letters, 2015-06, Vol.25 (11), p.2261-2268

2015

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Synthesis, docking study and inhibitory activity of 2,6-diketopiperazines derived from α-amino acids on HDAC8

Bioorganic chemistry, 2020-09, Vol.102, p.104080-104080, Article 104080

2020

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Design, synthesis and biological evaluation of 3-substituted indenoisoquinoline derivatives as topoisomerase I inhibitors

Bioorganic & medicinal chemistry letters, 2016-02, Vol.26 (3), p.1068-1072

2016

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Design, synthesis and biological evaluation of coumarin-based N-hydroxycinnamamide derivatives as novel histone deacetylase inhibitors with anticancer activities

Bioorganic chemistry, 2020-08, Vol.101, p.104023-104023, Article 104023

2020

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2-(4-Methylsulfonylaminophenyl) propanamide TRPV1 antagonists: Structure–activity relationships in the B and C-regions

Bioorganic & medicinal chemistry, 2012-02, Vol.20 (3), p.1310-1318

2012

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First synthesis of merged hybrids phosphorylated azirino[2,1-b]benzo[e][1,3]oxazine derivatives as anticancer agents

European journal of medicinal chemistry, 2020-01, Vol.185, p.111771-111771, Article 111771

2020

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Discovery of Dioxino[2,3-f]quinazoline derivative VEGFR-2 inhibitors exerting significant antipro-liferative activity in HUVECs and mice

European journal of medicinal chemistry, 2019-08, Vol.175, p.349-356

2019

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Biarylmethoxy 2-nitroimidazooxazine antituberculosis agents: Effects of proximal ring substitution and linker reversal on metabolism and efficacy

Bioorganic & medicinal chemistry letters, 2015-09, Vol.25 (18), p.3804-3809

2015

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Targeting epigenetic modulators using PROTAC degraders: Current status and future perspective

Bioorganic & medicinal chemistry letters, 2022-05, Vol.63, p.128653-128653, Article 128653

2022

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Synthesis, antiproliferative activity and molecular docking of thiocolchicine urethanes

Bioorganic chemistry, 2018-12, Vol.81, p.553-566

2018

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Fluoromethylcyclopropylamine derivatives as potential in vivo toxicophores – A cautionary disclosure

Bioorganic & medicinal chemistry letters, 2019-02, Vol.29 (4), p.560-562

2019

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Hepatoprotective activity of glucosyloxybenzyl succinate derivatives from the pseudobulbs of Pleione bulbocodioides

Phytochemistry (Oxford), 2019-01, Vol.157, p.71-81

2019

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Discovery of IDO1 inhibitors containing a decahydroquinoline, decahydro-1,6-naphthyridine, or octahydro-1H-pyrrolo[3,2-c]pyridine scaffold

Bioorganic & medicinal chemistry letters, 2021-10, Vol.49, p.128314-128314, Article 128314

2021

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Structure-activity relationships of trichothecenes against COLO201 cells and Cochliobolus miyabeanus: The role of 12-epoxide and macrocyclic moieties

Bioorganic & medicinal chemistry letters, 2019-04, Vol.29 (8), p.982-985

2019

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Synthesis, biological evaluation and molecular docking studies of new amides of 4-chlorothiocolchicine as anticancer agents

Bioorganic chemistry, 2020-04, Vol.97, p.103664-103664, Article 103664

2020

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Design and synthesis of multipotent 3-aminomethylindoles and 7-azaindoles with enhanced protein phosphatase 2A-activating profile and neuroprotection

European journal of medicinal chemistry, 2018-09, Vol.157, p.294-309

2018

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Peptide-decorated chitosan derivatives enhance fibroblast adhesion and proliferation in wound healing

Carbohydrate polymers, 2016-05, Vol.142, p.114-123

2016

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Naa10p Inhibits Beige Adipocyte-Mediated Thermogenesis through N-α-acetylation of Pgc1α

Molecular cell, 2019-11, Vol.76 (3), p.500-515.e8

2019

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Identification of novel antiplatelet agents by targeting Glycoprotein VI: A combined virtual screening study

Bioorganic chemistry, 2022-04, Vol.121, p.105661-105661, Article 105661

2022

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Potent inhibitors of SARS-CoV-2 3C-like protease derived from N-substituted isatin compounds

European journal of medicinal chemistry, 2020-11, Vol.206, p.112702-112702, Article 112702

2020

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Emerging roles of protein O-GlcNAcylation in cardiovascular diseases: Insights and novel therapeutic targets

Pharmacological research, 2021-03, Vol.165, p.105467-105467, Article 105467

2021

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Cytotoxic effects of intra and extracellular zinc chelation on human breast cancer cells

European journal of pharmacology, 2007-02, Vol.557 (1), p.9-19

2007

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The discovery of novel, potent ERR-alpha inverse agonists for the treatment of triple negative breast cancer

European journal of medicinal chemistry, 2017-08, Vol.136, p.457-467

2017

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Design, synthesis, and evaluation of amphiphilic sofalcone derivatives as potent Gram-positive antibacterial agents

Non-electrophilic modulators of the canonical Keap1/Nrf2 pathway

Synthesis, docking study and inhibitory activity of 2,6-diketopiperazines derived from α-amino acids on HDAC8

Design, synthesis and biological evaluation of 3-substituted indenoisoquinoline derivatives as topoisomerase I inhibitors

Design, synthesis and biological evaluation of coumarin-based N-hydroxycinnamamide derivatives as novel histone deacetylase inhibitors with anticancer activities

2-(4-Methylsulfonylaminophenyl) propanamide TRPV1 antagonists: Structure–activity relationships in the B and C-regions

First synthesis of merged hybrids phosphorylated azirino[2,1-b]benzo[e][1,3]oxazine derivatives as anticancer agents

Discovery of Dioxino[2,3-f]quinazoline derivative VEGFR-2 inhibitors exerting significant antipro-liferative activity in HUVECs and mice

Biarylmethoxy 2-nitroimidazooxazine antituberculosis agents: Effects of proximal ring substitution and linker reversal on metabolism and efficacy

Targeting epigenetic modulators using PROTAC degraders: Current status and future perspective

Synthesis, antiproliferative activity and molecular docking of thiocolchicine urethanes

Fluoromethylcyclopropylamine derivatives as potential in vivo toxicophores – A cautionary disclosure

Hepatoprotective activity of glucosyloxybenzyl succinate derivatives from the pseudobulbs of Pleione bulbocodioides

Discovery of IDO1 inhibitors containing a decahydroquinoline, decahydro-1,6-naphthyridine, or octahydro-1H-pyrrolo[3,2-c]pyridine scaffold

Structure-activity relationships of trichothecenes against COLO201 cells and Cochliobolus miyabeanus: The role of 12-epoxide and macrocyclic moieties

Synthesis, biological evaluation and molecular docking studies of new amides of 4-chlorothiocolchicine as anticancer agents

Treatment and prognostic factors for long-term outcome in patients with anti-NMDA receptor encephalitis: an observational cohort study

Design and synthesis of multipotent 3-aminomethylindoles and 7-azaindoles with enhanced protein phosphatase 2A-activating profile and neuroprotection

Peptide-decorated chitosan derivatives enhance fibroblast adhesion and proliferation in wound healing

Naa10p Inhibits Beige Adipocyte-Mediated Thermogenesis through N-α-acetylation of Pgc1α

Identification of novel antiplatelet agents by targeting Glycoprotein VI: A combined virtual screening study

Potent inhibitors of SARS-CoV-2 3C-like protease derived from N-substituted isatin compounds

Emerging roles of protein O-GlcNAcylation in cardiovascular diseases: Insights and novel therapeutic targets

Cytotoxic effects of intra and extracellular zinc chelation on human breast cancer cells

The discovery of novel, potent ERR-alpha inverse agonists for the treatment of triple negative breast cancer

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