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Inhibitors of the sulfur assimilation pathway in bacterial pathogens as enhancers of antibiotic therapy

Current medicinal chemistry, 2015-01, Vol.22 (2), p.187

2015

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Cycloserine enantiomers are reversible inhibitors of human alanine:glyoxylate aminotransferase: implications for Primary Hyperoxaluria type 1

Biochemical journal, 2019-12, Vol.476 (24), p.3751-3768

2019

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Refining the structure−activity relationships of 2-phenylcyclopropane carboxylic acids as inhibitors of O-acetylserine sulfhydrylase isoforms

Journal of enzyme inhibition and medicinal chemistry, 2019-01, Vol.34 (1), p.31-43

2019

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Discovery of novel fragments inhibiting O-acetylserine sulphhydrylase by combining scaffold hopping and ligand-based drug design

Journal of enzyme inhibition and medicinal chemistry, 2018-01, Vol.33 (1), p.1444-1452

2018

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Discovering a new class of antifungal agents that selectively inhibits microbial carbonic anhydrases

Journal of enzyme inhibition and medicinal chemistry, 2018-01, Vol.33 (1), p.1537-1544

2018

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Biochemical Characterization of Aspergillus fumigatus AroH, a Putative Aromatic Amino Acid Aminotransferase

Frontiers in molecular biosciences, 2018-11, Vol.5, p.104-104

2018

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Spectinamides: a challenge, a proof, and a suggestion

Trends in microbiology (Regular ed.), 2014-04, Vol.22 (4), p.170-171

2014

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Crystal structure of Aspergillus fumigatus AroH, an aromatic amino acid aminotransferase

Proteins, structure, function, and bioinformatics, 2022-02, Vol.90 (2), p.435-442

2022

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Cyclopropane derivatives as potential human serine racemase inhibitors: unveiling novel insights into a difficult target

Journal of enzyme inhibition and medicinal chemistry, 2016-07, Vol.31 (4), p.645-652

2016

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A combined ligand- and structure-based approach for the identification of rilmenidine-derived compounds which synergize the antitumor effects of doxorubicin

Bioorganic & medicinal chemistry, 2016-07, Vol.24 (14), p.3174-3183

2016

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Cyclopropane-1,2-dicarboxylic acids as new tools for the biophysical investigation of O-acetylserine sulfhydrylases by fluorimetric methods and saturation transfer difference (STD) NMR

Journal of enzyme inhibition and medicinal chemistry, 2016-11, Vol.31 (sup4), p.78-87

2016

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An Experimental Model for the Rapid Screening of Compounds with Potential Use Against Mycobacteria

Assay and drug development technologies, 2016-11, Vol.14 (9), p.524

2016

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6-Hydrogen-8-Methylquinolones Active Against Replicating and Non-replicating Mycobacterium tuberculosis

Chemical biology & drug design, 2012-11, Vol.80 (5), p.781-786

2012

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Searching for innovative quinolone-like scaffolds: synthesis and biological evaluation of 2,1-benzothiazine 2,2-dioxide derivatives

MedChemComm, 2012-09, Vol.3 (9), p.1092

2012

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HOPS/TMUB1 Enhances Apoptosis in TP53 Mutation-Independent Setting in Human Cancers

International journal of molecular sciences, 2024-05, Vol.25 (9), p.4600

2024

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The Circadian Protein PER1 Modulates the Cellular Response to Anticancer Treatments

International journal of molecular sciences, 2021-03, Vol.22 (6), p.2974

2021

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Smooth muscle cells in human atherosclerotic plaques secrete and proliferate in response to high mobility group box 1 protein

The FASEB journal, 2006-12, Vol.20 (14), p.2565-2566

2006

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Hops/Tmub1 Heterozygous Mouse Shows Haploinsufficiency Effect in Influencing p53-Mediated Apoptosis

International journal of molecular sciences, 2021-07, Vol.22 (13), p.7186

2021

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Mutations in the GLA Gene and LysoGb3: Is It Really Anderson-Fabry Disease?

International journal of molecular sciences, 2018-11, Vol.19 (12), p.3726

2018

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HOPS/TMUB1 retains p53 in the cytoplasm and sustains p53‐dependent mitochondrial apoptosis

EMBO reports, 2020-02, Vol.21 (2), p.e48073-n/a

2020

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Glucagon-like peptide 1 protects INS-1E mitochondria against palmitate-mediated beta-cell dysfunction: a proteomic study

Molecular bioSystems, 2015-06, Vol.11 (6), p.1696-1707

2015

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Effects of exogenous hexacosanoic acid on biochemical myelin composition in weaning and post-weaning rats

Neurochemical research, 1997-03, Vol.22 (3), p.327-331

1997

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Inhibitors of the sulfur assimilation pathway in bacterial pathogens as enhancers of antibiotic therapy

Cycloserine enantiomers are reversible inhibitors of human alanine:glyoxylate aminotransferase: implications for Primary Hyperoxaluria type 1

Refining the structure−activity relationships of 2-phenylcyclopropane carboxylic acids as inhibitors of O-acetylserine sulfhydrylase isoforms

Discovery of novel fragments inhibiting O-acetylserine sulphhydrylase by combining scaffold hopping and ligand-based drug design

Discovering a new class of antifungal agents that selectively inhibits microbial carbonic anhydrases

Biochemical Characterization of Aspergillus fumigatus AroH, a Putative Aromatic Amino Acid Aminotransferase

Spectinamides: a challenge, a proof, and a suggestion

Crystal structure of Aspergillus fumigatus AroH, an aromatic amino acid aminotransferase

Cyclopropane derivatives as potential human serine racemase inhibitors: unveiling novel insights into a difficult target

A combined ligand- and structure-based approach for the identification of rilmenidine-derived compounds which synergize the antitumor effects of doxorubicin

Cyclopropane-1,2-dicarboxylic acids as new tools for the biophysical investigation of O-acetylserine sulfhydrylases by fluorimetric methods and saturation transfer difference (STD) NMR

An Experimental Model for the Rapid Screening of Compounds with Potential Use Against Mycobacteria

6-Hydrogen-8-Methylquinolones Active Against Replicating and Non-replicating Mycobacterium tuberculosis

Searching for innovative quinolone-like scaffolds: synthesis and biological evaluation of 2,1-benzothiazine 2,2-dioxide derivatives

HOPS/TMUB1 Enhances Apoptosis in TP53 Mutation-Independent Setting in Human Cancers

The Circadian Protein PER1 Modulates the Cellular Response to Anticancer Treatments

Smooth muscle cells in human atherosclerotic plaques secrete and proliferate in response to high mobility group box 1 protein

Hops/Tmub1 Heterozygous Mouse Shows Haploinsufficiency Effect in Influencing p53-Mediated Apoptosis

Mutations in the GLA Gene and LysoGb3: Is It Really Anderson-Fabry Disease?

HOPS/TMUB1 retains p53 in the cytoplasm and sustains p53‐dependent mitochondrial apoptosis

Glucagon-like peptide 1 protects INS-1E mitochondria against palmitate-mediated beta-cell dysfunction: a proteomic study

Effects of exogenous hexacosanoic acid on biochemical myelin composition in weaning and post-weaning rats

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