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Structure-activity relationships of GPR120 agonists based on a docking simulation

Molecular pharmacology, 2010-11, Vol.78 (5), p.804-810

2010

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A natural small molecule pinocembrin resists high-fat diet-induced obesity through GPR120-ERK1/2 pathway

The Journal of nutritional biochemistry, 2024-09, Vol.135, p.109772, Article 109772

2024

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GPR120: a critical role in adipogenesis, inflammation, and energy metabolism in adipose tissue

Cellular and molecular life sciences : CMLS, 2017-08, Vol.74 (15), p.2723-2733

2017

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Positive Reinforcing Mechanisms between GPR120 and PPARγ Modulate Insulin Sensitivity

Cell metabolism, 2020-06, Vol.31 (6), p.1173-1188.e5

2020

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Loureirin B protects against obesity via activation of adipose tissue ω3 PUFA-GPR120-UCP1 axis in mice

Biochemical and biophysical research communications, 2022-12, Vol.632, p.139-149

2022

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Novel Fat Taste Receptor Agonists Curtail Progressive Weight Gain in Obese Male MiceSummary

Cellular and molecular gastroenterology and hepatology, 2023-01, Vol.15 (3), p.633-663

2023

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DHA supplementation prevent the progression of NASH via GPR120 signaling

European journal of pharmacology, 2018-02, Vol.820, p.31-38

2018

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Omega-3 Fatty Acids Activate Ciliary FFAR4 to Control Adipogenesis

Cell, 2019-11, Vol.179 (6), p.1289-1305.e21

2019

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Discovery of a Class of Endogenous Mammalian Lipids with Anti-Diabetic and Anti-inflammatory Effects

Cell, 2014-10, Vol.159 (2), p.318-332

2014

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Omega-3 from Flaxseed Oil Protects Obese Mice Against Diabetic Retinopathy Through GPR120 Receptor

Scientific reports, 2018-09, Vol.8 (1), p.14318-13, Article 14318

2018

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Gpr120 mRNA expression in gonadotropes in the mouse pituitary gland is regulated by free fatty acids

Journal of Reproduction and Development, 2020, pp.2019-166

2020

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The fungal 9‐methyl‐sphingadiene is a novel ligand for both PPARγ and GPR120

Journal of food biochemistry, 2018-10, Vol.42 (5), p.e12624-n/a

2018

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Vaccarin improves insulin sensitivity and glucose uptake in diet-induced obese mice via activation of GPR120-PI3K/AKT/GLUT4 pathway

Biochemical and biophysical research communications, 2022-12, Vol.634, p.189-195

2022

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Free-Fatty Acid Receptor-4 (FFA4/GPR120) differentially regulates migration, invasion, proliferation and tumor growth of papillary renal cell carcinoma cells

Biochemical pharmacology, 2023-07, Vol.213, p.115590-115590, Article 115590

2023

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Docosahexaenoic Acid Inhibits Inflammation-Induced Osteoclast Formation and Bone Resorption in vivo Through GPR120 by Inhibiting TNF-α Production in Macrophages and Directly Inhibiting Osteoclast Formation

Frontiers in endocrinology (Lausanne), 2019-03, Vol.10, p.157-157

2019

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Positive interplay between FFAR4/GPR120, DPP-IV inhibition and GLP-1 in beta cell proliferation and glucose homeostasis in obese high fat fed mice

Peptides (New York, N.Y. : 1980), 2024-07, Vol.177, p.171218, Article 171218

2024

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Nutritional Signaling via Free Fatty Acid Receptors

International Journal of Molecular Sciences, 2016-03, Vol.17 (4), p.450-450

2016

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Preference for dietary fat: From detection to disease

Progress in lipid research, 2020-04, Vol.78, p.101032-101032, Article 101032

2020

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Free fatty acid receptors as therapeutic targets for the treatment of diabetes

Frontiers in pharmacology, 2014-11, Vol.5, p.236-236

2014

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In silico and in vitro screening for potential anticancer candidates targeting GPR120

Bioorganic & medicinal chemistry letters, 2021-01, Vol.31, p.127672, Article 127672

2021

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Oral administration of linoleic acid immediately before glucose load ameliorates postprandial hyperglycemia

Frontiers in pharmacology, 2023-07, Vol.14, p.1197743-1197743

2023

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Omega-3 pleiad: The multipoint anti-inflammatory strategy

Critical reviews in food science and nutrition, 2024-05, Vol.64 (14), p.4817-4832

2024

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Flaxseed oil rich in omega-3 protects aorta against inflammation and endoplasmic reticulum stress partially mediated by GPR120 receptor in obese, diabetic and dyslipidemic mice models

The Journal of nutritional biochemistry, 2018-03, Vol.53, p.9-19

2018

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Unsaturated fatty acids from flaxseed oil and exercise modulate GPR120 but not GPR40 in the liver of obese mice: a new anti-inflammatory approach

The Journal of nutritional biochemistry, 2019-04, Vol.66, p.52-62

2019

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GPR120/FFAR4 stimulation attenuates airway remodeling and suppresses IL-4- and IL-13-induced airway epithelial injury via inhibition of STAT6 and Akt

Biomedicine & pharmacotherapy, 2023-12, Vol.168, p.115774-115774, Article 115774

2023

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Structure-activity relationships of GPR120 agonists based on a docking simulation

A natural small molecule pinocembrin resists high-fat diet-induced obesity through GPR120-ERK1/2 pathway

GPR120: a critical role in adipogenesis, inflammation, and energy metabolism in adipose tissue

Positive Reinforcing Mechanisms between GPR120 and PPARγ Modulate Insulin Sensitivity

Loureirin B protects against obesity via activation of adipose tissue ω3 PUFA-GPR120-UCP1 axis in mice

Novel Fat Taste Receptor Agonists Curtail Progressive Weight Gain in Obese Male MiceSummary

DHA supplementation prevent the progression of NASH via GPR120 signaling

Omega-3 Fatty Acids Activate Ciliary FFAR4 to Control Adipogenesis

Discovery of a Class of Endogenous Mammalian Lipids with Anti-Diabetic and Anti-inflammatory Effects

Omega-3 from Flaxseed Oil Protects Obese Mice Against Diabetic Retinopathy Through GPR120 Receptor

Gpr120 mRNA expression in gonadotropes in the mouse pituitary gland is regulated by free fatty acids

The fungal 9‐methyl‐sphingadiene is a novel ligand for both PPARγ and GPR120

Vaccarin improves insulin sensitivity and glucose uptake in diet-induced obese mice via activation of GPR120-PI3K/AKT/GLUT4 pathway

Free-Fatty Acid Receptor-4 (FFA4/GPR120) differentially regulates migration, invasion, proliferation and tumor growth of papillary renal cell carcinoma cells

Docosahexaenoic Acid Inhibits Inflammation-Induced Osteoclast Formation and Bone Resorption in vivo Through GPR120 by Inhibiting TNF-α Production in Macrophages and Directly Inhibiting Osteoclast Formation

Positive interplay between FFAR4/GPR120, DPP-IV inhibition and GLP-1 in beta cell proliferation and glucose homeostasis in obese high fat fed mice

Nutritional Signaling via Free Fatty Acid Receptors

Preference for dietary fat: From detection to disease

Free fatty acid receptors as therapeutic targets for the treatment of diabetes

In silico and in vitro screening for potential anticancer candidates targeting GPR120

Oral administration of linoleic acid immediately before glucose load ameliorates postprandial hyperglycemia

Omega-3 pleiad: The multipoint anti-inflammatory strategy

Flaxseed oil rich in omega-3 protects aorta against inflammation and endoplasmic reticulum stress partially mediated by GPR120 receptor in obese, diabetic and dyslipidemic mice models

Unsaturated fatty acids from flaxseed oil and exercise modulate GPR120 but not GPR40 in the liver of obese mice: a new anti-inflammatory approach

GPR120/FFAR4 stimulation attenuates airway remodeling and suppresses IL-4- and IL-13-induced airway epithelial injury via inhibition of STAT6 and Akt

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