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Overexpression of human wild-type FUS causes progressive motor neuron degeneration in an age- and dose-dependent fashion

Acta neuropathologica, 2013-02, Vol.125 (2), p.273-288

2013

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Role of Axonal Transport in Neurodegenerative Diseases

Annual review of neuroscience, 2008-01, Vol.31 (1), p.151-173

2008

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The VAPB-PTPIP51 endoplasmic reticulum-mitochondria tethering proteins are present in neuronal synapses and regulate synaptic activity

Acta neuropathologica communications, 2019-03, Vol.7 (1), p.35-13, Article 35

2019

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The importance of tau phosphorylation for neurodegenerative diseases

Frontiers in neurology, 2013-01, Vol.4, p.83-83

2013

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Direct evidence for axonal transport defects in a novel mouse model of mutant spastin-induced hereditary spastic paraplegia (HSP) and human HSP patients

Journal of neurochemistry, 2009-07, Vol.110 (1), p.34-44

2009

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ER–mitochondria associations are regulated by the VAPB–PTPIP51 interaction and are disrupted by ALS/FTD-associated TDP-43

Nature communications, 2014-06, Vol.5 (1), p.3996-3996, Article 3996

2014

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There's Something Wrong with my MAM; the ER–Mitochondria Axis and Neurodegenerative Diseases

Trends in neurosciences (Regular ed.), 2016-03, Vol.39 (3), p.146-157

2016

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The lemur tail kinase family in neuronal function and disfunction in neurodegenerative diseases

Cellular and molecular life sciences : CMLS, 2024-12, Vol.81 (1), p.447, Article 447

2024

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Cdk5/p35 phosphorylates lemur tyrosine kinase-2 to regulate protein phosphatase-1C phosphorylation and activity

Journal of neurochemistry, 2012-05, Vol.121 (3), p.343-348

2012

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Increasing microtubule acetylation rescues axonal transport and locomotor deficits caused by LRRK2 Roc-COR domain mutations

Nature communications, 2014-10, Vol.5 (1), p.5245-5245, Article 5245

2014

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Kinesin light chain-1 serine-460 phosphorylation is altered in Alzheimer's disease and regulates axonal transport and processing of the amyloid precursor protein

Acta neuropathologica communications, 2019-12, Vol.7 (1), p.200-200, Article 200

2019

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A revised nomenclature for the lemur family of protein kinases

Communications biology, 2024-01, Vol.7 (1), p.57-5, Article 57

2024

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Dissociation of Axonal Neurofilament Content from Its Transport Rate

PloS one, 2015-07, Vol.10 (7), p.e0133848-e0133848

2015

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LMTK2 binds to kinesin light chains to mediate anterograde axonal transport of cdk5/p35 and LMTK2 levels are reduced in Alzheimer's disease brains

Acta neuropathologica communications, 2019-05, Vol.7 (1), p.73-73, Article 73

2019

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The ER-Mitochondria Tethering Complex VAPB-PTPIP51 Regulates Autophagy

Current biology, 2017-02, Vol.27 (3), p.371-385

2017

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Phosphorylation of kinesin light chain 1 at serine 460 modulates binding and trafficking of calsyntenin-1

Journal of cell science, 2011-04, Vol.124 (Pt 7), p.1032-1042

2011

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ER-mitochondria signaling regulates autophagy

Autophagy, 2017-07, Vol.13 (7), p.1250-1251

2017

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Riluzole protects against glutamate-induced slowing of neurofilament axonal transport

Neuroscience letters, 2009-04, Vol.454 (2), p.161-164

2009

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α-Synuclein binds to the ER–mitochondria tethering protein VAPB to disrupt Ca2+ homeostasis and mitochondrial ATP production

Acta neuropathologica, 2017-07, Vol.134 (1), p.129-149

2017

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Targeting ER-Mitochondria Signaling as a Therapeutic Target for Frontotemporal Dementia and Related Amyotrophic Lateral Sclerosis

Frontiers in cell and developmental biology, 2022-05, Vol.10, p.915931-915931

2022

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The Four Major N- and C-Terminal Splice Variants of the Excitatory Amino Acid Transporter GLT-1 Form Cell Surface Homomeric and Heteromeric Assemblies

Molecular pharmacology, 2009-05, Vol.75 (5), p.1062-1073

2009

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Identification of a Novel, Membrane-Associated Neuronal Kinase, Cyclin-Dependent Kinase 5/p35-Regulated Kinase

The Journal of neuroscience, 2003-06, Vol.23 (12), p.4975-4983

2003

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Poor communication between ER and mitochondria: a signature of ALS/FTD?

Aging (Albany, NY.), 2023-10, Vol.15 (20), p.10814-10816

2023

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Neurofilaments and neurological disease

BioEssays, 2003-04, Vol.25 (4), p.346-355

2003

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ALS/FTD-associated FUS activates GSK-3β to disrupt the VAPB-PTPIP51 interaction and ER-mitochondria associations

EMBO reports, 2016-09, Vol.17 (9), p.1326-1342

2016

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Overexpression of human wild-type FUS causes progressive motor neuron degeneration in an age- and dose-dependent fashion

Role of Axonal Transport in Neurodegenerative Diseases

The VAPB-PTPIP51 endoplasmic reticulum-mitochondria tethering proteins are present in neuronal synapses and regulate synaptic activity

The importance of tau phosphorylation for neurodegenerative diseases

Direct evidence for axonal transport defects in a novel mouse model of mutant spastin-induced hereditary spastic paraplegia (HSP) and human HSP patients

ER–mitochondria associations are regulated by the VAPB–PTPIP51 interaction and are disrupted by ALS/FTD-associated TDP-43

There's Something Wrong with my MAM; the ER–Mitochondria Axis and Neurodegenerative Diseases

The lemur tail kinase family in neuronal function and disfunction in neurodegenerative diseases

Cdk5/p35 phosphorylates lemur tyrosine kinase-2 to regulate protein phosphatase-1C phosphorylation and activity

Increasing microtubule acetylation rescues axonal transport and locomotor deficits caused by LRRK2 Roc-COR domain mutations

Kinesin light chain-1 serine-460 phosphorylation is altered in Alzheimer's disease and regulates axonal transport and processing of the amyloid precursor protein

A revised nomenclature for the lemur family of protein kinases

Dissociation of Axonal Neurofilament Content from Its Transport Rate

LMTK2 binds to kinesin light chains to mediate anterograde axonal transport of cdk5/p35 and LMTK2 levels are reduced in Alzheimer's disease brains

The ER-Mitochondria Tethering Complex VAPB-PTPIP51 Regulates Autophagy

Phosphorylation of kinesin light chain 1 at serine 460 modulates binding and trafficking of calsyntenin-1

ER-mitochondria signaling regulates autophagy

Riluzole protects against glutamate-induced slowing of neurofilament axonal transport

α-Synuclein binds to the ER–mitochondria tethering protein VAPB to disrupt Ca2+ homeostasis and mitochondrial ATP production

Targeting ER-Mitochondria Signaling as a Therapeutic Target for Frontotemporal Dementia and Related Amyotrophic Lateral Sclerosis

The Four Major N- and C-Terminal Splice Variants of the Excitatory Amino Acid Transporter GLT-1 Form Cell Surface Homomeric and Heteromeric Assemblies

Identification of a Novel, Membrane-Associated Neuronal Kinase, Cyclin-Dependent Kinase 5/p35-Regulated Kinase

Poor communication between ER and mitochondria: a signature of ALS/FTD?

Neurofilaments and neurological disease

ALS/FTD-associated FUS activates GSK-3β to disrupt the VAPB-PTPIP51 interaction and ER-mitochondria associations

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