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Defective mitophagy in Alzheimer’s disease

Ageing research reviews, 2020-12, Vol.64, p.101191-101191, Article 101191

2020

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Synaptic basis of Alzheimer’s disease: Focus on synaptic amyloid beta, P-tau and mitochondria

Ageing research reviews, 2021-01, Vol.65, p.101208-101208, Article 101208

2021

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Mitochondrial division inhibitor 1 reduces dynamin-related protein 1 and mitochondrial fission activity

Human molecular genetics, 2019-01, Vol.28 (2), p.177-199

2019

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Common neurodegenerative pathways in obesity, diabetes, and Alzheimer's disease

Biochimica et biophysica acta. Molecular basis of disease, 2017-05, Vol.1863 (5), p.1037-1045

2017

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Are circulating microRNAs peripheral biomarkers for Alzheimer's disease?

Biochimica et biophysica acta, 2016-09, Vol.1862 (9), p.1617-1627

2016

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Mitochondrial dysfunction and oxidative stress in metabolic disorders — A step towards mitochondria based therapeutic strategies

Biochimica et biophysica acta. Molecular basis of disease, 2017-05, Vol.1863 (5), p.1066-1077

2017

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Phosphorylated tau targeted small-molecule PROTACs for the treatment of Alzheimer's disease and tauopathies

Biochimica et biophysica acta. Molecular basis of disease, 2021-08, Vol.1867 (8), p.166162-166162, Article 166162

2021

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Mitochondrial division inhibitor 1 protects against mutant huntingtin-induced abnormal mitochondrial dynamics and neuronal damage in Huntington's disease

Human molecular genetics, 2015-12, Vol.24 (25), p.7308-7325

2015

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Abnormal mitochondrial dynamics, mitochondrial loss and mutant huntingtin oligomers in Huntington's disease: implications for selective neuronal damage

Human molecular genetics, 2011-04, Vol.20 (7), p.1438-1455

2011

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Abnormal interaction of VDAC1 with amyloid beta and phosphorylated tau causes mitochondrial dysfunction in Alzheimer's disease

Human molecular genetics, 2012-12, Vol.21 (23), p.5131-5146

2012

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Defective Autophagy and Mitophagy in Aging and Alzheimer's Disease

Frontiers in neuroscience, 2021-01, Vol.14, p.612757-612757

2021

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Hippocampal mutant APP and amyloid beta-induced cognitive decline, dendritic spine loss, defective autophagy, mitophagy and mitochondrial abnormalities in a mouse model of Alzheimer's disease

Human molecular genetics, 2018-04, Vol.27 (8), p.1332-1342

2018

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Increased mitochondrial fission and neuronal dysfunction in Huntington's disease: implications for molecular inhibitors of excessive mitochondrial fission

Drug discovery today, 2014-07, Vol.19 (7), p.951-955

Reddy, P. Hemachandra

2014

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Dynamics of diabetes and obesity: Epidemiological perspective

Biochimica et biophysica acta. Molecular basis of disease, 2017-05, Vol.1863 (5), p.1026-1036

2017

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Impaired mitochondrial dynamics and abnormal interaction of amyloid beta with mitochondrial protein Drp1 in neurons from patients with Alzheimer's disease: implications for neuronal damage

Human molecular genetics, 2011-07, Vol.20 (13), p.2495-2509

2011

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MicroRNA-455-3p as a potential peripheral biomarker for Alzheimer's disease

Human molecular genetics, 2017-10, Vol.26 (19), p.3808-3822

2017

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Protective effects of reduced dynamin-related protein 1 against amyloid beta-induced mitochondrial dysfunction and synaptic damage in Alzheimer's disease

Human molecular genetics, 2016-12, Vol.25 (23), p.5148-5166

2016

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Hippocampal phosphorylated tau induced cognitive decline, dendritic spine loss and mitochondrial abnormalities in a mouse model of Alzheimer's disease

Human molecular genetics, 2018-01, Vol.27 (1), p.30-40

2018

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Impact of COVID-19 on Mitochondrial-Based Immunity in Aging and Age-Related Diseases

Frontiers in aging neuroscience, 2021-01, Vol.12, p.614650-614650

2021

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Abnormal tau, mitochondrial dysfunction, impaired axonal transport of mitochondria, and synaptic deprivation in Alzheimer's disease

Brain research, 2011-09, Vol.1415, p.136-148

Reddy, P. Hemachandra

2011

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Peripheral biomarkers of stroke: Focus on circulatory microRNAs

Biochimica et biophysica acta, 2016-10, Vol.1862 (10), p.1984-1993

2016

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Amyloid precursor protein‐mediated free radicals and oxidative damage: Implications for the development and progression of Alzheimer's disease

Journal of neurochemistry, 2006-01, Vol.96 (1), p.1-13

Reddy, P. Hemachandra

2006

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Mitochondria-targeted small molecule SS31: a potential candidate for the treatment of Alzheimer's disease

Human molecular genetics, 2017-04, Vol.26 (8), p.1483-1496

2017

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Abnormal interaction between the mitochondrial fission protein Drp1 and hyperphosphorylated tau in Alzheimer's disease neurons: implications for mitochondrial dysfunction and neuronal damage

Human molecular genetics, 2012-06, Vol.21 (11), p.2538-2547

2012

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Aging and amyloid beta-induced oxidative DNA damage and mitochondrial dysfunction in Alzheimer's disease: Implications for early intervention and therapeutics

Biochimica et biophysica acta, 2011-11, Vol.1812 (11), p.1359-1370

2011

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Defective mitophagy in Alzheimer’s disease

Synaptic basis of Alzheimer’s disease: Focus on synaptic amyloid beta, P-tau and mitochondria

Mitochondrial division inhibitor 1 reduces dynamin-related protein 1 and mitochondrial fission activity

Common neurodegenerative pathways in obesity, diabetes, and Alzheimer's disease

Are circulating microRNAs peripheral biomarkers for Alzheimer's disease?

Mitochondrial dysfunction and oxidative stress in metabolic disorders — A step towards mitochondria based therapeutic strategies

Phosphorylated tau targeted small-molecule PROTACs for the treatment of Alzheimer's disease and tauopathies

Mitochondrial division inhibitor 1 protects against mutant huntingtin-induced abnormal mitochondrial dynamics and neuronal damage in Huntington's disease

Abnormal mitochondrial dynamics, mitochondrial loss and mutant huntingtin oligomers in Huntington's disease: implications for selective neuronal damage

Abnormal interaction of VDAC1 with amyloid beta and phosphorylated tau causes mitochondrial dysfunction in Alzheimer's disease

Defective Autophagy and Mitophagy in Aging and Alzheimer's Disease

Hippocampal mutant APP and amyloid beta-induced cognitive decline, dendritic spine loss, defective autophagy, mitophagy and mitochondrial abnormalities in a mouse model of Alzheimer's disease

Increased mitochondrial fission and neuronal dysfunction in Huntington's disease: implications for molecular inhibitors of excessive mitochondrial fission

Dynamics of diabetes and obesity: Epidemiological perspective

Impaired mitochondrial dynamics and abnormal interaction of amyloid beta with mitochondrial protein Drp1 in neurons from patients with Alzheimer's disease: implications for neuronal damage

MicroRNA-455-3p as a potential peripheral biomarker for Alzheimer's disease

Protective effects of reduced dynamin-related protein 1 against amyloid beta-induced mitochondrial dysfunction and synaptic damage in Alzheimer's disease

Hippocampal phosphorylated tau induced cognitive decline, dendritic spine loss and mitochondrial abnormalities in a mouse model of Alzheimer's disease

Impact of COVID-19 on Mitochondrial-Based Immunity in Aging and Age-Related Diseases

Abnormal tau, mitochondrial dysfunction, impaired axonal transport of mitochondria, and synaptic deprivation in Alzheimer's disease

Peripheral biomarkers of stroke: Focus on circulatory microRNAs

Amyloid precursor protein‐mediated free radicals and oxidative damage: Implications for the development and progression of Alzheimer's disease

Mitochondria-targeted small molecule SS31: a potential candidate for the treatment of Alzheimer's disease

Abnormal interaction between the mitochondrial fission protein Drp1 and hyperphosphorylated tau in Alzheimer's disease neurons: implications for mitochondrial dysfunction and neuronal damage

Aging and amyloid beta-induced oxidative DNA damage and mitochondrial dysfunction in Alzheimer's disease: Implications for early intervention and therapeutics

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