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Changes in Nutritional Status Impact Immune Cell Metabolism and Function

Frontiers in immunology, 2018-05, Vol.9, p.1055-1055

2018

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Effects of T cell leptin signaling on systemic glucose tolerance and T cell responses in obesity

PloS one, 2023-06, Vol.18 (6), p.e0286470-e0286470

2023

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Insulin and IGF-1 have both overlapping and distinct effects on CD4+ T cell mitochondria, metabolism, and function

Scientific reports, 2024-02, Vol.14 (1), p.4331-4331, Article 4331

2024

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Targeting T-cell oxidative metabolism to improve influenza survival in a mouse model of obesity

International Journal of Obesity, 2020-12, Vol.44 (12), p.2419-2429

2020

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Fasnall, a Selective FASN Inhibitor, Shows Potent Anti-tumor Activity in the MMTV-Neu Model of HER2+ Breast Cancer

Cell chemical biology, 2016-06, Vol.23 (6), p.678-688

2016

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Irgm1 regulates metabolism and function in T cell subsets

Scientific reports, 2022-01, Vol.12 (1), p.850-850, Article 850

2022

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Cellular fatty acid synthase is required for late stages of HIV-1 replication

Retrovirology, 2017-09, Vol.14 (1), p.45-45, Article 45

2017

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Metformin treatment of CD8 T cells decreases pro-inflammatory cytokine production and shifts their metabolic state toward oxidative metabolism

The Journal of immunology (1950), 2023-05, Vol.210 (1_Supplement), p.66-66.12

2023

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Emerging mechanisms of obesity-associated immune dysfunction

Nature reviews. Endocrinology, 2024-03, Vol.20 (3), p.136-148

2024

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Alveolar and Bone Marrow-derived Macrophages Differ in Metabolism and Glutamine Utilization

American journal of respiratory cell and molecular biology, 2024-11

2024

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Type I interferon signaling and peroxisomal dysfunction contribute to enhanced inflammatory cytokine production in IRGM1-deficient macrophages

The Journal of biological chemistry, 2024-11, Vol.300 (11), p.107883, Article 107883

2024

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Abstract 4457: Novel fatty-acid synthase inhibitor in combination with platinum-based therapy provides increased tumor killing efficacy in luminal breast murine model

Cancer research (Chicago, Ill.), 2015-08, Vol.75 (15_Supplement), p.4457-4457

2015

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Abstract 2703: Overcoming Lapatinib resistance by the fatty acid synthase inhibitor HS-106

Cancer research (Chicago, Ill.), 2015-08, Vol.75 (15_Supplement), p.2703-2703

2015

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Abstract 2219: Cancer prevention using a novel fatty acid synthase inhibitor

Cancer research (Chicago, Ill.), 2017-07, Vol.77 (13_Supplement), p.2219-2219

2017

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OR12-2 Obesity Induces Changes in T Cell Metabolism and Function

Journal of the Endocrine Society, 2019-04, Vol.3 (Supplement_1)

2019

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Discovery and Characterization of a Novel Fatty Acid Synthase Inhibitor with Antineoplastic Activity Against Breast Cancer

Alwarawrah, Yazan

2016

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Identification of an Allosteric Small-Molecule Inhibitor Selective for the Inducible Form of Heat Shock Protein 70

Chemistry & biology, 2014-12, Vol.21 (12), p.1648-1659

2014

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Immune Function in Obesity

Pediatric Obesity, 2018, p.363-378

2018

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Changes in Nutritional Status Impact Immune Cell Metabolism and Function

Effects of T cell leptin signaling on systemic glucose tolerance and T cell responses in obesity

Insulin and IGF-1 have both overlapping and distinct effects on CD4+ T cell mitochondria, metabolism, and function

Targeting T-cell oxidative metabolism to improve influenza survival in a mouse model of obesity

Fasnall, a Selective FASN Inhibitor, Shows Potent Anti-tumor Activity in the MMTV-Neu Model of HER2+ Breast Cancer

Irgm1 regulates metabolism and function in T cell subsets

Cellular fatty acid synthase is required for late stages of HIV-1 replication

Metformin treatment of CD8 T cells decreases pro-inflammatory cytokine production and shifts their metabolic state toward oxidative metabolism

Emerging mechanisms of obesity-associated immune dysfunction

Alveolar and Bone Marrow-derived Macrophages Differ in Metabolism and Glutamine Utilization

Type I interferon signaling and peroxisomal dysfunction contribute to enhanced inflammatory cytokine production in IRGM1-deficient macrophages

Abstract 4457: Novel fatty-acid synthase inhibitor in combination with platinum-based therapy provides increased tumor killing efficacy in luminal breast murine model

Abstract 2703: Overcoming Lapatinib resistance by the fatty acid synthase inhibitor HS-106

Abstract 2219: Cancer prevention using a novel fatty acid synthase inhibitor

OR12-2 Obesity Induces Changes in T Cell Metabolism and Function

Discovery and Characterization of a Novel Fatty Acid Synthase Inhibitor with Antineoplastic Activity Against Breast Cancer

Identification of an Allosteric Small-Molecule Inhibitor Selective for the Inducible Form of Heat Shock Protein 70

Immune Function in Obesity

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