UB Paderborn / Katalog / Suche / in CDI

1 – 25 von 39

Sortiert nach

Physiologically Based Oral Absorption Modelling to Study Gut-Level Drug Interactions

Journal of pharmaceutical sciences, 2018-01, Vol.107 (1), p.18-23

2018

Volltextzugriff (PDF)

Application of Absorption Modeling in Rational Design of Drug Product Under Quality-by-Design Paradigm

The AAPS journal, 2015-09, Vol.17 (5), p.1224-1236

2015

Volltextzugriff (PDF)

Understanding the Effect of API Properties on Bioavailability Through Absorption Modeling

The AAPS journal, 2008-12, Vol.10 (4), p.516-525

2008

Volltextzugriff (PDF)

Crystalline Nanosuspensions as Potential Toxicology and Clinical Oral Formulations for BCS II/IV Compounds

The AAPS journal, 2012-12, Vol.14 (4), p.677-687

2012

Volltextzugriff (PDF)

Establishing the Bioequivalence Safe Space for Immediate-Release Oral Dosage Forms using Physiologically Based Biopharmaceutics Modeling (PBBM): Case Studies

Journal of pharmaceutical sciences, 2021-12, Vol.110 (12), p.3896-3906

2021

Volltextzugriff (PDF)

Assessment of food effects during clinical development

International journal of pharmaceutics, 2023-03, Vol.635, p.122758-122758, Article 122758

2023

Volltextzugriff (PDF)

Amorphous Solid Dispersions or Prodrugs: Complementary Strategies to Increase Drug Absorption

Journal of pharmaceutical sciences, 2016-09, Vol.105 (9), p.2498-2508

2016

Volltextzugriff (PDF)

The impact of reduced gastric acid secretion on dissolution of salts of weak bases in the fasted upper gastrointestinal lumen: Data in biorelevant media and in human aspirates

European journal of pharmaceutics and biopharmaceutics, 2017-06, Vol.115, p.94-101

2017

Volltextzugriff (PDF)

Physiologically Based Absorption Modeling for Amorphous Solid Dispersion Formulations

Molecular pharmaceutics, 2016-09, Vol.13 (9), p.3206-3215

2016

Volltextzugriff (PDF)

Food Effect Projections via Physiologically Based Pharmacokinetic Modeling: Predictive Case Studies

Journal of pharmaceutical sciences, 2019-01, Vol.108 (1), p.592-602

2019

Volltextzugriff (PDF)

Utility of PBPK Absorption Modeling to Guide Modified Release Formulation Development of Gaboxadol, a Highly Soluble Compound With Region-Dependent Absorption

Journal of pharmaceutical sciences, 2016-02, Vol.105 (2), p.722-728

2016

Volltextzugriff (PDF)

Development of In Vitro–In Vivo Correlation for Amorphous Solid Dispersion Immediate-Release Suvorexant Tablets and Application to Clinically Relevant Dissolution Specifications and In-Process Controls

Journal of pharmaceutical sciences, 2015-09, Vol.104 (9), p.2913-2922

2015

Volltextzugriff (PDF)

Industry's View on Using Quality Control, Biorelevant, and Clinically Relevant Dissolution Tests for Pharmaceutical Development, Registration, and Commercialization

Journal of pharmaceutical sciences, 2018-01, Vol.107 (1), p.34-41

2018

Volltextzugriff (PDF)

Physiologically based Pharmacokinetic Models under the Prism of the Finite Absorption Time Concept

Pharmaceutical research, 2023-02, Vol.40 (2), p.419-429

2023

Volltextzugriff (PDF)

An Extrusion Spheronization Approach to Enable a High Drug Load Formulation of a Poorly Soluble Drug with a Low Melting Surfactant

Journal of pharmaceutical sciences, 2015-11, Vol.104 (11), p.3752-3759

2015

Volltextzugriff (PDF)

Forecasting in vivo oral absorption and food effect of micronized and nanosized aprepitant formulations in humans

European journal of pharmaceutics and biopharmaceutics, 2010-09, Vol.76 (1), p.95-104

2010

Volltextzugriff (PDF)

Evaluation of Dissolution in the Lower Intestine and Its Impact on the Absorption Process of High Dose Low Solubility Drugs

Molecular pharmaceutics, 2017-12, Vol.14 (12), p.4181-4191

2017

Volltextzugriff (PDF)

Dissolution and Translational Modeling Strategies Enabling Patient-Centric Drug Product Development: the M-CERSI Workshop Summary Report

The AAPS journal, 2018-05, Vol.20 (3), p.60-60, Article 60

2018

Volltextzugriff (PDF)

Use of Physiologically Based Pharmacokinetic Modeling for Predicting Drug–Food Interactions: Recommendations for Improving Predictive Performance of Low Confidence Food Effect Models

The AAPS journal, 2021-06, Vol.23 (4), p.85-85, Article 85

2021

Volltextzugriff (PDF)

Two-Stage Single-Compartment Models to Evaluate Dissolution in the Lower Intestine

Journal of pharmaceutical sciences, 2015-09, Vol.104 (9), p.2986-2997

2015

Volltextzugriff (PDF)

Possibilities and Limiting Factors for the Use of Dissolution as a Quality Control Tool to Detect Presence of Crystallinity for Amorphous Solid Dispersions: An Experimental and Modeling Investigation

Journal of pharmaceutical sciences, 2019-09, Vol.108 (9), p.3054-3062

2019

Volltextzugriff (PDF)

Dose Number as a Tool to Guide Lead Optimization for Orally Bioavailable Compounds in Drug Discovery

Journal of medicinal chemistry, 2022-02, Vol.65 (3), p.1685-1694

2022

Volltextzugriff (PDF)

Using Absorption Simulation and Gastric pH Modulated Dog Model for Formulation Development To Overcome Achlorhydria Effect

Molecular pharmaceutics, 2011-12, Vol.8 (6), p.2216-2223

2011

Volltextzugriff (PDF)

Integration of Precipitation Kinetics From an In Vitro, Multicompartment Transfer System and Mechanistic Oral Absorption Modeling for Pharmacokinetic Prediction of Weakly Basic Drugs

Journal of pharmaceutical sciences, 2019-01, Vol.108 (1), p.574-583

2019

Volltextzugriff (PDF)

Human intestinal fluid layer separation: The effect on colloidal structures & solubility of lipophilic compounds

European journal of pharmaceutics and biopharmaceutics, 2018-08, Vol.129, p.104-110

2018

Volltextzugriff (PDF)

1 – 25 von 39

Suche als RSS-Feed

Aktive Filter

KollektionOxford Journals

KollektionTaylor & Francis Journals Auto-Holdings Collection

PublikationsformDissertationen

ThemaLife Sciences & Biomedicine

ThemaSolubility

Suchergebnisse filtern

Filter anzeigen

Nur zeigen

Geprüft (Peer-Review)
(39)
Mit Volltextzugriff
(39)

Publikationsform

Artikel
(39)

Sprache

Englisch
(39)
Japanisch
(9)

Erscheinungsjahr

n.n

Thema

13 weitere anzeigen...

Weniger anzeigen...

Zeitschrift / Serie

3 weitere anzeigen...

Weniger anzeigen...

Menü

Weitere Dienste

Einstellungen

Physiologically Based Oral Absorption Modelling to Study Gut-Level Drug Interactions

Application of Absorption Modeling in Rational Design of Drug Product Under Quality-by-Design Paradigm

Understanding the Effect of API Properties on Bioavailability Through Absorption Modeling

Crystalline Nanosuspensions as Potential Toxicology and Clinical Oral Formulations for BCS II/IV Compounds

Establishing the Bioequivalence Safe Space for Immediate-Release Oral Dosage Forms using Physiologically Based Biopharmaceutics Modeling (PBBM): Case Studies

Assessment of food effects during clinical development

Amorphous Solid Dispersions or Prodrugs: Complementary Strategies to Increase Drug Absorption

The impact of reduced gastric acid secretion on dissolution of salts of weak bases in the fasted upper gastrointestinal lumen: Data in biorelevant media and in human aspirates

Physiologically Based Absorption Modeling for Amorphous Solid Dispersion Formulations

Food Effect Projections via Physiologically Based Pharmacokinetic Modeling: Predictive Case Studies

Utility of PBPK Absorption Modeling to Guide Modified Release Formulation Development of Gaboxadol, a Highly Soluble Compound With Region-Dependent Absorption

Development of In Vitro–In Vivo Correlation for Amorphous Solid Dispersion Immediate-Release Suvorexant Tablets and Application to Clinically Relevant Dissolution Specifications and In-Process Controls

Industry's View on Using Quality Control, Biorelevant, and Clinically Relevant Dissolution Tests for Pharmaceutical Development, Registration, and Commercialization

Physiologically based Pharmacokinetic Models under the Prism of the Finite Absorption Time Concept

An Extrusion Spheronization Approach to Enable a High Drug Load Formulation of a Poorly Soluble Drug with a Low Melting Surfactant

Forecasting in vivo oral absorption and food effect of micronized and nanosized aprepitant formulations in humans

Evaluation of Dissolution in the Lower Intestine and Its Impact on the Absorption Process of High Dose Low Solubility Drugs

Dissolution and Translational Modeling Strategies Enabling Patient-Centric Drug Product Development: the M-CERSI Workshop Summary Report

Use of Physiologically Based Pharmacokinetic Modeling for Predicting Drug–Food Interactions: Recommendations for Improving Predictive Performance of Low Confidence Food Effect Models

Two-Stage Single-Compartment Models to Evaluate Dissolution in the Lower Intestine

Possibilities and Limiting Factors for the Use of Dissolution as a Quality Control Tool to Detect Presence of Crystallinity for Amorphous Solid Dispersions: An Experimental and Modeling Investigation

Dose Number as a Tool to Guide Lead Optimization for Orally Bioavailable Compounds in Drug Discovery

Using Absorption Simulation and Gastric pH Modulated Dog Model for Formulation Development To Overcome Achlorhydria Effect

Integration of Precipitation Kinetics From an In Vitro, Multicompartment Transfer System and Mechanistic Oral Absorption Modeling for Pharmacokinetic Prediction of Weakly Basic Drugs

Human intestinal fluid layer separation: The effect on colloidal structures & solubility of lipophilic compounds

Aktive Filter

Suchergebnisse filtern