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Pan-PI3K inhibition with copanlisib overcomes Treg- and M2-TAM-mediated immune suppression and promotes anti-tumor immune responses

Clinical and experimental medicine, 2023-12, Vol.23 (8), p.5445-5461

2023

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Preclinical Antitumor Efficacy of BAY 1129980-a Novel Auristatin-Based Anti-C4.4A (LYPD3) Antibody-Drug Conjugate for the Treatment of Non-Small Cell Lung Cancer

Molecular cancer therapeutics, 2017-05, Vol.16 (5), p.893-904

2017

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Cytochrome c Maintains Mitochondrial Transmembrane Potential and ATP Generation after Outer Mitochondrial Membrane Permeabilization during the Apoptotic Process

The Journal of cell biology, 2001-04, Vol.153 (2), p.319-328

2001

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Preservation of Mitochondrial Structure and Function after Bid- or Bax-Mediated Cytochrome c Release

The Journal of cell biology, 2000-09, Vol.150 (5), p.1027-1036

2000

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Global Transcriptome Analysis of Genetically Identified Neurons in the Adult Cortex

The Journal of neuroscience, 2006-09, Vol.26 (39), p.9956-9966

2006

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Modular Assembly of Allosteric MEK Inhibitor Structural Elements Unravels Potency and Feedback-Modulation Handles

ChemMedChem, 2015-12, Vol.10 (12), p.2004-2013

2015

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Inhibition of the IL-2-inducible tyrosine kinase (Itk) activity: a new concept for the therapy of inflammatory skin diseases

Experimental dermatology, 2011-01, Vol.20 (1), p.41-47

2011

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A miniaturized high-throughput screening assay for fucosyltransferase VII

Analytical biochemistry, 2008, Vol.372 (1), p.96-105

2008

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Preclinical Efficacy of a PSMA-Targeted Thorium-227 Conjugate (PSMA-TTC), a Targeted Alpha Therapy for Prostate Cancer

Clinical cancer research, 2020-04, Vol.26 (8), p.1985-1996

2020

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Identification of regulated genes during permanent focal cerebral ischaemia: characterization of the protein kinase 9b5/MARKL1/MARK4

Journal of neurochemistry, 2004-03, Vol.88 (5), p.1114-1126

2004

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Novel Mps1 Kinase Inhibitors with Potent Antitumor Activity

Molecular cancer therapeutics, 2016-04, Vol.15 (4), p.583-592

2016

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Inhibition of BUB1 Kinase by BAY 1816032 Sensitizes Tumor Cells toward Taxanes, ATR, and PARP Inhibitors In Vitro and In Vivo

Clinical cancer research, 2019-02, Vol.25 (4), p.1404-1414

2019

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Restriction-mediated Differential Display (RMDD) Identifies pip92 as a Pro-apoptotic Gene Product Induced During Focal Cerebral Ischemia

Journal of cerebral blood flow and metabolism, 2004-02, Vol.24 (2), p.224-236

2004

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Endometriosis Leads to an Increased Trefoil Factor 3 Concentration in the Peritoneal Cavity but Does Not Alter Systemic Levels

Reproductive sciences (Thousand Oaks, Calif.), 2017-02, Vol.24 (2), p.258-267

2017

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Cancer therapy monitoring in xenografts by quantitative analysis of circulating tumor DNA

Biomarkers, 2012-09, Vol.17 (6), p.498-506

2012

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Preclinical evaluation of biomarkers for response monitoring to the MET inhibitor BAY-853474

Biomarkers, 2012-06, Vol.17 (4), p.325-335

2012

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Preclinical Evaluation of a Novel c-Met Inhibitor in a Gastric Cancer Xenograft Model Using Small Animal PET

Molecular imaging and biology, 2013-04, Vol.15 (2), p.203-211

2013

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TorsinA protects against oxidative stress in COS-1 and PC12 cells

Neuroscience letters, 2003-10, Vol.350 (3), p.153-156

2003

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[16] Cell-free apoptosis in Xenopus laevis egg extracts

Methods in Enzymology, 2000, Vol.322, p.183-198

2000

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The chaperonin cycle cannot substitute for prolyl isomerase activity, but GroEL alone promotes productive folding of a cyclophilin-sensitive substrate to a cyclophilin-resistant form

The EMBO journal, 1997-08, Vol.16 (15), p.4568-4578

1997

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Cyclophilin-promoted folding of mouse dihydrofolate reductase does not include the slow conversion of the late-folding intermediate to the active enzyme

Journal of molecular biology, 2000-03, Vol.297 (3), p.809-818

2000

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Pan-PI3K inhibition with copanlisib overcomes Treg- and M2-TAM-mediated immune suppression and promotes anti-tumor immune responses

Preclinical Antitumor Efficacy of BAY 1129980-a Novel Auristatin-Based Anti-C4.4A (LYPD3) Antibody-Drug Conjugate for the Treatment of Non-Small Cell Lung Cancer

Cytochrome c Maintains Mitochondrial Transmembrane Potential and ATP Generation after Outer Mitochondrial Membrane Permeabilization during the Apoptotic Process

Preservation of Mitochondrial Structure and Function after Bid- or Bax-Mediated Cytochrome c Release

Global Transcriptome Analysis of Genetically Identified Neurons in the Adult Cortex

Modular Assembly of Allosteric MEK Inhibitor Structural Elements Unravels Potency and Feedback-Modulation Handles

Inhibition of the IL-2-inducible tyrosine kinase (Itk) activity: a new concept for the therapy of inflammatory skin diseases

A miniaturized high-throughput screening assay for fucosyltransferase VII

Preclinical Efficacy of a PSMA-Targeted Thorium-227 Conjugate (PSMA-TTC), a Targeted Alpha Therapy for Prostate Cancer

Identification of regulated genes during permanent focal cerebral ischaemia: characterization of the protein kinase 9b5/MARKL1/MARK4

Novel Mps1 Kinase Inhibitors with Potent Antitumor Activity

Inhibition of BUB1 Kinase by BAY 1816032 Sensitizes Tumor Cells toward Taxanes, ATR, and PARP Inhibitors In Vitro and In Vivo

Restriction-mediated Differential Display (RMDD) Identifies pip92 as a Pro-apoptotic Gene Product Induced During Focal Cerebral Ischemia

Endometriosis Leads to an Increased Trefoil Factor 3 Concentration in the Peritoneal Cavity but Does Not Alter Systemic Levels

Cancer therapy monitoring in xenografts by quantitative analysis of circulating tumor DNA

Preclinical evaluation of biomarkers for response monitoring to the MET inhibitor BAY-853474

Preclinical Evaluation of a Novel c-Met Inhibitor in a Gastric Cancer Xenograft Model Using Small Animal PET

TorsinA protects against oxidative stress in COS-1 and PC12 cells

[16] Cell-free apoptosis in Xenopus laevis egg extracts

The chaperonin cycle cannot substitute for prolyl isomerase activity, but GroEL alone promotes productive folding of a cyclophilin-sensitive substrate to a cyclophilin-resistant form

Cyclophilin-promoted folding of mouse dihydrofolate reductase does not include the slow conversion of the late-folding intermediate to the active enzyme

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