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Early Oligodendrocyte/Myelin Pathology in Alzheimer's Disease Mice Constitutes a Novel Therapeutic Target

The American journal of pathology, 2010-09, Vol.177 (3), p.1422-1435

2010

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SIRT6 protects against endothelial dysfunction and atherosclerosis in mice

Aging (Albany, NY.), 2016-05, Vol.8 (5), p.1064-1082

2016

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Triple-transgenic Alzheimer's disease mice exhibit region-specific abnormalities in brain myelination patterns prior to appearance of amyloid and tau pathology

Glia, 2009-01, Vol.57 (1), p.54-65

2009

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Chronic Neuron-Specific Tumor Necrosis Factor-Alpha Expression Enhances the Local Inflammatory Environment Ultimately Leading to Neuronal Death in 3xTg-AD Mice

The American journal of pathology, 2008-12, Vol.173 (6), p.1768-1782

2008

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Early correlation of microglial activation with enhanced tumor necrosis factor-alpha and monocyte chemoattractant protein-1 expression specifically within the entorhinal cortex of triple transgenic Alzheimer's disease mice

Journal of neuroinflammation, 2005-10, Vol.2 (1), p.23-23, Article 23

2005

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Neuronal precursor-restricted transduction via in utero CNS gene delivery of a novel bipartite HSV amplicon/transposase hybrid vector

Molecular therapy, 2006-03, Vol.13 (3), p.580-588

2006

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Ablation of TNF-RI/RII Expression in Alzheimer's Disease Mice Leads to an Unexpected Enhancement of Pathology: Implications for Chronic Pan-TNF-α Suppressive Therapeutic Strategies in the Brain

The American journal of pathology, 2011-10, Vol.179 (4), p.2053-2070

2011

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Interferon-γ Differentially Affects Alzheimer’s Disease Pathologies and Induces Neurogenesis in Triple Transgenic-AD Mice

The American journal of pathology, 2009-11, Vol.175 (5), p.2076-2088

2009

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Herpes simplex virus/Sleeping Beauty vector-based embryonic gene transfer using the HSB5 mutant: loss of apparent transposition hyperactivity in vivo

Human gene therapy, 2010-11, Vol.21 (11), p.1603-1613

2010

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Chronic Neuron- and Age-Selective Down-Regulation of TNF Receptor Expression in Triple-Transgenic Alzheimer Disease Mice Leads to Significant Modulation of Amyloid- and Tau-Related Pathologies

The American journal of pathology, 2013-06, Vol.182 (6), p.2285-2297

2013

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Neuronal Specificity of HSV/Sleeping Beauty Amplicon Transduction In Utero Is Driven Primarily by Tropism and Cell Type Composition

Molecular therapy, 2007-10, Vol.15 (10), p.1848-1855

2007

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Novel Thrombotic Function of a Human SNP in STXBP5 Revealed by CRISPR/Cas9 Gene Editing in Mice

Arteriosclerosis, thrombosis, and vascular biology, 2017-02, Vol.37 (2), p.264-270

2017

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Acetylcholine Inhibits Platelet Activation

The Journal of pharmacology and experimental therapeutics, 2019-05, Vol.369 (2), p.182-187

2019

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Helper-free HSV-1 Amplicons Elicit a Markedly Less Robust Innate Immune Response in the CNS

Molecular therapy, 2003-02, Vol.7 (2), p.218-227

2003

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Aβ-directed Single-chain Antibody Delivery Via a Serotype-1 AAV Vector Improves Learning Behavior and Pathology in Alzheimer's Disease Mice

Molecular therapy, 2010-08, Vol.18 (8), p.1471-1481

2010

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The Last Chapter

Seminars in oncology, 2015-12, Vol.42 (6), p.923-924

2015

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Reduced Pathology and Improved Behavioral Performance in Alzheimer's Disease Mice Vaccinated With HSV Amplicons Expressing Amyloid-β and Interleukin-4

Molecular therapy, 2008-05, Vol.16 (5), p.845-853

2008

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Generating Differentially Targeted Amyloid-β Specific Intrabodies as a Passive Vaccination Strategy for Alzheimer's Disease

Molecular therapy, 2009-12, Vol.17 (12), p.2031-2040

2009

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Biochemical and morphological characterization of the AβPP/PS/tau triple transgenic mouse model and its relevance to sporadic Alzheimer's disease

Journal of Alzheimer's disease, 2011-01, Vol.27 (2), p.361-376

2011

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Ablation of TNF-RI/RII Expression in Alzheimer's Disease Mice Leads to an Unexpected Enhancement of Pathology

The American journal of pathology, 2011, Vol.179 (4), p.2053-2070

2011

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HSV amplicon-mediated Aβ vaccination in Tg2576 mice: differential antigen-specific immune responses

Neurobiology of aging, 2005-04, Vol.26 (4), p.393-407

2005

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Ablated TNF receptor expression differentially affects microglial activation and amyloid deposition in the 3xTg-AD mouse model

Alzheimer's & dementia, 2010-07, Vol.6 (4), p.S265-S266

2010

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Genome-Wide Association Transethnic Meta-Analyses Identifies Novel Associations Regulating Coagulation Factor VIII and von Willebrand Factor Plasma Levels

Circulation (New York, N.Y.), 2019-01, Vol.139 (5), p.620-635

2019

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Oligodendrocyte cell lineage represents an amyloid beta 1-42 sensitive cell population leading to white matter alterations during early Alzheimer's disease

Alzheimer's & dementia, 2010-07, Vol.6 (4), p.S385-S385

2010

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Early Oligodendrocyte/Myelin Pathology in Alzheimer's Disease Mice Constitutes a Novel Therapeutic Target

SIRT6 protects against endothelial dysfunction and atherosclerosis in mice

Triple-transgenic Alzheimer's disease mice exhibit region-specific abnormalities in brain myelination patterns prior to appearance of amyloid and tau pathology

Chronic Neuron-Specific Tumor Necrosis Factor-Alpha Expression Enhances the Local Inflammatory Environment Ultimately Leading to Neuronal Death in 3xTg-AD Mice

Early correlation of microglial activation with enhanced tumor necrosis factor-alpha and monocyte chemoattractant protein-1 expression specifically within the entorhinal cortex of triple transgenic Alzheimer's disease mice

Neuronal precursor-restricted transduction via in utero CNS gene delivery of a novel bipartite HSV amplicon/transposase hybrid vector

Ablation of TNF-RI/RII Expression in Alzheimer's Disease Mice Leads to an Unexpected Enhancement of Pathology: Implications for Chronic Pan-TNF-α Suppressive Therapeutic Strategies in the Brain

Interferon-γ Differentially Affects Alzheimer’s Disease Pathologies and Induces Neurogenesis in Triple Transgenic-AD Mice

Herpes simplex virus/Sleeping Beauty vector-based embryonic gene transfer using the HSB5 mutant: loss of apparent transposition hyperactivity in vivo

Chronic Neuron- and Age-Selective Down-Regulation of TNF Receptor Expression in Triple-Transgenic Alzheimer Disease Mice Leads to Significant Modulation of Amyloid- and Tau-Related Pathologies

Neuronal Specificity of HSV/Sleeping Beauty Amplicon Transduction In Utero Is Driven Primarily by Tropism and Cell Type Composition

Novel Thrombotic Function of a Human SNP in STXBP5 Revealed by CRISPR/Cas9 Gene Editing in Mice

Acetylcholine Inhibits Platelet Activation

Helper-free HSV-1 Amplicons Elicit a Markedly Less Robust Innate Immune Response in the CNS

Aβ-directed Single-chain Antibody Delivery Via a Serotype-1 AAV Vector Improves Learning Behavior and Pathology in Alzheimer's Disease Mice

The Last Chapter

Reduced Pathology and Improved Behavioral Performance in Alzheimer's Disease Mice Vaccinated With HSV Amplicons Expressing Amyloid-β and Interleukin-4

Interleukin-17 limits hypoxia-inducible factor 1α and development of hypoxic granulomas during tuberculosis

Generating Differentially Targeted Amyloid-β Specific Intrabodies as a Passive Vaccination Strategy for Alzheimer's Disease

Biochemical and morphological characterization of the AβPP/PS/tau triple transgenic mouse model and its relevance to sporadic Alzheimer's disease

Ablation of TNF-RI/RII Expression in Alzheimer's Disease Mice Leads to an Unexpected Enhancement of Pathology

HSV amplicon-mediated Aβ vaccination in Tg2576 mice: differential antigen-specific immune responses

Ablated TNF receptor expression differentially affects microglial activation and amyloid deposition in the 3xTg-AD mouse model

Genome-Wide Association Transethnic Meta-Analyses Identifies Novel Associations Regulating Coagulation Factor VIII and von Willebrand Factor Plasma Levels

Oligodendrocyte cell lineage represents an amyloid beta 1-42 sensitive cell population leading to white matter alterations during early Alzheimer's disease

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