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Identification of WP1066, an inhibitor of JAK2 and STAT3, as a K V 1.3 potassium channel blocker

British journal of pharmacology, 2021-07, Vol.178 (13), p.2617-2631

2021

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Discovery of K V 1.3 ion channel inhibitors: Medicinal chemistry approaches and challenges

Medicinal research reviews, 2021-07, Vol.41 (4), p.2423-2473

2021

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A new negative allosteric modulator, AP14145, for the study of small conductance calcium‐activated potassium (KCa2) channels

British journal of pharmacology, 2017-12, Vol.174 (23), p.4396-4408

2017

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Mechanism of inhibition of mouse Slo3 (KCa5.1) potassium channels by quinine, quinidine and barium

British journal of pharmacology, 2015-09, Vol.172 (17), p.4355-4363

2015

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The role of activation of KАTP channels on hydrogen sulfide induced renoprotective effect on diabetic nephropathy

Journal of cellular physiology, 2020-06, Vol.235 (6), p.5223-5228

2020

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Modeling of the hERG K+ Channel Blockage Using Online Chemical Database and Modeling Environment (OCHEM)

Molecular informatics, 2017-12, Vol.36 (12), p.n/a

2017

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Negative feedback regulation of vasocontraction by potassium channels in 10- to 15-day-old rats: Dominating role of K v 7 channels

Acta Physiologica, 2019-02, Vol.225 (2), p.e13176

2019

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4-Aminopyridine: a pan voltage-gated potassium channel inhibitor that enhances K v 7.4 currents and inhibits noradrenaline-mediated contraction of rat mesenteric small arteries

British journal of pharmacology, 2018-02, Vol.175 (3), p.501-516

2018

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UDP-glucose enhances outward K+ currents necessary for cell differentiation and stimulates cell migration by activating the GPR17 receptor in oligodendrocyte precursors

Glia, 2013-07, Vol.61 (7), p.1155-1171

2013

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Post-transcriptional regulation of GORK channels by superoxide anion contributes to increases in outward-rectifying K+ currents

The New phytologist, 2013-06, Vol.198 (4), p.1039-1048

2013

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Large-conductance Ca 2+ -activated K + channel activation by apical P2Y receptor agonists requires hydrocortisone in differentiated airway epithelium

The Journal of physiology, 2017-07, Vol.595 (14), p.4631-4645

2017

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Upregulation of K2P5.1 potassium channels in multiple sclerosis

Annals of neurology, 2010-07, Vol.68 (1), p.58-69

2010

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SDF-1α and LPA modulate microglia potassium channels through rho gtpases to regulate cell morphology

Glia, 2013-10, Vol.61 (10), p.1620-1628

2013

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G protein‐gated inwardly rectifying potassium (KIR3) channels play a primary role in the antinociceptive effect of oxycodone, but not morphine, at supraspinal sites

British journal of pharmacology, 2014-01, Vol.171 (1), p.253-264

2014

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KATP channels in the nodose ganglia mediate the orexigenic actions of ghrelin

The Journal of physiology, 2015-09, Vol.593 (17), p.3973-3989

2015

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KATP channel openers: Structure-activity relationships and therapeutic potential

Medicinal research reviews, 2004-03, Vol.24 (2), p.213-266

Mannhold, Raimund

2004

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Calcium-activated BK Ca channels govern dynamic membrane depolarizations of horizontal cells in rodent retina

The Journal of physiology, 2017-07, Vol.595 (13), p.4449-4465

2017

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Matrix volume measurements challenge the existence of diazoxide/glibencamide-sensitive KATP channels in rat mitochondria

The Journal of physiology, 2003-03, Vol.547 (3), p.893-902

2003

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Cardioprotection afforded by chronic exercise is mediated by the sarcolemmal, and not the mitochondrial, isoform of the KATP channel in the rat

The Journal of physiology, 2005-12, Vol.569 (3), p.913-924

2005

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BK channel β1 subunits regulate airway contraction secondary to M2 muscarinic acetylcholine receptor mediated depolarization

The Journal of physiology, 2011-04, Vol.589 (7), p.1803-1817

2011

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The insulin sensitizing effect of topiramate involves KATP channel activation in the central nervous system

British journal of pharmacology, 2013-10, Vol.170 (4), p.908-918

2013

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Functional expression of Kir4.1 channels in spinal cord astrocytes

Glia, 2006-04, Vol.53 (5), p.516-528

2006

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Na(+) -Ca(2+) Exchanger, Leak K(+) Channel and Hyperpolarization-Activated Cyclic Nucleotide-Gated Channel Comediate the Histamine-Induced Excitation on Rat Inferior Vestibular Nucleus Neurons

CNS neuroscience & therapeutics, 2016-03, Vol.22 (3), p.184-193

2016

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Heterogeneous effects of antiepileptic drugs in an in vitro epilepsy model - a functional multineuron calcium imaging study

The European journal of neuroscience, 2015-07, Vol.42 (2), p.1818-1829

2015

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Mechanisms of zolpidem‐induced long QT syndrome: acute inhibition of recombinant hERG K+ channels and action potential prolongation in human cardiomyocytes derived from induced pluripotent stem cells

British journal of pharmacology, 2013-03, Vol.168 (5), p.1215-1229

2013

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Identification of WP1066, an inhibitor of JAK2 and STAT3, as a K V 1.3 potassium channel blocker

Discovery of K V 1.3 ion channel inhibitors: Medicinal chemistry approaches and challenges

A new negative allosteric modulator, AP14145, for the study of small conductance calcium‐activated potassium (KCa2) channels

Mechanism of inhibition of mouse Slo3 (KCa5.1) potassium channels by quinine, quinidine and barium

The role of activation of KАTP channels on hydrogen sulfide induced renoprotective effect on diabetic nephropathy

Modeling of the hERG K+ Channel Blockage Using Online Chemical Database and Modeling Environment (OCHEM)

Negative feedback regulation of vasocontraction by potassium channels in 10- to 15-day-old rats: Dominating role of K v 7 channels

4-Aminopyridine: a pan voltage-gated potassium channel inhibitor that enhances K v 7.4 currents and inhibits noradrenaline-mediated contraction of rat mesenteric small arteries

UDP-glucose enhances outward K+ currents necessary for cell differentiation and stimulates cell migration by activating the GPR17 receptor in oligodendrocyte precursors

Post-transcriptional regulation of GORK channels by superoxide anion contributes to increases in outward-rectifying K+ currents

Large-conductance Ca 2+ -activated K + channel activation by apical P2Y receptor agonists requires hydrocortisone in differentiated airway epithelium

Upregulation of K2P5.1 potassium channels in multiple sclerosis

SDF-1α and LPA modulate microglia potassium channels through rho gtpases to regulate cell morphology

G protein‐gated inwardly rectifying potassium (KIR3) channels play a primary role in the antinociceptive effect of oxycodone, but not morphine, at supraspinal sites

KATP channels in the nodose ganglia mediate the orexigenic actions of ghrelin

KATP channel openers: Structure-activity relationships and therapeutic potential

Calcium-activated BK Ca channels govern dynamic membrane depolarizations of horizontal cells in rodent retina

Matrix volume measurements challenge the existence of diazoxide/glibencamide-sensitive KATP channels in rat mitochondria

Cardioprotection afforded by chronic exercise is mediated by the sarcolemmal, and not the mitochondrial, isoform of the KATP channel in the rat

BK channel β1 subunits regulate airway contraction secondary to M2 muscarinic acetylcholine receptor mediated depolarization

The insulin sensitizing effect of topiramate involves KATP channel activation in the central nervous system

Functional expression of Kir4.1 channels in spinal cord astrocytes

Na(+) -Ca(2+) Exchanger, Leak K(+) Channel and Hyperpolarization-Activated Cyclic Nucleotide-Gated Channel Comediate the Histamine-Induced Excitation on Rat Inferior Vestibular Nucleus Neurons

Heterogeneous effects of antiepileptic drugs in an in vitro epilepsy model - a functional multineuron calcium imaging study

Mechanisms of zolpidem‐induced long QT syndrome: acute inhibition of recombinant hERG K+ channels and action potential prolongation in human cardiomyocytes derived from induced pluripotent stem cells

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