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1,1-Diarylalkenes as anticancer agents: Dual inhibitors of tubulin polymerization and phosphodiesterase 4

Bioorganic & medicinal chemistry, 2011-11, Vol.19 (21), p.6356-6374

2011

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1-[2-(2-Benzoyl- and 2-benzylphenoxy)ethyl]uracils as potent anti-HIV-1 agents

Bioorganic & medicinal chemistry, 2011-10, Vol.19 (19), p.5794-5802

2011

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1,2,3-Selenadiazole thioacetanilides: Synthesis and anti-HIV activity evaluation

Bioorganic & medicinal chemistry, 2009-09, Vol.17 (17), p.6374-6379

2009

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1,2,3-Triazole-, arylamino- and thio-substituted 1,4-naphthoquinones: Potent antitumor activity, electrochemical aspects, and bioisosteric replacement of C-ring-modified lapachones

Bioorganic & medicinal chemistry, 2014-03, Vol.22 (5), p.1608-1619

2014

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1,2,4-Triazolyl octahydropyrrolo[2,3-b]pyrroles: A new series of potent and selective dopamine D3 receptor antagonists

Bioorganic & medicinal chemistry, 2016-04, Vol.24 (8), p.1619-1636

2016

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1,2-Benzothiazine 1,1-dioxide carboxylate derivatives as novel potent inhibitors of aldose reductase

Bioorganic & medicinal chemistry, 2011-12, Vol.19 (23), p.7262-7269

2011

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1-(2-Carboxyindol-5-yloxy)propan-2-ones as inhibitors of human cytosolic phospholipase A2alpha: synthesis, biological activity, metabolic stability, and solubility

Bioorganic & medicinal chemistry, 2008-04, Vol.16 (7), p.3489-3500

2008

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1-(2-Phenoxyphenyl)methanamines: SAR for dual serotonin/noradrenaline reuptake inhibition, metabolic stability and hERG affinity

Bioorganic & medicinal chemistry, 2008-01, Vol.18 (2), p.596-599

2008

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1,3,7-Triethyl-substituted xanthines—possess nanomolar affinity for the adenosine A1 receptor

Bioorganic & medicinal chemistry, 2015-10, Vol.23 (20), p.6641-6649

2015

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1-, 3-and 8-substituted-9-deazaxanthines as potent and selective antagonists at the human A2B adenosine receptor

Bioorganic & medicinal chemistry, 2008-03, Vol.16 (6), p.2852-2869

2008

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1,3-Azoles from ortho-naphthoquinones: Synthesis of aryl substituted imidazoles and oxazoles and their potent activity against Mycobacterium tuberculosis

Bioorganic & medicinal chemistry, 2012-11, Vol.20 (21), p.6482-6488

2012

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1,3-Dialkyl-8-(hetero)aryl-9-OH-9-deazaxanthines as potent A2B adenosine receptor antagonists : Design, synthesis, structure-affinity and structure-selectivity relationships

Bioorganic & medicinal chemistry, 2008-11, Vol.16 (22), p.9780-9789

2008

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1,3-Diphenyl-1H-pyrazole derivatives as a new series of potent PPARγ partial agonists

Bioorganic & medicinal chemistry, 2010-12, Vol.18 (23), p.8315-8323

2010

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1,3-Dipropyl-8-(1-phenylacetamide-1 H-pyrazol-3-yl)-xanthine derivatives as highly potent and selective human A 2B adenosine receptor antagonists

Bioorganic & medicinal chemistry, 2008, Vol.16 (5), p.2419-2430

2008

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1,3-Dipropyl-8-(1-phenylacetamide-1H-pyrazol-3-yl)-xanthine derivatives as highly potent and selective human A(2B) adenosine receptor antagonists

Bioorganic & medicinal chemistry, 2008-03, Vol.16 (5), p.2419-2430

2008

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1,3-Dipropyl-8-(1 -phenylacetamide-1Η-pyrazol-3-yl)-xanthine derivatives as highly potent and selective human A2B adenosine receptor antagonists

Bioorganic & medicinal chemistry, 2008-03, Vol.16 (5), p.2419-2430

2008

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1-[4-(2-Aminoethoxy)phenylcarbonyl]-3,5-bis-(benzylidene)-4-oxopiperidines: A novel series of highly potent revertants of P-glycoprotein associated multidrug resistance

Bioorganic & medicinal chemistry, 2008-06, Vol.18 (12), p.3484-3487

2008

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1,4,9,10-Anthradiquinone as precursor for antitumor compounds

Bioorganic & medicinal chemistry, 2006-05, Vol.14 (10), p.3599-3614

2006

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1,4-Disubstituted aromatic piperazines with high 5-HT2A/D2 selectivity: Quantitative structure-selectivity investigations, docking, synthesis and biological evaluation

Bioorganic & medicinal chemistry, 2015-09, Vol.23 (18), p.6195-6209

2015

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1-(5-Carboxy- and 5-carbamoylindol-1-yl)propan-2-ones as inhibitors of human cytosolic phospholipase A2alpha: bioisosteric replacement of the carboxylic acid and carboxamide moiety

Bioorganic & medicinal chemistry, 2007-04, Vol.15 (8), p.2883-2891

2007

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1,5-Dihydro-benzo[ e][1,4]oxazepin-2( 1H)-ones containing a 7-(5′-cyanopyrrol-2-yl) group as nonsteroidal progesterone receptor modulators

Bioorganic & medicinal chemistry, 2008-09, Vol.18 (18), p.5015-5017

2008

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1,5-Disubstituted 1,2,3-triazoles as cis-restricted analogues of combretastatin A-4: Synthesis, molecular modeling and evaluation as cytotoxic agents and inhibitors of tubulin

Bioorganic & medicinal chemistry, 2008-05, Vol.16 (9), p.4829-4838

2008

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1,6-Bis[(benzyloxy)methyl]uracil derivatives—Novel antivirals with activity against HIV-1 and influenza H1N1 virus

Bioorganic & medicinal chemistry, 2016-06, Vol.24 (11), p.2476-2485

2016

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1-Aryl-2-dimethylaminomethyl-2-propen-1-one hydrochlorides and related adducts: A quest for selective cytotoxicity for malignant cells

Bioorganic & medicinal chemistry, 2008-05, Vol.16 (10), p.5747-5753

2008

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1-Aryl-tetrahydroisoquinoline analogs as active anti-HIV agents in vitro

Bioorganic & medicinal chemistry, 2008-04, Vol.18 (7), p.2475-2478

2008

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1 – 25 von 5.333

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1,1-Diarylalkenes as anticancer agents: Dual inhibitors of tubulin polymerization and phosphodiesterase 4

1-[2-(2-Benzoyl- and 2-benzylphenoxy)ethyl]uracils as potent anti-HIV-1 agents

1,2,3-Selenadiazole thioacetanilides: Synthesis and anti-HIV activity evaluation

1,2,3-Triazole-, arylamino- and thio-substituted 1,4-naphthoquinones: Potent antitumor activity, electrochemical aspects, and bioisosteric replacement of C-ring-modified lapachones

1,2,4-Triazolyl octahydropyrrolo[2,3-b]pyrroles: A new series of potent and selective dopamine D3 receptor antagonists

1,2-Benzothiazine 1,1-dioxide carboxylate derivatives as novel potent inhibitors of aldose reductase

1-(2-Carboxyindol-5-yloxy)propan-2-ones as inhibitors of human cytosolic phospholipase A2alpha: synthesis, biological activity, metabolic stability, and solubility

1-(2-Phenoxyphenyl)methanamines: SAR for dual serotonin/noradrenaline reuptake inhibition, metabolic stability and hERG affinity

1,3,7-Triethyl-substituted xanthines—possess nanomolar affinity for the adenosine A1 receptor

1-, 3-and 8-substituted-9-deazaxanthines as potent and selective antagonists at the human A2B adenosine receptor

1,3-Azoles from ortho-naphthoquinones: Synthesis of aryl substituted imidazoles and oxazoles and their potent activity against Mycobacterium tuberculosis

1,3-Dialkyl-8-(hetero)aryl-9-OH-9-deazaxanthines as potent A2B adenosine receptor antagonists : Design, synthesis, structure-affinity and structure-selectivity relationships

1,3-Diphenyl-1H-pyrazole derivatives as a new series of potent PPARγ partial agonists

1,3-Dipropyl-8-(1-phenylacetamide-1 H-pyrazol-3-yl)-xanthine derivatives as highly potent and selective human A 2B adenosine receptor antagonists

1,3-Dipropyl-8-(1-phenylacetamide-1H-pyrazol-3-yl)-xanthine derivatives as highly potent and selective human A(2B) adenosine receptor antagonists

1,3-Dipropyl-8-(1 -phenylacetamide-1Η-pyrazol-3-yl)-xanthine derivatives as highly potent and selective human A2B adenosine receptor antagonists

1-[4-(2-Aminoethoxy)phenylcarbonyl]-3,5-bis-(benzylidene)-4-oxopiperidines: A novel series of highly potent revertants of P-glycoprotein associated multidrug resistance

1,4,9,10-Anthradiquinone as precursor for antitumor compounds

1,4-Disubstituted aromatic piperazines with high 5-HT2A/D2 selectivity: Quantitative structure-selectivity investigations, docking, synthesis and biological evaluation

1-(5-Carboxy- and 5-carbamoylindol-1-yl)propan-2-ones as inhibitors of human cytosolic phospholipase A2alpha: bioisosteric replacement of the carboxylic acid and carboxamide moiety

1,5-Dihydro-benzo[ e][1,4]oxazepin-2( 1H)-ones containing a 7-(5′-cyanopyrrol-2-yl) group as nonsteroidal progesterone receptor modulators

1,5-Disubstituted 1,2,3-triazoles as cis-restricted analogues of combretastatin A-4: Synthesis, molecular modeling and evaluation as cytotoxic agents and inhibitors of tubulin

1,6-Bis[(benzyloxy)methyl]uracil derivatives—Novel antivirals with activity against HIV-1 and influenza H1N1 virus

1-Aryl-2-dimethylaminomethyl-2-propen-1-one hydrochlorides and related adducts: A quest for selective cytotoxicity for malignant cells

1-Aryl-tetrahydroisoquinoline analogs as active anti-HIV agents in vitro

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