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Discovery of a Potent, Orally Available, and Isoform-Selective Retinoic Acid β2 Receptor Agonist

Journal of medicinal chemistry, 2005-12, Vol.48 (24), p.7517-7519

2005

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Pimavanserin, a selective serotonin (5-HT)2A-inverse agonist, enhances the efficacy and safety of risperidone, 2 mg/day, but does not enhance efficacy of haloperidol, 2 mg/day: Comparison with reference dose risperidone, 6 mg/day

Schizophrenia research, 2012-11, Vol.141 (2), p.144-152

2012

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Discovery of an Ectopic Activation Site on the M 1 Muscarinic Receptor

Molecular pharmacology, 2002-06, Vol.61 (6), p.1297-1302

2002

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1 The Chemistry and Biochemistry of C-Nucleosides and C-Arylglycosides

Progress in Medicinal Chemistry, 1985, Vol.22, p.1-65

1985

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Constitutively Active Mutants of the Histamine H 1 Receptor Suggest a Conserved Hydrophobic Asparagine-Cage That Constrains the Activation of Class A G Protein-Coupled Receptors

Molecular pharmacology, 2008-01, Vol.73 (1), p.94-103

2008

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Atropisomeric Derivatives of 2‘,6‘-Disubstituted (R)-11-Phenylaporphine: Selective Serotonin 5-HT7 Receptor Antagonists

Journal of medicinal chemistry, 2001-04, Vol.44 (9), p.1337-1340

2001

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Pharmacology of polymorphic variants of the human 5-HT 1A receptor

Biochemical pharmacology, 2004, Vol.67 (3), p.479-490

2004

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Atropisomeric Derivatives of 2‘,6‘-Disubstituted ( R )-11-Phenylaporphine: Selective Serotonin 5-HT 7 Receptor Antagonists

Journal of medicinal chemistry, 2001-04, Vol.44 (9), p.1337-1340

2001

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Characterization of the Binding Site of the Histamine H 3 Receptor. 1. Various Approaches to the Synthesis of 2-(1 H -Imidazol-4-yl)cyclopropylamine and Histaminergic Activity of (1 R ,2 R )- and (1 S ,2 S )-2-(1 H -Imidazol-4-yl)- cyclopropylamine

Journal of medicinal chemistry, 1999-04, Vol.42 (7), p.1115-1122

1999

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Discovery of an Ectopic Activation Site on the M1Muscarinic Receptor

Molecular pharmacology, 2002-06, Vol.61 (6), p.1297

2002

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Intramolecular Transfer of CO from (.eta.6-arene)Cr(CO)3 Complexes in Stille-Type Palladium-Catalyzed Cross-Coupling Reactions

Organometallics, 1995-08, Vol.14 (8), p.3897-3900

1995

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Animal Carotenoids. 32. Carotenoids of Mytilus edulis (Edible Mussel)

Acta chemica Scandinavica (Copenhagen. 1989), 1988, Vol.42b, p.495-503

1988

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Interactions of ligands with active and inactive conformations of the dopamine D 2 receptor

European journal of pharmacology, 1998-04, Vol.346 (2), p.299-307

1998

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Derivatives of 2-arylcyclopropylamine: Synthesis and interactions with 5-HT 1A receptors

Bioorganic & medicinal chemistry letters, 1996, Vol.6 (4), p.415-420

1996

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trans-2-Aryl-N,N-dipropylcyclopropylamines: Synthesis and Interactions with 5-HT1A Receptors

Journal of medicinal chemistry, 1996-03, Vol.39 (7), p.1485-1493

1996

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Stereoselective palladium-catalyzed cyclopropanation of α,β-unsaturated carboxylic acids derivatized with oppolzer's sultam

Tetrahedron letters, 1991-09, Vol.32 (40), p.5625-5628

1991

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3-Lithioquinuclidin-2-ene: A novel intermediate for the synthesis of muscarinic agonists and antagonists

Bioorganic & medicinal chemistry letters, 1994-12, Vol.4 (24), p.2837-2840

1994

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Novel derivatives of 3-(dipropylamino)chroman. Interactions with 5-HT 1A and D 2A receptors

Bioorganic & medicinal chemistry letters, 1999, Vol.9 (11), p.1583-1586

1999

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Palladium catalyzed syntheses of phenyl-substittuted pgf2α analogues: potential antigluaucoma agents

Bioorganic & medicinal chemistry letters, 1993-02, Vol.3 (2), p.241-244

1993

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Ligand-controlled palladium-catalyzed intramolecular reactions of phenyl-substituted prostaglandin F2 α analogues

Tetrahedron, 1995-08, Vol.51 (33), p.9139-9154

1995

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Derivatives of 2-arylcyclopropylamine: Synthesis and interactions with 5-HT1A receptors

Bioorganic & medicinal chemistry letters, 1996-02, Vol.6 (4), p.415-420

1996

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Chemical genomics: massively parallel technologies for rapid lead identification and target validation

Cytotechnology (Dordrecht), 2002, Vol.38 (1-3), p.3-10

2002

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Derivatives of 17-Phenyl-18,19,20-trinorprostaglandin F2.alpha. Isopropyl Ester: Potential Antiglaucoma Agents

Journal of medicinal chemistry, 1995-01, Vol.38 (2), p.289-304

1995

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(S)-UH-301 antagonizes (R)-8-OH-DPAT-indiiced cardiovascular effects in the rat

European journal of pharmacology, 1991-07, Vol.199 (3), p.367-370

1991

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Palladium catalyzed syntheses of phenyl-substittuted pgf 2α analogues: potential antigluaucoma agents

Bioorganic & medicinal chemistry letters, 1993, Vol.3 (2), p.241-244

1993

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Discovery of a Potent, Orally Available, and Isoform-Selective Retinoic Acid β2 Receptor Agonist

Pimavanserin, a selective serotonin (5-HT)2A-inverse agonist, enhances the efficacy and safety of risperidone, 2 mg/day, but does not enhance efficacy of haloperidol, 2 mg/day: Comparison with reference dose risperidone, 6 mg/day

Discovery of an Ectopic Activation Site on the M 1 Muscarinic Receptor

1 The Chemistry and Biochemistry of C-Nucleosides and C-Arylglycosides

Constitutively Active Mutants of the Histamine H 1 Receptor Suggest a Conserved Hydrophobic Asparagine-Cage That Constrains the Activation of Class A G Protein-Coupled Receptors

Atropisomeric Derivatives of 2‘,6‘-Disubstituted (R)-11-Phenylaporphine: Selective Serotonin 5-HT7 Receptor Antagonists

Pharmacology of polymorphic variants of the human 5-HT 1A receptor

Atropisomeric Derivatives of 2‘,6‘-Disubstituted ( R )-11-Phenylaporphine: Selective Serotonin 5-HT 7 Receptor Antagonists

Characterization of the Binding Site of the Histamine H 3 Receptor. 1. Various Approaches to the Synthesis of 2-(1 H -Imidazol-4-yl)cyclopropylamine and Histaminergic Activity of (1 R ,2 R )- and (1 S ,2 S )-2-(1 H -Imidazol-4-yl)- cyclopropylamine

Discovery of an Ectopic Activation Site on the M1Muscarinic Receptor

Intramolecular Transfer of CO from (.eta.6-arene)Cr(CO)3 Complexes in Stille-Type Palladium-Catalyzed Cross-Coupling Reactions

Animal Carotenoids. 32. Carotenoids of Mytilus edulis (Edible Mussel)

Interactions of ligands with active and inactive conformations of the dopamine D 2 receptor

Derivatives of 2-arylcyclopropylamine: Synthesis and interactions with 5-HT 1A receptors

trans-2-Aryl-N,N-dipropylcyclopropylamines: Synthesis and Interactions with 5-HT1A Receptors

Stereoselective palladium-catalyzed cyclopropanation of α,β-unsaturated carboxylic acids derivatized with oppolzer's sultam

3-Lithioquinuclidin-2-ene: A novel intermediate for the synthesis of muscarinic agonists and antagonists

Novel derivatives of 3-(dipropylamino)chroman. Interactions with 5-HT 1A and D 2A receptors

Palladium catalyzed syntheses of phenyl-substittuted pgf2α analogues: potential antigluaucoma agents

Ligand-controlled palladium-catalyzed intramolecular reactions of phenyl-substituted prostaglandin F2 α analogues

Derivatives of 2-arylcyclopropylamine: Synthesis and interactions with 5-HT1A receptors

Chemical genomics: massively parallel technologies for rapid lead identification and target validation

Derivatives of 17-Phenyl-18,19,20-trinorprostaglandin F2.alpha. Isopropyl Ester: Potential Antiglaucoma Agents

(S)-UH-301 antagonizes (R)-8-OH-DPAT-indiiced cardiovascular effects in the rat

Palladium catalyzed syntheses of phenyl-substittuted pgf 2α analogues: potential antigluaucoma agents

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