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1-{1-[4-[(N-acetyl-4-piperidinyl)oxy]-2-methoxybenzoyl]piperidin-4-yl}-4H-3,1-benzoxazin-2(1H)-one (L-371,257) : a new, orally bioavailable, non-peptide oxytocin antagonist

Journal of medicinal chemistry, 1995-11, Vol.38 (23), p.4634-4636

1995

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1-2-(2,2,2-Trifluoroethoxy)ethyl-1H-pyrazolo[4,3-d]pyrimidines as potent phosphodiesterase 5 (PDE5) inhibitors

Bioorganic & medicinal chemistry letters, 2010, Vol.20 (10), p.3125-3128

2010

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1,2,3,4-Tetrahydroisoquinolinyl sulfamic acids as phosphatase PTP1B inhibitors

Bioorganic & medicinal chemistry letters, 2006-03, Vol.16 (6), p.1574-1578

2006

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1,2,3-Triazolo[5,4-e]1,2,4-triazolo[1,5-c]pyrimidine derivatives: a new class of A2A adenosine receptor antagonists

Farmaco (Società chimica italiana : 1989), 1996-04, Vol.51 (4), p.297

1996

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1,2,4-Triazole d-ribose derivatives: Design, synthesis and antitumoral evaluation

European journal of medicinal chemistry, 2012, Vol.47 (1), p.104-110

2012

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1,2,4-Triazolo[3,4- a]pyridine as a novel, constrained template for fibrinogen receptor (GPIIb/IIIa) antagonists

Bioorganic & medicinal chemistry letters, 2001-10, Vol.11 (19), p.2619-2622

2001

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1,2,5,6-tetrahydropyridine oxime ethers incorporating electron withdrawing groups are potent and selective muscarinic agonists

Bioorganic & medicinal chemistry letters, 1994-02, Vol.4 (4), p.557-562

1994

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1-[2-[(5-Cyanopyridin-2-yl)amino]-ethylamino]acetyl-2-(S)-pyrrolidine-carbonitri le: A potent, selective, and orally bioavailable Dipeptidyl peptidase IV inhibitor with antihyperglycemic properties

Journal of medicinal chemistry, 2002, Vol.45 (12), p.2362-2365

2002

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1-(2,5-Dimethoxy-4-(trifluoromethyl)phenyl)-2-aminopropane: A Potent Serotonin 5-HT2A/2C Agonist

Journal of medicinal chemistry, 1994-12, Vol.37 (25), p.4346-4351

1994

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1,2,5-Thiadiazole Analogues of Aceclidine as Potent m1 Muscarinic Agonists

Journal of medicinal chemistry, 1998-01, Vol.41 (3), p.379-392

1998

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1,2-Diarylcyclopentenes as Selective Cyclooxygenase-2 Inhibitors and Orally Active Anti-inflammatory Agents

Journal of medicinal chemistry, 1995-10, Vol.38 (22), p.4570-4578

1995

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1,2-Dibenzamidobenzene Inhibitors of Human Factor Xa

Journal of medicinal chemistry, 2000-03, Vol.43 (5), p.859-872

2000

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1,2-dibromoethane and chloroform in the rainbow trout (Salmo Gairdneri): studies on the distribution of nonvolatile and irreversibly bound metabolites

Journal of toxicology and environmental health, 1989-01, Vol.26 (2), p.209-221

1989

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1-(2-Ethoxyethyl)-1H-pyrazolo[4,3-d]pyrimidines as potent phosphodiesterase 5 (PDE5) inhibitors

Bioorganic & medicinal chemistry letters, 2010-05, Vol.20 (10), p.3120-3124

2010

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1-[2-[(Heteroarylmethoxy)aryl]carbamoyl]indolines are selective and orally active 5-HT2C receptor inverse agonists

Bioorganic & medicinal chemistry letters, 2000-08, Vol.10 (16), p.1867-1870

2000

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1-[2-[(Heteroaryloxy)heteroaryl]carbamoyl]indolines : Novel and selective 5-HT2C receptor inverse agonists with potential as antidepressant/anxiolytic agents

Bioorganic & medicinal chemistry letters, 2000-08, Vol.10 (16), p.1863-1866

2000

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1-(2-Naphthyl)-1H-pyrazole-5-carboxylamides as potent factor xa inhibitors. Part 2: A survey of P4 motifs

Bioorganic & medicinal chemistry letters, 2004-03, Vol.14 (5), p.1221-1227

2004

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1-(2-Naphthyl)-1H-pyrazole-5-carboxylamides as potent factor xa inhibitors. Part 3: Design, synthesis and sar of orally bioavailable benzamidine-P4 inhibitors

Bioorganic & medicinal chemistry letters, 2004-03, Vol.14 (5), p.1229-1234

2004

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1,25-Dihydroxycalciferol and calcium therapy in osteoporosis with calcium malabsorption. Dose response relationship of calcium absorption and indices of bone turnover

Mineral and electrolyte metabolism, 1985, Vol.11 (1), p.35

1985

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1,25-Dihydroxyvitamin D3 induces splenocyte apoptosis and enhances BALB/c mice sensitivity to toxoplasmosis

The Journal of steroid biochemistry and molecular biology, 2005-07, Vol.96 (2), p.179-185

2005

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1,3,4-Trisubstituted pyrrolidine CCR5 receptor antagonists. Part 2: lead optimization affording selective, orally bioavailable compounds with potent Anti-HIV activity

Bioorganic & medicinal chemistry letters, 2001-10, Vol.11 (20), p.2741-2745

2001

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1-(3-Cyanobenzylpiperidin-4-yl)-5-methyl-4-phenyl-1,3-dihydroimidazol-2-one : A selective high-affinity antagonist for the human dopamine D4receptor with excellent selectivity over ion channels

Journal of medicinal chemistry, 1999, Vol.42 (14), p.2706-2715

1999

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1,3-dialkyltriazenes : reactie intermediates and DNA alkylation

Chemical research in toxicology, 1991, Vol.4 (3), p.334-340

1991

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1,3-Diaryl-4,5,6,7-tetrahydro-2H-isoindole Derivatives: A New Series of Potent and Selective COX-2 Inhibitors in Which a Sulfonyl Group Is Not a Structural Requisite

Journal of medicinal chemistry, 2000-11, Vol.43 (24), p.4582-4593

2000

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1,3-dioxane-4,6-dione-5-carboxamide-based inhibitors of human group IIa phospholipase A2 : X-ray structure of the complex and interfacial selection of inhibitors from a structural library

Bioorganic & medicinal chemistry letters, 1999-04, Vol.9 (8), p.1097-1102

1999

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