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CD4 depletion in SIV-infected macaques results in macrophage and microglia infection with rapid turnover of infected cells

PLoS pathogens, 2014-10, Vol.10 (10), p.e1004467-e1004467

2014

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CD163, a Marker of Perivascular Macrophages, Is Up-Regulated by Microglia in Simian Immunodeficiency Virus Encephalitis after Haptoglobin-Hemoglobin Complex Stimulation and Is Suggestive of Breakdown of the Blood-Brain Barrier

The American journal of pathology, 2008-03, Vol.172 (3), p.725-737

2008

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Dynamics of Cytokine/Chemokine Responses in Intestinal CD4+ and CD8+ T Cells during Acute Simian Immunodeficiency Virus Infection

Journal of Virology, 2013-11, Vol.87 (21), p.11916-11923

2013

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Focused examination of the intestinal epithelium reveals transcriptional signatures consistent with disturbances in enterocyte maturation and differentiation during the course of SIV infection

PloS one, 2013-04, Vol.8 (4), p.e60122-e60122

2013

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Focused examination of the intestinal lamina propria yields greater molecular insight into mechanisms underlying SIV induced immune dysfunction

PloS one, 2012-04, Vol.7 (4), p.e34561-e34561

2012

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Divergent Kinetics of Proliferating T Cell Subsets in Simian Immunodeficiency Virus (SIV) Infection: SIV Eliminates the “First Responder” CD4+ T Cells in Primary Infection

Journal of Virology, 2013-06, Vol.87 (12), p.7032-7038

2013

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T cell activation is insufficient to drive SIV disease progression

JCI insight, 2023-07, Vol.8 (14)

2023

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Simian Immunodeficiency Virus SIVagm.sab Infection of Caribbean African Green Monkeys: a New Model for the Study of SIV Pathogenesis in Natural Hosts

Journal of Virology, 2006-05, Vol.80 (10), p.4858-4867

2006

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Distinct expression patterns of CD69 in mucosal and systemic lymphoid tissues in primary SIV infection of rhesus macaques

PloS one, 2011-11, Vol.6 (11), p.e27207-e27207

2011

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Loss of a Tyrosine-Dependent Trafficking Motif in the Simian Immunodeficiency Virus Envelope Cytoplasmic Tail Spares Mucosal CD4 Cells but Does Not Prevent Disease Progression

Journal of Virology, 2013-02, Vol.87 (3), p.1528-1543

2013

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Molecular Epidemiology of Simian Immunodeficiency Virus SIVsm in U.S. Primate Centers Unravels the Origin of SIVmac and SIVstm

Journal of Virology, 2005-07, Vol.79 (14), p.8991-9005

2005

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Acute and Chronic T Cell Dynamics in the Livers of Simian Immunodeficiency Virus-Infected Macaques

Journal of Virology, 2012-05, Vol.86 (9), p.5244-5252

2012

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Classic AIDS in a Sooty Mangabey after an 18-Year Natural Infection

Journal of Virology, 2004-08, Vol.78 (16), p.8902-8908

2004

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A Single Amino Acid Mutation in the Envelope Cytoplasmic Tail Restores the Ability of an Attenuated Simian Immunodeficiency Virus Mutant To Deplete Mucosal CD4+ T Cells

Journal of Virology, 2013-12, Vol.87 (23), p.13048-13052

2013

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Dysregulated miR-34a-SIRT1-acetyl p65 axis is a potential mediator of immune activation in the colon during chronic simian immunodeficiency virus infection of rhesus macaques

The Journal of immunology (1950), 2015-01, Vol.194 (1), p.291-306

2015

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Persistent Simian Immunodeficiency Virus Infection Causes Ultimate Depletion of Follicular Th Cells in AIDS

The Journal of immunology (1950), 2015-11, Vol.195 (9), p.4351-4357

2015

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Recently Infiltrating MAC387+ Monocytes/ Macrophages: A Third Macrophage Population Involved in SIV and HIV Encephalitic Lesion Formation

The American journal of pathology, 2011-05, Vol.178 (5), p.2121-2135

2011

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In vivo proton magnetic resonance spectroscopy reveals region specific metabolic responses to SIV infection in the macaque brain

BMC neuroscience, 2009-06, Vol.10 (1), p.63-63, Article 63

2009

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Enteric Ganglionitis in Rhesus Macaques Infected with Simian Immunodeficiency Virus

Journal of Virology, 2007-06, Vol.81 (12), p.6265-6275

2007

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Cytokine/Chemokine responses in activated CD4+ and CD8+ T cells isolated from peripheral blood, bone marrow, and axillary lymph nodes during acute simian immunodeficiency virus infection

Journal of virology, 2014-08, Vol.88 (16), p.9442-9457

2014

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Lack of interleukin-10-mediated anti-inflammatory signals and upregulated interferon gamma production are linked to increased intestinal epithelial cell apoptosis in pathogenic simian immunodeficiency virus infection

Journal of virology, 2014-11, Vol.88 (22), p.13015-13028

2014

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Acquired immunodeficiency syndrome and the blood-brain barrier

Journal of neurovirology, 2009-01, Vol.15 (2), p.111-122

2009

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SIV antigen immunization induces transient antigen-specific T cell responses and selectively activates viral replication in draining lymph nodes in retroviral suppressed rhesus macaques

Retrovirology, 2011-07, Vol.8 (1), p.57-57, Article 57

2011

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Enhanced Expression of Proinflammatory Cytokines in the Central Nervous System Is Associated with Neuroinvasion by Simian Immunodeficiency Virus and the Development of Encephalitis

Journal of Virology, 2002-06, Vol.76 (11), p.5797-5802

2002

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Increased B7-H1 expression on dendritic cells correlates with programmed death 1 expression on T cells in simian immunodeficiency virus-infected macaques and may contribute to T cell dysfunction and disease progression

The Journal of immunology (1950), 2010-12, Vol.185 (12), p.7340-7348

2010

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CD4 depletion in SIV-infected macaques results in macrophage and microglia infection with rapid turnover of infected cells

CD163, a Marker of Perivascular Macrophages, Is Up-Regulated by Microglia in Simian Immunodeficiency Virus Encephalitis after Haptoglobin-Hemoglobin Complex Stimulation and Is Suggestive of Breakdown of the Blood-Brain Barrier

Dynamics of Cytokine/Chemokine Responses in Intestinal CD4+ and CD8+ T Cells during Acute Simian Immunodeficiency Virus Infection

Focused examination of the intestinal epithelium reveals transcriptional signatures consistent with disturbances in enterocyte maturation and differentiation during the course of SIV infection

Focused examination of the intestinal lamina propria yields greater molecular insight into mechanisms underlying SIV induced immune dysfunction

Divergent Kinetics of Proliferating T Cell Subsets in Simian Immunodeficiency Virus (SIV) Infection: SIV Eliminates the “First Responder” CD4+ T Cells in Primary Infection

T cell activation is insufficient to drive SIV disease progression

Simian Immunodeficiency Virus SIVagm.sab Infection of Caribbean African Green Monkeys: a New Model for the Study of SIV Pathogenesis in Natural Hosts

Distinct expression patterns of CD69 in mucosal and systemic lymphoid tissues in primary SIV infection of rhesus macaques

Loss of a Tyrosine-Dependent Trafficking Motif in the Simian Immunodeficiency Virus Envelope Cytoplasmic Tail Spares Mucosal CD4 Cells but Does Not Prevent Disease Progression

Molecular Epidemiology of Simian Immunodeficiency Virus SIVsm in U.S. Primate Centers Unravels the Origin of SIVmac and SIVstm

Acute and Chronic T Cell Dynamics in the Livers of Simian Immunodeficiency Virus-Infected Macaques

Classic AIDS in a Sooty Mangabey after an 18-Year Natural Infection

A Single Amino Acid Mutation in the Envelope Cytoplasmic Tail Restores the Ability of an Attenuated Simian Immunodeficiency Virus Mutant To Deplete Mucosal CD4+ T Cells

Dysregulated miR-34a-SIRT1-acetyl p65 axis is a potential mediator of immune activation in the colon during chronic simian immunodeficiency virus infection of rhesus macaques

Persistent Simian Immunodeficiency Virus Infection Causes Ultimate Depletion of Follicular Th Cells in AIDS

Recently Infiltrating MAC387+ Monocytes/ Macrophages: A Third Macrophage Population Involved in SIV and HIV Encephalitic Lesion Formation

In vivo proton magnetic resonance spectroscopy reveals region specific metabolic responses to SIV infection in the macaque brain

Enteric Ganglionitis in Rhesus Macaques Infected with Simian Immunodeficiency Virus

Cytokine/Chemokine responses in activated CD4+ and CD8+ T cells isolated from peripheral blood, bone marrow, and axillary lymph nodes during acute simian immunodeficiency virus infection

Lack of interleukin-10-mediated anti-inflammatory signals and upregulated interferon gamma production are linked to increased intestinal epithelial cell apoptosis in pathogenic simian immunodeficiency virus infection

Acquired immunodeficiency syndrome and the blood-brain barrier

SIV antigen immunization induces transient antigen-specific T cell responses and selectively activates viral replication in draining lymph nodes in retroviral suppressed rhesus macaques

Enhanced Expression of Proinflammatory Cytokines in the Central Nervous System Is Associated with Neuroinvasion by Simian Immunodeficiency Virus and the Development of Encephalitis

Increased B7-H1 expression on dendritic cells correlates with programmed death 1 expression on T cells in simian immunodeficiency virus-infected macaques and may contribute to T cell dysfunction and disease progression

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