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PI3Kγ inhibition suppresses microglia/TAM accumulation in glioblastoma microenvironment to promote exceptional temozolomide response

Proceedings of the National Academy of Sciences - PNAS, 2021-04, Vol.118 (16), p.1

2021

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Quinazoline based small molecule exerts potent tumour suppressive properties by inhibiting PI3K/Akt/FoxO3a signalling in experimental colon cancer

Cancer letters, 2015-04, Vol.359 (1), p.47-56

2015

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The PI3K AKT Pathway as a Target for Cancer Treatment

Annual review of medicine, 2016-01, Vol.67 (1), p.11-28

2016

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Management of adverse events associated with idelalisib treatment: expert panel opinion

Leukemia & lymphoma, 2015-10, Vol.56 (10), p.2779-2786

2015

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PI3K/Akt signaling in osteosarcoma

Clinica chimica acta, 2015-04, Vol.444, p.182-192

2015

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PI3K/Akt/mTOR signaling pathway and targeted therapy for glioblastoma

Oncotarget, 2016-05, Vol.7 (22), p.33440-33450

2016

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The Potential Value of the PI3K/Akt/mTOR Signaling Pathway for Assessing Prognosis in Cervical Cancer and as a Target for Therapy

Journal of cellular biochemistry, 2017-12, Vol.118 (12), p.4163-4169

2017

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Phosphatidylinositol 3‑Kinase (PI3K) and Phosphatidylinositol 3‑Kinase-Related Kinase (PIKK) Inhibitors: Importance of the Morpholine Ring

Journal of medicinal chemistry, 2015-01, Vol.58 (1), p.41-71

2015

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Effects of d‑Pinitol on Insulin Resistance through the PI3K/Akt Signaling Pathway in Type 2 Diabetes Mellitus Rats

Journal of agricultural and food chemistry, 2015-07, Vol.63 (26), p.6019-6026

2015

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Astaxanthin targets PI3K/Akt signaling pathway toward potential therapeutic applications

Food and chemical toxicology, 2020-11, Vol.145, p.111714-111714, Article 111714

2020

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Curcumin regulates proliferation, autophagy, and apoptosis in gastric cancer cells by affecting PI3K and P53 signaling

Journal of cellular physiology, 2018-06, Vol.233 (6), p.4634-4642

2018

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Targeting the PI3K/Akt signaling pathway in gastric carcinoma: A reality for personalized medicine?

World journal of gastroenterology : WJG, 2015-11, Vol.21 (43), p.12261-12273

2015

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Targeting the PI3K/AKT/mTOR pathway in estrogen receptor-positive breast cancer

Cancer treatment reviews, 2014-08, Vol.40 (7), p.862-871

Ciruelos Gil, Eva Maria

2014

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Rehmannioside A improves cognitive impairment and alleviates ferroptosis via activating PI3K/AKT/Nrf2 and SLC7A11/GPX4 signaling pathway after ischemia

Journal of ethnopharmacology, 2022-05, Vol.289, p.115021, Article 115021

2022

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Quercetin induces apoptosis and autophagy in primary effusion lymphoma cells by inhibiting PI3K/AKT/mTOR and STAT3 signaling pathways

The Journal of nutritional biochemistry, 2017-03, Vol.41, p.124-136

2017

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Both PI3K/Akt and ERK1/2 pathways participate in the protection by dexmedetomidine against transient focal cerebral ischemia/reperfusion injury in rats

Brain research, 2013-02, Vol.1494, p.1-8

2013

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Gymnemic Acid Ameliorates Hyperglycemia through PI3K/AKT- and AMPK-Mediated Signaling Pathways in Type 2 Diabetes Mellitus Rats

Journal of agricultural and food chemistry, 2019-11, Vol.67 (47), p.13051-13060

2019

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Identification of a role for the PI3K/AKT/mTOR signaling pathway in innate immune cells

PloS one, 2014-04, Vol.9 (4), p.e94496-e94496

2014

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Basal and Treatment-Induced Activation of AKT Mediates Resistance to Cell Death by AZD6244 (ARRY-142886) in Braf-Mutant Human Cutaneous Melanoma Cells

Cancer research (Chicago, Ill.), 2010-11, Vol.70 (21), p.8736-8747

2010

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A drug targeting only p110α can block phosphoinositide 3-kinase signalling and tumour growth in certain cell types

Biochemical journal, 2011-08, Vol.438 (1), p.53-62

2011

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Chrysin induces death of prostate cancer cells by inducing ROS and ER stress

Journal of cellular physiology, 2017-12, Vol.232 (12), p.3786-3797

2017

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Reciprocal Feedback Regulation of PI3K and Androgen Receptor Signaling in PTEN-Deficient Prostate Cancer

Cancer cell, 2011-05, Vol.19 (5), p.575-586

2011

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Cancer Network Disruption by a Single Molecule Inhibitor Targeting Both Histone Deacetylase Activity and Phosphatidylinositol 3-Kinase Signaling

Clinical cancer research, 2012-08, Vol.18 (15), p.4104-4113

2012

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Rottlerin induces autophagy and apoptosis in prostate cancer stem cells via PI3K/Akt/mTOR signaling pathway

Cancer letters, 2014-02, Vol.343 (2), p.179-189

2014

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PI3K Pathway Dependencies in Endometrioid Endometrial Cancer Cell Lines

Clinical cancer research, 2013-07, Vol.19 (13), p.3533-3544

2013

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PI3Kγ inhibition suppresses microglia/TAM accumulation in glioblastoma microenvironment to promote exceptional temozolomide response

Quinazoline based small molecule exerts potent tumour suppressive properties by inhibiting PI3K/Akt/FoxO3a signalling in experimental colon cancer

The PI3K AKT Pathway as a Target for Cancer Treatment

Management of adverse events associated with idelalisib treatment: expert panel opinion

PI3K/Akt signaling in osteosarcoma

PI3K/Akt/mTOR signaling pathway and targeted therapy for glioblastoma

The Potential Value of the PI3K/Akt/mTOR Signaling Pathway for Assessing Prognosis in Cervical Cancer and as a Target for Therapy

Phosphatidylinositol 3‑Kinase (PI3K) and Phosphatidylinositol 3‑Kinase-Related Kinase (PIKK) Inhibitors: Importance of the Morpholine Ring

Effects of d‑Pinitol on Insulin Resistance through the PI3K/Akt Signaling Pathway in Type 2 Diabetes Mellitus Rats

Astaxanthin targets PI3K/Akt signaling pathway toward potential therapeutic applications

Curcumin regulates proliferation, autophagy, and apoptosis in gastric cancer cells by affecting PI3K and P53 signaling

Targeting the PI3K/Akt signaling pathway in gastric carcinoma: A reality for personalized medicine?

Targeting the PI3K/AKT/mTOR pathway in estrogen receptor-positive breast cancer

Rehmannioside A improves cognitive impairment and alleviates ferroptosis via activating PI3K/AKT/Nrf2 and SLC7A11/GPX4 signaling pathway after ischemia

Quercetin induces apoptosis and autophagy in primary effusion lymphoma cells by inhibiting PI3K/AKT/mTOR and STAT3 signaling pathways

Both PI3K/Akt and ERK1/2 pathways participate in the protection by dexmedetomidine against transient focal cerebral ischemia/reperfusion injury in rats

Gymnemic Acid Ameliorates Hyperglycemia through PI3K/AKT- and AMPK-Mediated Signaling Pathways in Type 2 Diabetes Mellitus Rats

Identification of a role for the PI3K/AKT/mTOR signaling pathway in innate immune cells

Basal and Treatment-Induced Activation of AKT Mediates Resistance to Cell Death by AZD6244 (ARRY-142886) in Braf-Mutant Human Cutaneous Melanoma Cells

A drug targeting only p110α can block phosphoinositide 3-kinase signalling and tumour growth in certain cell types

Chrysin induces death of prostate cancer cells by inducing ROS and ER stress

Reciprocal Feedback Regulation of PI3K and Androgen Receptor Signaling in PTEN-Deficient Prostate Cancer

Cancer Network Disruption by a Single Molecule Inhibitor Targeting Both Histone Deacetylase Activity and Phosphatidylinositol 3-Kinase Signaling

Rottlerin induces autophagy and apoptosis in prostate cancer stem cells via PI3K/Akt/mTOR signaling pathway

PI3K Pathway Dependencies in Endometrioid Endometrial Cancer Cell Lines

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