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Extracellular M. tuberculosis DNA Targets Bacteria for Autophagy by Activating the Host DNA-Sensing Pathway

Cell, 2012-08, Vol.150 (4), p.803-815

2012

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The Cytosolic Sensor cGAS Detects Mycobacterium tuberculosis DNA to Induce Type I Interferons and Activate Autophagy

Cell host & microbe, 2015-06, Vol.17 (6), p.811-819

2015

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Mycobacterium Tuberculosis Activates the DNA-Dependent Cytosolic Surveillance Pathway within Macrophages

Cell host & microbe, 2012-05, Vol.11 (5), p.469-480

2012

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The ubiquitin ligase parkin mediates resistance to intracellular pathogens

Nature (London), 2013-09, Vol.501 (7468), p.512-516

2013

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Comprehensive functional analysis of Mycobacterium tuberculosis toxin-antitoxin systems: implications for pathogenesis, stress responses, and evolution

PLoS genetics, 2009-12, Vol.5 (12), p.e1000767-e1000767

2009

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Interferon-independent STING signaling promotes resistance to HSV-1 in vivo

Nature communications, 2020-07, Vol.11 (1), p.3382-3382, Article 3382

2020

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Deficiency in Galectin-3, -8, and -9 impairs immunity to chronic Mycobacterium tuberculosis infection but not acute infection with multiple intracellular pathogens

PLoS pathogens, 2023-06, Vol.19 (6), p.e1011088-e1011088

2023

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Substrates Control Multimerization and Activation of the Multi-Domain ATPase Motor of Type VII Secretion

Cell, 2015-04, Vol.161 (3), p.501-512

2015

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Salmonella Require the Fatty Acid Regulator PPARδ for the Establishment of a Metabolic Environment Essential for Long-Term Persistence

Cell host & microbe, 2013-08, Vol.14 (2), p.171-182

2013

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Global Mapping of the Inc-Human Interactome Reveals that Retromer Restricts Chlamydia Infection

Cell host & microbe, 2015-07, Vol.18 (1), p.109-121

2015

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An Mtb-Human Protein-Protein Interaction Map Identifies a Switch between Host Antiviral and Antibacterial Responses

Molecular cell, 2018-08, Vol.71 (4), p.637-648.e5

2018

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Secreted transcription factor controls Mycobacterium tuberculosis virulence

Nature, 2008-08, Vol.454 (7205), p.717-721

2008

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Genetic Screen for Mycobacterium tuberculosis Mutants Defective for Phagosome Maturation Arrest Identifies Components of the ESX-1 Secretion System

Infection and Immunity, 2007-06, Vol.75 (6), p.2668-2678

2007

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IFN-γ-independent control of M. tuberculosis requires CD4 T cell-derived GM-CSF and activation of HIF-1α

PLoS pathogens, 2022-07, Vol.18 (7), p.e1010721-e1010721

2022

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Systematic genetic nomenclature for type VII secretion systems

PLoS pathogens, 2009-10, Vol.5 (10), p.e1000507-e1000507

2009

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Distinct TLR- and NLR-mediated transcriptional responses to an intracellular pathogen

PLoS pathogens, 2008-01, Vol.4 (1), p.e6-e6

2008

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Dynamic post-translational modification profiling of Mycobacterium tuberculosis -infected primary macrophages

eLife, 2020-01, Vol.9

2020

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Interaction between polyketide synthase and transporter suggests coupled synthesis and export of virulence lipid in M. tuberculosis

PLoS pathogens, 2005-09, Vol.1 (1), p.e2

2005

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Ceragenins and Antimicrobial Peptides Kill Bacteria through Distinct Mechanisms

mBio, 2022-02, Vol.13 (1), p.e0272621-e0272621

2022

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A mycobacterium ESX-1-secreted virulence factor with unique requirements for export

PLoS pathogens, 2007-08, Vol.3 (8), p.e105-e105

2007

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Cas9 + conditionally-immortalized macrophages as a tool for bacterial pathogenesis and beyond

eLife, 2019-06, Vol.8

2019

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A Protein Secretion Pathway Critical for Mycobacterium tuberculosis Virulence Is Conserved and Functional in Mycobacterium smegmatis

Journal of Bacteriology, 2005-02, Vol.187 (4), p.1238-1245

2005

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Role of KatG catalase‐peroxidase in mycobacterial pathogenesis: countering the phagocyte oxidative burst

Molecular microbiology, 2004-06, Vol.52 (5), p.1291-1302

2004

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A non‐RD1 gene cluster is required for Snm secretion in Mycobacterium tuberculosis

Molecular microbiology, 2005-09, Vol.57 (6), p.1653-1663

2005

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Architectures of Lipid Transport Systems for the Bacterial Outer Membrane

Cell, 2017-04, Vol.169 (2), p.273-285.e17

2017

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Extracellular M. tuberculosis DNA Targets Bacteria for Autophagy by Activating the Host DNA-Sensing Pathway

The Cytosolic Sensor cGAS Detects Mycobacterium tuberculosis DNA to Induce Type I Interferons and Activate Autophagy

Mycobacterium Tuberculosis Activates the DNA-Dependent Cytosolic Surveillance Pathway within Macrophages

The ubiquitin ligase parkin mediates resistance to intracellular pathogens

Comprehensive functional analysis of Mycobacterium tuberculosis toxin-antitoxin systems: implications for pathogenesis, stress responses, and evolution

Interferon-independent STING signaling promotes resistance to HSV-1 in vivo

Deficiency in Galectin-3, -8, and -9 impairs immunity to chronic Mycobacterium tuberculosis infection but not acute infection with multiple intracellular pathogens

Substrates Control Multimerization and Activation of the Multi-Domain ATPase Motor of Type VII Secretion

Salmonella Require the Fatty Acid Regulator PPARδ for the Establishment of a Metabolic Environment Essential for Long-Term Persistence

Global Mapping of the Inc-Human Interactome Reveals that Retromer Restricts Chlamydia Infection

An Mtb-Human Protein-Protein Interaction Map Identifies a Switch between Host Antiviral and Antibacterial Responses

Secreted transcription factor controls Mycobacterium tuberculosis virulence

Genetic Screen for Mycobacterium tuberculosis Mutants Defective for Phagosome Maturation Arrest Identifies Components of the ESX-1 Secretion System

IFN-γ-independent control of M. tuberculosis requires CD4 T cell-derived GM-CSF and activation of HIF-1α

Systematic genetic nomenclature for type VII secretion systems

Distinct TLR- and NLR-mediated transcriptional responses to an intracellular pathogen

Dynamic post-translational modification profiling of Mycobacterium tuberculosis -infected primary macrophages

Interaction between polyketide synthase and transporter suggests coupled synthesis and export of virulence lipid in M. tuberculosis

Ceragenins and Antimicrobial Peptides Kill Bacteria through Distinct Mechanisms

A mycobacterium ESX-1-secreted virulence factor with unique requirements for export

Cas9 + conditionally-immortalized macrophages as a tool for bacterial pathogenesis and beyond

A Protein Secretion Pathway Critical for Mycobacterium tuberculosis Virulence Is Conserved and Functional in Mycobacterium smegmatis

Role of KatG catalase‐peroxidase in mycobacterial pathogenesis: countering the phagocyte oxidative burst

A non‐RD1 gene cluster is required for Snm secretion in Mycobacterium tuberculosis

Architectures of Lipid Transport Systems for the Bacterial Outer Membrane

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