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Backbone modification of a polypeptide drug alters duration of action in vivo

Nature biotechnology, 2014-07, Vol.32 (7), p.653-655

2014

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Characterization of signal bias at the GLP-1 receptor induced by backbone modification of GLP-1

Biochemical pharmacology, 2017-07, Vol.136, p.99-108

2017

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Local rigidification and possible coacervation of the Escherichia coli DNA by cationic nylon-3 polymers

Biophysical journal, 2021-12, Vol.120 (23), p.5243-5254

2021

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Targeting protein-protein interactions: Lessons from p53/MDM2

Biopolymers, 2007, Vol.88 (5), p.657-686

2007

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Polymer Chain Length Effects on Fibroblast Attachment on Nylon-3-Modified Surfaces

Biomacromolecules, 2012-04, Vol.13 (4), p.1100-1105

2012

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Two interdependent mechanisms of antimicrobial activity allow for efficient killing in nylon-3-based polymeric mimics of innate immunity peptides

Biochimica et biophysica acta, 2014-09, Vol.1838 (9), p.2269-2279

2014

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Targeting recognition surfaces on natural proteins with peptidic foldamers

Current opinion in structural biology, 2016-08, Vol.39, p.96-105

2016

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Comparisons of β‐Hairpin Propensity Among Peptides with Homochiral or Heterochiral Strands

Chembiochem : a European journal of chemical biology, 2021-09, Vol.22 (18), p.2772-2776

2021

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PTH receptor-1 signalling-mechanistic insights and therapeutic prospects

Nature reviews. Endocrinology, 2015-12, Vol.11 (12), p.712

2015

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Effects of Replacing a Central Glycine Residue in GLP‐1 on Receptor Affinity and Signaling Profile

Chembiochem : a European journal of chemical biology, 2023-11, Vol.24 (21), p.e202300504-e202300504

2023

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Interactions of SARS-CoV-2 and MERS-CoV fusion peptides measured using single-molecule force methods

Biophysical journal, 2023-02, Vol.122 (4), p.646-660

2023

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Glycotripod Amphiphiles for Solubilization and Stabilization of a Membrane-Protein Superassembly: Importance of Branching in the Hydrophilic Portion

Chembiochem : a European journal of chemical biology, 2008-07, Vol.9 (11), p.1706-1709

2008

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Structural and functional diversity among agonist-bound states of the GLP-1 receptor

Nature chemical biology, 2022-03, Vol.18 (3), p.256

2022

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Iterative Nonproteinogenic Residue Incorporation Yields α/β‐Peptides with a Helix–Loop–Helix Tertiary Structure and High Affinity for VEGF

Chembiochem : a European journal of chemical biology, 2017-02, Vol.18 (3), p.291-299

2017

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Artificial Chaperone-Assisted Refolding of Denatured-Reduced Lysozyme: Modulation of the Competition between Renaturation and Aggregation

Biochemistry (Easton), 1996-12, Vol.35 (49), p.15760-15771

1996

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Single-Cell, Time-Resolved Antimicrobial Effects of a Highly Cationic, Random Nylon‑3 Copolymer on Live Escherichia coli

ACS chemical biology, 2016-01, Vol.11 (1), p.113-120

2016

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Inhibition of Herpes Simplex Virus Type 1 Infection by Cationic β-Peptides

Antimicrobial Agents and Chemotherapy, 2008-06, Vol.52 (6), p.2120-2129

2008

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Peptide-Like Nylon-3 Polymers with Activity against Phylogenetically Diverse, Intrinsically Drug-Resistant Pathogenic Fungi

mSphere, 2018-05, Vol.3 (3)

2018

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Spatial bias in cAMP generation determines biological responses to PTH type 1 receptor activation

Science signaling, 2021-10, Vol.14 (703), p.eabc5944

2021

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Impact of Substitution Registry on the Receptor‐Activation Profiles of Backbone‐Modified Glucagon‐like Peptide‐1 Analogues

Chembiochem : a European journal of chemical biology, 2019-11, Vol.20 (22), p.2834-2840

2019

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Maltose-neopentyl glycol (MNG) amphiphiles for solubilization, stabilization and crystallization of membrane proteins

Nature methods, 2010-12, Vol.7 (12), p.1003

2010

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α-Helix Mimicry with α/β-Peptides

Methods in Enzymology, 2013, Vol.523, p.407-429

2013

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Kinetic and Thermodynamic Insights into Agonist Interactions with the Parathyroid Hormone Receptor‑1 from a New NanoBRET Assay

ACS chemical biology, 2022-11, Vol.17 (11), p.3148-3158

2022

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Stable Picodisc Assemblies from Saposin Proteins and Branched Detergents

Biochemistry (Easton), 2021-04, Vol.60 (14), p.1108-1119

2021

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Backbone modification of a polypeptide drug alters duration of action in vivo

Characterization of signal bias at the GLP-1 receptor induced by backbone modification of GLP-1

Local rigidification and possible coacervation of the Escherichia coli DNA by cationic nylon-3 polymers

Targeting protein-protein interactions: Lessons from p53/MDM2

Polymer Chain Length Effects on Fibroblast Attachment on Nylon-3-Modified Surfaces

Two interdependent mechanisms of antimicrobial activity allow for efficient killing in nylon-3-based polymeric mimics of innate immunity peptides

Targeting recognition surfaces on natural proteins with peptidic foldamers

Comparisons of β‐Hairpin Propensity Among Peptides with Homochiral or Heterochiral Strands

PTH receptor-1 signalling-mechanistic insights and therapeutic prospects

Effects of Replacing a Central Glycine Residue in GLP‐1 on Receptor Affinity and Signaling Profile

Interactions of SARS-CoV-2 and MERS-CoV fusion peptides measured using single-molecule force methods

Glycotripod Amphiphiles for Solubilization and Stabilization of a Membrane-Protein Superassembly: Importance of Branching in the Hydrophilic Portion

Structural and functional diversity among agonist-bound states of the GLP-1 receptor

Iterative Nonproteinogenic Residue Incorporation Yields α/β‐Peptides with a Helix–Loop–Helix Tertiary Structure and High Affinity for VEGF

Artificial Chaperone-Assisted Refolding of Denatured-Reduced Lysozyme: Modulation of the Competition between Renaturation and Aggregation

Single-Cell, Time-Resolved Antimicrobial Effects of a Highly Cationic, Random Nylon‑3 Copolymer on Live Escherichia coli

Inhibition of Herpes Simplex Virus Type 1 Infection by Cationic β-Peptides

Inhibition of Coronavirus Entry In Vitro and Ex Vivo by a Lipid-Conjugated Peptide Derived from the SARS-CoV-2 Spike Glycoprotein HRC Domain

Peptide-Like Nylon-3 Polymers with Activity against Phylogenetically Diverse, Intrinsically Drug-Resistant Pathogenic Fungi

Spatial bias in cAMP generation determines biological responses to PTH type 1 receptor activation

Impact of Substitution Registry on the Receptor‐Activation Profiles of Backbone‐Modified Glucagon‐like Peptide‐1 Analogues

Maltose-neopentyl glycol (MNG) amphiphiles for solubilization, stabilization and crystallization of membrane proteins

α-Helix Mimicry with α/β-Peptides

Kinetic and Thermodynamic Insights into Agonist Interactions with the Parathyroid Hormone Receptor‑1 from a New NanoBRET Assay

Stable Picodisc Assemblies from Saposin Proteins and Branched Detergents

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