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MC1R Is a Potent Regulator of PTEN after UV Exposure in Melanocytes

Molecular cell, 2013-08, Vol.51 (4), p.409-422

2013

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Non-genomic loss of PTEN function in cancer: not in my genes

Trends in pharmacological sciences (Regular ed.), 2011-03, Vol.32 (3), p.131-140

2011

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The redox regulation of PI 3-kinase-dependent signaling

Antioxidants & redox signaling, 2006-09, Vol.8 (9-10), p.1765-1774

Leslie, Nick R

2006

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GSK3 and its interactions with the PI3K/AKT/mTOR signalling network

Advances in biological regulation, 2017-08, Vol.65, p.5-15

2017

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PTEN function: how normal cells control it and tumour cells lose it

Biochemical journal, 2004-08, Vol.382 (Pt 1), p.1-11

2004

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Proteomic and yeast 2-hybrid screens to identify PTEN binding partners

Advances in biological regulation, 2024-01, Vol.91, p.100989, Article 100989

2024

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The PTEN protein: cellular localization and post-translational regulation

Biochemical Society transactions, 2016-02, Vol.44 (1), p.273-278

2016

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PTEN posttranslational inactivation and hyperactivation of the PI3K/Akt pathway sustain primary T cell leukemia viability

The Journal of clinical investigation, 2008-11, Vol.118 (11), p.3762-3774

2008

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PTEN: an intercellular peacekeeper?

Science signaling, 2012-11, Vol.5 (250), p.pe50

Leslie, Nick R

2012

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PTEN protein phosphatase activity correlates with control of gene expression and invasion, a tumor-suppressing phenotype, but not with AKT activity

Science signaling, 2012-02, Vol.5 (213), p.ra18

2012

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Cross Talk between the Akt and p38α Pathways in Macrophages Downstream of Toll-Like Receptor Signaling

Molecular and Cellular Biology, 2013-11, Vol.33 (21), p.4152-4165

2013

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Redox regulation of PI 3-kinase signalling via inactivation of PTEN

The EMBO journal, 2003-10, Vol.22 (20), p.5501-5510

2003

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Use of Akt Inhibitor and a Drug-resistant Mutant Validates a Critical Role for Protein Kinase B/Akt in the Insulin-dependent Regulation of Glucose and System A Amino Acid Uptake

The Journal of biological chemistry, 2008-10, Vol.283 (41), p.27653-27667

2008

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Hypomorphic Mutation of PDK1 Suppresses Tumorigenesis in PTEN+/− Mice

Current biology, 2005-10, Vol.15 (20), p.1839-1846

2005

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Ubiquitination of PTEN (Phosphatase and Tensin Homolog) Inhibits Phosphatase Activity and Is Enhanced by Membrane Targeting and Hyperosmotic Stress

The Journal of biological chemistry, 2010-04, Vol.285 (17), p.12620-12628

2010

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PTEN: The down side of PI 3-kinase signalling

Cellular Signalling, 2002-04, Vol.14 (4), p.285-295

2002

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Localization of agonist-sensitive PtdIns(3,4,5)P₃ reveals a nuclear pool that is insensitive to PTEN expression

Journal of cell science, 2006-12, Vol.119 (24), p.5160-5168

2006

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P-REX2a driving tumorigenesis by PTEN inhibition

Science signaling, 2009-10, Vol.2 (94), p.pe68

Leslie, Nick R

2009

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Differential redox regulation within the PTP superfamily

Cellular signalling, 2007-07, Vol.19 (7), p.1521-1530

2007

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The tumour-suppressor function of PTEN requires an N-terminal lipid-binding motif

Biochemical journal, 2004-04, Vol.379 (Pt 2), p.301-307

2004

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A novel leptin signalling pathway via PTEN inhibition in hypothalamic cell lines and pancreatic β-cells

The EMBO journal, 2006-06, Vol.25 (11), p.2377-2387

2006

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Distinct inactivation of PI3K signalling by PTEN and 5-phosphatases

Advances in biological regulation, 2012-01, Vol.52 (1), p.205-213

2012

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Phosphoinositide-Regulated Kinases and Phosphoinositide Phosphatases

Chemical reviews, 2001-08, Vol.101 (8), p.2365-2380

2001

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Detection of novel intracellular agonist responsive pools of phosphatidylinositol 3,4-bisphosphate using the TAPP1 pleckstrin homology domain in immunoelectron microscopy

Biochemical journal, 2004-02, Vol.377 (Pt 3), p.653-663

2004

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Mechanism of Activation of PKB/Akt by the Protein Phosphatase Inhibitor Calyculin A

Cell biochemistry and biophysics, 2010-12, Vol.58 (3), p.147-156

2010

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MC1R Is a Potent Regulator of PTEN after UV Exposure in Melanocytes

Non-genomic loss of PTEN function in cancer: not in my genes

The redox regulation of PI 3-kinase-dependent signaling

GSK3 and its interactions with the PI3K/AKT/mTOR signalling network

PTEN function: how normal cells control it and tumour cells lose it

Proteomic and yeast 2-hybrid screens to identify PTEN binding partners

The PTEN protein: cellular localization and post-translational regulation

PTEN posttranslational inactivation and hyperactivation of the PI3K/Akt pathway sustain primary T cell leukemia viability

PTEN: an intercellular peacekeeper?

PTEN protein phosphatase activity correlates with control of gene expression and invasion, a tumor-suppressing phenotype, but not with AKT activity

Cross Talk between the Akt and p38α Pathways in Macrophages Downstream of Toll-Like Receptor Signaling

Redox regulation of PI 3-kinase signalling via inactivation of PTEN

Use of Akt Inhibitor and a Drug-resistant Mutant Validates a Critical Role for Protein Kinase B/Akt in the Insulin-dependent Regulation of Glucose and System A Amino Acid Uptake

Hypomorphic Mutation of PDK1 Suppresses Tumorigenesis in PTEN+/− Mice

Ubiquitination of PTEN (Phosphatase and Tensin Homolog) Inhibits Phosphatase Activity and Is Enhanced by Membrane Targeting and Hyperosmotic Stress

PTEN: The down side of PI 3-kinase signalling

Localization of agonist-sensitive PtdIns(3,4,5)P₃ reveals a nuclear pool that is insensitive to PTEN expression

P-REX2a driving tumorigenesis by PTEN inhibition

Differential redox regulation within the PTP superfamily

The tumour-suppressor function of PTEN requires an N-terminal lipid-binding motif

A novel leptin signalling pathway via PTEN inhibition in hypothalamic cell lines and pancreatic β-cells

Distinct inactivation of PI3K signalling by PTEN and 5-phosphatases

Phosphoinositide-Regulated Kinases and Phosphoinositide Phosphatases

Detection of novel intracellular agonist responsive pools of phosphatidylinositol 3,4-bisphosphate using the TAPP1 pleckstrin homology domain in immunoelectron microscopy

Mechanism of Activation of PKB/Akt by the Protein Phosphatase Inhibitor Calyculin A

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