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CD8+ T cells and fatty acids orchestrate tumor ferroptosis and immunity via ACSL4

Cancer cell, 2022-04, Vol.40 (4), p.365-378.e6

2022

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miRNA-17-92 protects endothelial cells from erastin-induced ferroptosis through targeting the A20-ACSL4 axis

Biochemical and biophysical research communications, 2019-07, Vol.515 (3), p.448-454

2019

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ACSL4 exacerbates ischemic stroke by promoting ferroptosis-induced brain injury and neuroinflammation

Brain, behavior, and immunity, 2021-03, Vol.93, p.312-321

2021

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Baicalein ameliorates cerebral ischemia-reperfusion injury by inhibiting ferroptosis via regulating GPX4/ACSL4/ACSL3 axis

Chemico-biological interactions, 2022-10, Vol.366, p.110137-110137, Article 110137

2022

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Selenium Utilization by GPX4 Is Required to Prevent Hydroperoxide-Induced Ferroptosis

Cell, 2018-01, Vol.172 (3), p.409-422.e21

2018

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ACSL4 is overexpressed in psoriasis and enhances inflammatory responses by activating ferroptosis

Biochemical and biophysical research communications, 2022-10, Vol.623, p.1-8

2022

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Acyl-CoA synthetase-4 is implicated in drug resistance in breast cancer cell lines involving the regulation of energy-dependent transporter expression

Biochemical pharmacology, 2019-01, Vol.159, p.52-63

2019

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ACSL4 promotes malignant progression of Hepatocellular carcinoma by targeting PAK2 transcription

Biochemical pharmacology, 2024-06, Vol.224, p.116206, Article 116206

2024

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Ferroptosis involves in renal tubular cell death in diabetic nephropathy

European journal of pharmacology, 2020-12, Vol.888, p.173574-173574, Article 173574

2020

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Context-dependent regulation of ferroptosis sensitivity

Cell chemical biology, 2022-09, Vol.29 (9), p.1409-1418.e6

2022

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ACSL4 promotes ferroptosis and M1 macrophage polarization to regulate the tumorigenesis of nasopharyngeal carcinoma

International immunopharmacology, 2023-09, Vol.122, p.110629-110629, Article 110629

2023

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Proteomic analysis reveals that ACSL4 activation during reflux esophagitis contributes to ferroptosis-mediated esophageal mucosal damage

European journal of pharmacology, 2022-09, Vol.931, p.175175-175175, Article 175175

2022

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Acyl-CoA synthetase-4 mediates radioresistance of breast cancer cells by regulating FOXM1

Biochemical pharmacology, 2021-10, Vol.192, p.114718-114718, Article 114718

2021

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ACSL4 reprograms fatty acid metabolism in hepatocellular carcinoma via c-Myc/SREBP1 pathway

Cancer letters, 2021-04, Vol.502, p.154-165

2021

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MitoQ protects against carbon tetrachloride-induced hepatocyte ferroptosis and acute liver injury by suppressing mtROS-mediated ACSL4 upregulation

Toxicology and applied pharmacology, 2024-05, Vol.486, p.116914-116914, Article 116914

2024

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Ring Finger Protein 146-mediated Long-chain Fatty-acid-Coenzyme a Ligase 4 Ubiquitination Regulates Ferroptosis-induced Neuronal Damage in Ischemic Stroke

Neuroscience, 2023-10, Vol.529, p.148-161

2023

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FUNDC1 insufficiency sensitizes high fat diet intake-induced cardiac remodeling and contractile anomaly through ACSL4-mediated ferroptosis

Metabolism, clinical and experimental, 2021-09, Vol.122, p.154840-154840, Article 154840

2021

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Role of acyl-CoA synthetase ACSL4 in arachidonic acid metabolism

Prostaglandins & other lipid mediators, 2019-10, Vol.144, p.106363-106363, Article 106363

2019

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Liquidambaric acid inhibits the proliferation of hepatocellular carcinoma cells by targeting PPARα-RXRα to down-regulate fatty acid metabolism

Toxicology and applied pharmacology, 2024-09, Vol.490, p.117042, Article 117042

2024

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Breast cancer molecular subtypes: from TNBC to QNBC

American journal of cancer research, 2016-01, Vol.6 (9), p.1864-1872

2016

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Specific cellular microenvironments for spatiotemporal regulation of StAR and steroid synthesis

Journal of endocrinology, 2024-05, Vol.261 (2)

2024

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Necroptosis and ferroptosis are alternative cell death pathways that operate in acute kidney failure

Cellular and molecular life sciences : CMLS, 2017-10, Vol.74 (19), p.3631-3645

2017

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Kidney tubular epithelial cell ferroptosis links glomerular injury to tubulointerstitial pathology in lupus nephritis

Clinical immunology (Orlando, Fla.), 2023-03, Vol.248, p.109213-109213, Article 109213

2023

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ACSL3 and ACSL4, Distinct Roles in Ferroptosis and Cancers

Cancers, 2022-11, Vol.14 (23), p.5896

2022

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ACSL4 accelerates osteosarcoma progression via modulating TGF-β/Smad2 signaling pathway

Molecular and cellular biochemistry, 2024-04

2024

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CD8+ T cells and fatty acids orchestrate tumor ferroptosis and immunity via ACSL4

miRNA-17-92 protects endothelial cells from erastin-induced ferroptosis through targeting the A20-ACSL4 axis

ACSL4 exacerbates ischemic stroke by promoting ferroptosis-induced brain injury and neuroinflammation

Baicalein ameliorates cerebral ischemia-reperfusion injury by inhibiting ferroptosis via regulating GPX4/ACSL4/ACSL3 axis

Selenium Utilization by GPX4 Is Required to Prevent Hydroperoxide-Induced Ferroptosis

ACSL4 is overexpressed in psoriasis and enhances inflammatory responses by activating ferroptosis

Acyl-CoA synthetase-4 is implicated in drug resistance in breast cancer cell lines involving the regulation of energy-dependent transporter expression

ACSL4 promotes malignant progression of Hepatocellular carcinoma by targeting PAK2 transcription

Ferroptosis involves in renal tubular cell death in diabetic nephropathy

Context-dependent regulation of ferroptosis sensitivity

ACSL4 promotes ferroptosis and M1 macrophage polarization to regulate the tumorigenesis of nasopharyngeal carcinoma

Proteomic analysis reveals that ACSL4 activation during reflux esophagitis contributes to ferroptosis-mediated esophageal mucosal damage

Acyl-CoA synthetase-4 mediates radioresistance of breast cancer cells by regulating FOXM1

ACSL4 reprograms fatty acid metabolism in hepatocellular carcinoma via c-Myc/SREBP1 pathway

MitoQ protects against carbon tetrachloride-induced hepatocyte ferroptosis and acute liver injury by suppressing mtROS-mediated ACSL4 upregulation

Ring Finger Protein 146-mediated Long-chain Fatty-acid-Coenzyme a Ligase 4 Ubiquitination Regulates Ferroptosis-induced Neuronal Damage in Ischemic Stroke

FUNDC1 insufficiency sensitizes high fat diet intake-induced cardiac remodeling and contractile anomaly through ACSL4-mediated ferroptosis

Role of acyl-CoA synthetase ACSL4 in arachidonic acid metabolism

Liquidambaric acid inhibits the proliferation of hepatocellular carcinoma cells by targeting PPARα-RXRα to down-regulate fatty acid metabolism

Breast cancer molecular subtypes: from TNBC to QNBC

Specific cellular microenvironments for spatiotemporal regulation of StAR and steroid synthesis

Necroptosis and ferroptosis are alternative cell death pathways that operate in acute kidney failure

Kidney tubular epithelial cell ferroptosis links glomerular injury to tubulointerstitial pathology in lupus nephritis

ACSL3 and ACSL4, Distinct Roles in Ferroptosis and Cancers

ACSL4 accelerates osteosarcoma progression via modulating TGF-β/Smad2 signaling pathway

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