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Rational design of small molecule fluorescent probes for biological applications

Organic & biomolecular chemistry, 2020-08, Vol.18 (3), p.5747-5763

2020

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New strategies for fluorescently labeling proteins in the study of amyloids

Current opinion in chemical biology, 2021-10, Vol.64, p.57-66

2021

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Biosynthesis and Chemical Applications of Thioamides

ACS chemical biology, 2019-02, Vol.14 (2), p.142-163

2019

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Scalable thioarylation of unprotected peptides and biomolecules under Ni/photoredox catalysis

Chemical science (Cambridge), 2018, Vol.9 (2), p.336-344

2018

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Molecular basis for N-terminal acetylation by the heterodimeric NatA complex

Nature structural & molecular biology, 2013-09, Vol.20 (9), p.1098-1105

2013

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Thioamide Substitution Selectively Modulates Proteolysis and Receptor Activity of Therapeutic Peptide Hormones

Journal of the American Chemical Society, 2017-11, Vol.139 (46), p.16688-16695

2017

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Post-translational modifications of soluble α-synuclein regulate the amplification of pathological α-synuclein

Nature neuroscience, 2023-02, Vol.26 (2), p.213-225

2023

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Insights into genome recoding from the mechanism of a classic +1-frameshifting tRNA

Nature communications, 2021-01, Vol.12 (1), p.328-328, Article 328

2021

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Molecular basis for N-terminal alpha-synuclein acetylation by human NatB

eLife, 2020-09, Vol.9

2020

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Rosetta custom score functions accurately predict ΔΔG of mutations at protein-protein interfaces using machine learning

Chemical communications (Cambridge, England), 2020-06, Vol.56 (50), p.6774-6777

2020

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Optimization of Second Window Indocyanine Green for Intraoperative Near-Infrared Imaging of Thoracic Malignancy

Journal of the American College of Surgeons, 2019-02, Vol.228 (2), p.188-197

2019

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Multiply labeling proteins for studies of folding and stability

Current opinion in chemical biology, 2015-10, Vol.28, p.123-130

2015

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Rational design of thioamide peptides as selective inhibitors of cysteine protease cathepsin L

Chemical science (Cambridge), 2021-08, Vol.12 (32), p.1825-1835

2021

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Efficient synthesis and in vivo incorporation of acridon-2-ylalanine, a fluorescent amino acid for lifetime and Förster resonance energy transfer/luminescence resonance energy transfer studies

Journal of the American Chemical Society, 2013-12, Vol.135 (50), p.18806-18814

2013

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An improved fluorescent noncanonical amino acid for measuring conformational distributions using time-resolved transition metal ion FRET

eLife, 2021-10, Vol.10

2021

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Generating Efficient Methanomethylophilus alvus Pyrrolysyl-tRNA Synthetases for Structurally Diverse Non-Canonical Amino Acids

ACS chemical biology, 2022-12, Vol.17 (12), p.3458-3469

2022

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Studies of Thioamide Effects on Serine Protease Activity Enable Two-Site Stabilization of Cancer Imaging Peptides

ACS chemical biology, 2020-03, Vol.15 (3), p.774-779

2020

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Alpha-synuclein from patient Lewy bodies exhibits distinct pathological activity that can be propagated in vitro

Acta neuropathologica communications, 2021-11, Vol.9 (1), p.188-188, Article 188

2021

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Semi-synthesis of thioamide containing proteins

Organic & biomolecular chemistry, 2015-05, Vol.13 (18), p.574-581

2015

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Thioamide quenching of intrinsic protein fluorescence

Chemical communications (Cambridge, England), 2012-02, Vol.48 (10), p.1550-1552

2012

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Identification of a Putative α-synuclein Radioligand Using an in silico Similarity Search

Molecular imaging and biology, 2023-08, Vol.25 (4), p.704-719

2023

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Evaluation of Diagnostic Accuracy Following the Coadministration of Delta-Aminolevulinic Acid and Second Window Indocyanine Green in Rodent and Human Glioblastomas

Molecular imaging and biology, 2020-10, Vol.22 (5), p.1266-1279

2020

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Comparison of strategies for non-perturbing labeling of α-synuclein to study amyloidogenesis

Organic & biomolecular chemistry, 2016-02, Vol.14 (5), p.1584-1592

2016

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The molecular basis for the synergistic aggregation of tau by alpha-synuclein

Biophysical journal, 2023-02, Vol.122 (3), p.200a-201a

2023

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Improving target amino acid selectivity in a permissive aminoacyl tRNA synthetase through counter-selection

Organic & biomolecular chemistry, 2017-05, Vol.15 (17), p.3603-3610

2017

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Rational design of small molecule fluorescent probes for biological applications

New strategies for fluorescently labeling proteins in the study of amyloids

Biosynthesis and Chemical Applications of Thioamides

Scalable thioarylation of unprotected peptides and biomolecules under Ni/photoredox catalysis

Molecular basis for N-terminal acetylation by the heterodimeric NatA complex

Thioamide Substitution Selectively Modulates Proteolysis and Receptor Activity of Therapeutic Peptide Hormones

Post-translational modifications of soluble α-synuclein regulate the amplification of pathological α-synuclein

Insights into genome recoding from the mechanism of a classic +1-frameshifting tRNA

Molecular basis for N-terminal alpha-synuclein acetylation by human NatB

Rosetta custom score functions accurately predict ΔΔG of mutations at protein-protein interfaces using machine learning

Optimization of Second Window Indocyanine Green for Intraoperative Near-Infrared Imaging of Thoracic Malignancy

Multiply labeling proteins for studies of folding and stability

Rational design of thioamide peptides as selective inhibitors of cysteine protease cathepsin L

Efficient synthesis and in vivo incorporation of acridon-2-ylalanine, a fluorescent amino acid for lifetime and Förster resonance energy transfer/luminescence resonance energy transfer studies

An improved fluorescent noncanonical amino acid for measuring conformational distributions using time-resolved transition metal ion FRET

Generating Efficient Methanomethylophilus alvus Pyrrolysyl-tRNA Synthetases for Structurally Diverse Non-Canonical Amino Acids

Studies of Thioamide Effects on Serine Protease Activity Enable Two-Site Stabilization of Cancer Imaging Peptides

Alpha-synuclein from patient Lewy bodies exhibits distinct pathological activity that can be propagated in vitro

Semi-synthesis of thioamide containing proteins

Thioamide quenching of intrinsic protein fluorescence

Identification of a Putative α-synuclein Radioligand Using an in silico Similarity Search

Evaluation of Diagnostic Accuracy Following the Coadministration of Delta-Aminolevulinic Acid and Second Window Indocyanine Green in Rodent and Human Glioblastomas

Comparison of strategies for non-perturbing labeling of α-synuclein to study amyloidogenesis

The molecular basis for the synergistic aggregation of tau by alpha-synuclein

Improving target amino acid selectivity in a permissive aminoacyl tRNA synthetase through counter-selection

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