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N -Acetyl-3-aminopyrazoles block the non-canonical NF-kB cascade by selectively inhibiting NIK

MedChemComm, 2018, Vol.9 (6), p.963-968

2018

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Discovery, Structure–Activity Relationship, and Antiparkinsonian Effect of a Potent and Brain-Penetrant Chemical Series of Positive Allosteric Modulators of Metabotropic Glutamate Receptor 4

Journal of medicinal chemistry, 2017-10, Vol.60 (20), p.8515-8537

2017

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Discovery of BNC375, a Potent, Selective, and Orally Available Type I Positive Allosteric Modulator of α7 nAChRs

ACS medicinal chemistry letters, 2019-05, Vol.10 (5), p.754-760

2019

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Porphyrin Derivatives Inhibit the Interaction between Receptor Activator of NF-[kappa]B and Its Ligand

ChemMedChem, 2017-10, Vol.12 (20), p.1697

2017

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4-Hydroxy- N -[3,5-bis(trifluoromethyl)phenyl]-1,2,5-thiadiazole-3-carboxamide: a novel inhibitor of the canonical NF-κB cascade

MedChemComm, 2017-09, Vol.8 (9), p.1850-1855

2017

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Porphyrin Derivatives Inhibit the Interaction between Receptor Activator of NF‐κB and Its Ligand

ChemMedChem, 2017-10, Vol.12 (20), p.1697-1702

2017

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N-Acetyl-3-aminopyrazoles block the non-canonical NF-kB cascade by selectively inhibiting NIKElectronic supplementary information (ESI) available: Additional biochemical data, chemistry, NMR characterization of final compounds, and biochemical protocols. See DOI: 10.1039/c8md00068a

2018-06

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N-Acetyl-3-aminopyrazoles block the non-canonical NF-kB cascade by selectively inhibiting NIK† †Electronic supplementary information (ESI) available: Additional biochemical data, chemistry, NMR characterization of final compounds, and biochemical protocols. See DOI: 10.1039/c8md00068a

MedChemComm, 2018-04, Vol.9 (6), p.963-968

2018

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Fragment pharmacophore-based in silico screening: a powerful approach for efficient lead discoveryThe authors declare no competing interests

2016-03

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Fragment pharmacophore-based in silicoscreening: a powerful approach for efficient lead discovery

MedChemComm, 2016-03, Vol.7 (3), p.506-511

2016

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Fragment pharmacophore-based in silico screening: a powerful approach for efficient lead discovery

MedChemComm, 2016-03, Vol.7 (3), p.506-511

2016

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4-Hydroxy-N-[3,5-bis(trifluoromethyl)phenyl]-1,2,5-thiadiazole-3-carboxamide: a novel inhibitor of the canonical NF-κB cascadeElectronic supplementary information (ESI) available: Additional biochemical data, chemistry, NMR characterization of final compounds, biochemical protocols. See DOI: 10.1039/c7md00278e

2017-09

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4-Hydroxy-N-[3,5-bis(trifluoromethyl)phenyl]-1,2,5-thiadiazole-3-carboxamide: a novel inhibitor of the canonical NF-κB cascade† †Electronic supplementary information (ESI) available: Additional biochemical data, chemistry, NMR characterization of final compounds, biochemical protocols. See DOI: 10.1039/c7md00278e

MedChemComm, 2017-08, Vol.8 (9), p.1850-1855

2017

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Structural, Magnetic, and Dynamic Characterization of the (d xz ,d y z )4(d x y )1 Ground-State Low-Spin Iron(III) Tetraphenylporphyrinate Complex [(p-TTP)Fe(2,6-XylylNC)2]CF3SO3

Journal of the American Chemical Society, 2000-05, Vol.122 (18), p.4366-4377

2000

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Synthesis and Characterization of Low-Spin Bis(amino ester) Iron(III) Porphyrin Complexes

Inorganic chemistry, 1998-11, Vol.37 (23), p.6100-6103

1998

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Oxidation of amino esters to imine complexes with chiral high-valent oxoruthenium porphyrins

Inorganica Chimica Acta, 1998-05, Vol.273 (1), p.142-150

1998

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Chapter 9 - Ring Transformations

The Practice of Medicinal Chemistry, 2015, p.243-266

Fourth Edition, 2015

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Structural, Magnetic, and Dynamic Characterization of the (d xz ,d y z ) 4 (d x y ) 1 Ground-State Low-Spin Iron(III) Tetraphenylporphyrinate Complex [( p -TTP)Fe(2,6-XylylNC) 2 ]CF 3 SO 3

Journal of the American Chemical Society, 2000-05, Vol.122 (18), p.4366-4377

2000

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Chapter 16 - Ring Transformations

The Practice of Medicinal Chemistry, 2008, p.343-362

Third Edition, 2008

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Ring Transformations

Practice of Medicinal Chemistry, 2008, p.1-1

Wermuth Camille Georges

3rd Edition, 2008

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ChemInform Abstract: Palladium Assisted Substitution of 3-Benzo[b]furan Triflates

ChemInform, 2002-07, Vol.33 (28), p.no-no

2002

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ChemInform Abstract: Synthesis of Constrained Arylpiperidines Using Intramolecular Heck or Radical Reactions

ChemInform, 2002-01, Vol.33 (2), p.no-no

2002

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Novel allenylidene alkynyl and ammonia alkynyl metal complexes via selective synthesis of mono and bis alkynyl ruthenium(II) complexes ; crystal structure of trans-[Ru(NH3)(C≡CPh)(Ph2PCH2CH2PPh2)2]PF6

Journal of the Chemical Society. Chemical communications, 1994 (7), p.859-860

1994

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Novel allenylidene alkynyl and ammonia alkynyl metal complexes via selective synthesis of mono and bis alkynyl ruthenium( II ) complexes; crystal structure of trans-[Ru(NH 3 )(CCPh)(Ph 2 PCH 2 CH 2 PPh 2 ) 2 ]PF 6

Journal of the Chemical Society. Chemical communications, 1994 (7), p.859-860

1994

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Cyclosporine before PCI in Patients with Acute Myocardial Infarction

The New England journal of medicine, 2015-09, Vol.373 (11), p.1021-1031

2015

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N -Acetyl-3-aminopyrazoles block the non-canonical NF-kB cascade by selectively inhibiting NIK

Discovery, Structure–Activity Relationship, and Antiparkinsonian Effect of a Potent and Brain-Penetrant Chemical Series of Positive Allosteric Modulators of Metabotropic Glutamate Receptor 4

Discovery of BNC375, a Potent, Selective, and Orally Available Type I Positive Allosteric Modulator of α7 nAChRs

Porphyrin Derivatives Inhibit the Interaction between Receptor Activator of NF-[kappa]B and Its Ligand

4-Hydroxy- N -[3,5-bis(trifluoromethyl)phenyl]-1,2,5-thiadiazole-3-carboxamide: a novel inhibitor of the canonical NF-κB cascade

Porphyrin Derivatives Inhibit the Interaction between Receptor Activator of NF‐κB and Its Ligand

N-Acetyl-3-aminopyrazoles block the non-canonical NF-kB cascade by selectively inhibiting NIKElectronic supplementary information (ESI) available: Additional biochemical data, chemistry, NMR characterization of final compounds, and biochemical protocols. See DOI: 10.1039/c8md00068a

N-Acetyl-3-aminopyrazoles block the non-canonical NF-kB cascade by selectively inhibiting NIK† †Electronic supplementary information (ESI) available: Additional biochemical data, chemistry, NMR characterization of final compounds, and biochemical protocols. See DOI: 10.1039/c8md00068a

Fragment pharmacophore-based in silico screening: a powerful approach for efficient lead discoveryThe authors declare no competing interests

Fragment pharmacophore-based in silicoscreening: a powerful approach for efficient lead discovery

Fragment pharmacophore-based in silico screening: a powerful approach for efficient lead discovery

Structural, Magnetic, and Dynamic Characterization of the (d xz ,d y z )4(d x y )1 Ground-State Low-Spin Iron(III) Tetraphenylporphyrinate Complex [(p-TTP)Fe(2,6-XylylNC)2]CF3SO3

Synthesis and Characterization of Low-Spin Bis(amino ester) Iron(III) Porphyrin Complexes

Oxidation of amino esters to imine complexes with chiral high-valent oxoruthenium porphyrins

Chapter 9 - Ring Transformations

Structural, Magnetic, and Dynamic Characterization of the (d xz ,d y z ) 4 (d x y ) 1 Ground-State Low-Spin Iron(III) Tetraphenylporphyrinate Complex [( p -TTP)Fe(2,6-XylylNC) 2 ]CF 3 SO 3

Chapter 16 - Ring Transformations

Ring Transformations

ChemInform Abstract: Palladium Assisted Substitution of 3-Benzo[b]furan Triflates

ChemInform Abstract: Synthesis of Constrained Arylpiperidines Using Intramolecular Heck or Radical Reactions

Novel allenylidene alkynyl and ammonia alkynyl metal complexes via selective synthesis of mono and bis alkynyl ruthenium(II) complexes ; crystal structure of trans-[Ru(NH3)(C≡CPh)(Ph2PCH2CH2PPh2)2]PF6

Novel allenylidene alkynyl and ammonia alkynyl metal complexes via selective synthesis of mono and bis alkynyl ruthenium( II ) complexes; crystal structure of trans-[Ru(NH 3 )(CCPh)(Ph 2 PCH 2 CH 2 PPh 2 ) 2 ]PF 6

Cyclosporine before PCI in Patients with Acute Myocardial Infarction

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