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Risk prediction of late-onset Alzheimer's disease implies an oligogenic architecture

Nature communications, 2020-09, Vol.11 (1), p.4799-4799, Article 4799

2020

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Motor and cognitive deficits in aged tau knockout mice in two background strains

Molecular neurodegeneration, 2014-08, Vol.9 (1), p.29-29, Article 29

2014

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An iron–dopamine index predicts risk of parkinsonian neurodegeneration in the substantia nigra pars compacta

Chemical science (Cambridge), 2014, Vol.5 (6), p.2160-2169

2014

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Increasing Cu bioavailability inhibits Aβ oligomers and tau phosphorylation

Proceedings of the National Academy of Sciences - PNAS, 2009-01, Vol.106 (2), p.381-386

2009

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Copper as a target for prostate cancer therapeutics: copper-ionophore pharmacology and altering systemic copper distribution

Oncotarget, 2016-06, Vol.7 (24), p.37064-37080

2016

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Presenilins Promote the Cellular Uptake of Copper and Zinc and Maintain Copper Chaperone of SOD1-dependent Copper/Zinc Superoxide Dismutase Activity

The Journal of biological chemistry, 2011-03, Vol.286 (11), p.9776-9786

2011

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Platinum-based inhibitors of amyloid-β as therapeutic agents for Alzheimer's disease

Proceedings of the National Academy of Sciences - PNAS, 2008-05, Vol.105 (19), p.6813-6818

2008

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Iron accumulation confers neurotoxicity to a vulnerable population of nigral neurons: implications for Parkinson's disease

Molecular neurodegeneration, 2014-07, Vol.9 (1), p.27-27, Article 27

2014

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Decreased Plasma Iron in Alzheimer’s Disease Is Due to Transferrin Desaturation

ACS chemical neuroscience, 2015-03, Vol.6 (3), p.398-402

2015

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Effects of Neonatal Iron Feeding and Chronic Clioquinol Administration on the Parkinsonian Human A53T Transgenic Mouse

ACS chemical neuroscience, 2016-03, Vol.7 (3), p.360-366

2016

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Cysteine Oxidation within N-terminal Mutant Huntingtin Promotes Oligomerization and Delays Clearance of Soluble Protein

The Journal of biological chemistry, 2011-05, Vol.286 (20), p.18320-18330

2011

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Copper and Zinc Binding Modulates the Aggregation and Neurotoxic Properties of the Prion Peptide PrP106−126

Biochemistry (Easton), 2001-07, Vol.40 (27), p.8073-8084

2001

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Manganese chelation therapy extends survival in a mouse model of M1000 prion disease

Journal of neurochemistry, 2010-07, Vol.114 (2), p.440-451

2010

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Deregulation of subcellular biometal homeostasis through loss of the metal transporter, Zip7, in a childhood neurodegenerative disorder

Acta neuropathologica communications, 2014-02, Vol.2 (1), p.25-25, Article 25

2014

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Apolipoprotein E ablation decreases synaptic vesicular zinc in the brain

Biometals, 2010-12, Vol.23 (6), p.1085-1095

2010

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Asymmetric thinning of the cerebral cortex across the adult lifespan is accelerated in Alzheimer's disease

Nature communications, 2021-02, Vol.12 (1), p.721-721, Article 721

2021

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Increased Risk of Cognitive Impairment in Patients With Diabetes Is Associated With Metformin

Diabetes care, 2013-10, Vol.36 (10), p.2981-2987

2013

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Impaired cellular copper regulation in the presence of ApoE4

Journal of neurochemistry, 2024-08

2024

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Amyloid-β, anxiety, and cognitive decline in preclinical Alzheimer disease: a multicenter, prospective cohort study

JAMA psychiatry (Chicago, Ill.), 2015-03, Vol.72 (3), p.284

2015

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The Alzheimer’s therapeutic PBT2 promotes amyloid‐β degradation and GSK3 phosphorylation via a metal chaperone activity

Journal of neurochemistry, 2011-10, Vol.119 (1), p.220-230

2011

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The Effects of Clioquinol on P-glycoprotein Expression and Biometal Distribution in the Mouse Brain Microvasculature

Journal of pharmaceutical sciences, 2019-07, Vol.108 (7), p.2247-2255

2019

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Alzheimer's Disease Amyloid-β Binds Copper and Zinc to Generate an Allosterically Ordered Membrane-penetrating Structure Containing Superoxide Dismutase-like Subunits

The Journal of biological chemistry, 2001-06, Vol.276 (23), p.20466-20473

2001

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A blood-based predictor for neocortical Aβ burden in Alzheimer's disease: results from the AIBL study

Molecular psychiatry, 2014-04, Vol.19 (4), p.519-526

2014

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Insights into Zn2+ homeostasis in neurons from experimental and modeling studies

American Journal of Physiology: Cell Physiology, 2008-03, Vol.294 (3), p.C726-C742

2008

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Hypoxia-inducible factor prolyl 4-hydroxylase inhibition. A target for neuroprotection in the central nervous system

The Journal of biological chemistry, 2005-12, Vol.280 (50), p.41732-41743

2005

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Risk prediction of late-onset Alzheimer's disease implies an oligogenic architecture

Motor and cognitive deficits in aged tau knockout mice in two background strains

An iron–dopamine index predicts risk of parkinsonian neurodegeneration in the substantia nigra pars compacta

Increasing Cu bioavailability inhibits Aβ oligomers and tau phosphorylation

Copper as a target for prostate cancer therapeutics: copper-ionophore pharmacology and altering systemic copper distribution

Presenilins Promote the Cellular Uptake of Copper and Zinc and Maintain Copper Chaperone of SOD1-dependent Copper/Zinc Superoxide Dismutase Activity

Platinum-based inhibitors of amyloid-β as therapeutic agents for Alzheimer's disease

Iron accumulation confers neurotoxicity to a vulnerable population of nigral neurons: implications for Parkinson's disease

Decreased Plasma Iron in Alzheimer’s Disease Is Due to Transferrin Desaturation

Effects of Neonatal Iron Feeding and Chronic Clioquinol Administration on the Parkinsonian Human A53T Transgenic Mouse

Cysteine Oxidation within N-terminal Mutant Huntingtin Promotes Oligomerization and Delays Clearance of Soluble Protein

Copper and Zinc Binding Modulates the Aggregation and Neurotoxic Properties of the Prion Peptide PrP106−126

Manganese chelation therapy extends survival in a mouse model of M1000 prion disease

Deregulation of subcellular biometal homeostasis through loss of the metal transporter, Zip7, in a childhood neurodegenerative disorder

Apolipoprotein E ablation decreases synaptic vesicular zinc in the brain

Asymmetric thinning of the cerebral cortex across the adult lifespan is accelerated in Alzheimer's disease

Increased Risk of Cognitive Impairment in Patients With Diabetes Is Associated With Metformin

Impaired cellular copper regulation in the presence of ApoE4

Amyloid-β, anxiety, and cognitive decline in preclinical Alzheimer disease: a multicenter, prospective cohort study

The Alzheimer’s therapeutic PBT2 promotes amyloid‐β degradation and GSK3 phosphorylation via a metal chaperone activity

The Effects of Clioquinol on P-glycoprotein Expression and Biometal Distribution in the Mouse Brain Microvasculature

Alzheimer's Disease Amyloid-β Binds Copper and Zinc to Generate an Allosterically Ordered Membrane-penetrating Structure Containing Superoxide Dismutase-like Subunits

A blood-based predictor for neocortical Aβ burden in Alzheimer's disease: results from the AIBL study

Insights into Zn2+ homeostasis in neurons from experimental and modeling studies

Hypoxia-inducible factor prolyl 4-hydroxylase inhibition. A target for neuroprotection in the central nervous system

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