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PPARγ in bone homeostasis

Trends in endocrinology and metabolism, 2010-12, Vol.21 (12), p.722-728

Wan, Yihong

2010

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Mitochondrial Complex I Activity Suppresses Inflammation and Enhances Bone Resorption by Shifting Macrophage-Osteoclast Polarization

Cell metabolism, 2014-09, Vol.20 (3), p.483-498

2014

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Differential regulation of breast cancer bone metastasis by PARP1 and PARP2

Nature communications, 2020-03, Vol.11 (1), p.1578-10, Article 1578

2020

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Gpr132 sensing of lactate mediates tumor–macrophage interplay to promote breast cancer metastasis

Proceedings of the National Academy of Sciences - PNAS, 2017-01, Vol.114 (3), p.580-585

2017

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New therapeutic targets for cancer bone metastasis

Trends in pharmacological sciences (Regular ed.), 2015-06, Vol.36 (6), p.360-373

2015

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A Liver-Bone Endocrine Relay by IGFBP1 Promotes Osteoclastogenesis and Mediates FGF21-Induced Bone Resorption

Cell metabolism, 2015-11, Vol.22 (5), p.811-824

2015

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mTORC1 impedes osteoclast differentiation via calcineurin and NFATc1

Communications biology, 2018-01, Vol.1 (1), p.29-29, Article 29

2018

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High‐Contrast Fluorescence Detection of Metastatic Breast Cancer Including Bone and Liver Micrometastases via Size‐Controlled pH‐Activatable Water‐Soluble Probes

Advanced materials (Weinheim), 2017-08, Vol.29 (29), p.n/a

2017

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The starvation hormone, fibroblast growth factor-21, extends lifespan in mice

eLife, 2012-10, Vol.1, p.e00065-e00065

2012

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Opposing Functions of BRD4 Isoforms in Breast Cancer

Molecular cell, 2020-06, Vol.78 (6), p.1114-1132.e10

2020

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Fibroblast growth factor 21 promotes bone loss by potentiating the effects of peroxisome proliferator-activated receptor γ

Proceedings of the National Academy of Sciences - PNAS, 2012-02, Vol.109 (8), p.3143-3148

2012

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Macrophage PPARγ inhibits Gpr132 to mediate the anti-tumor effects of rosiglitazone

eLife, 2016-10, Vol.5

2016

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Neuronal and nonneuronal cholinergic structures in the mouse gastrointestinal tract and spleen

Journal of comparative neurology (1911), 2013-11, Vol.521 (16), p.3741-3767

2013

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Minireview: Nuclear Receptor Regulation of Osteoclast and Bone Remodeling

Molecular endocrinology (Baltimore, Md.), 2015-02, Vol.29 (2), p.172-186

2015

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Biphasic and Dosage-Dependent Regulation of Osteoclastogenesis by β-Catenin

Molecular and Cellular Biology, 2011-12, Vol.31 (23), p.4706-4719

2011

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Q63, a novel DENV2 RdRp non-nucleoside inhibitor, inhibited DENV2 replication and infection

Journal of pharmacological sciences, 2018-12, Vol.138 (4), p.247-256

2018

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Molecular determinants for the polarization of macrophage and osteoclast

Seminars in immunopathology, 2019-09, Vol.41 (5), p.551-563

2019

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mTOR Inhibition Subdues Milk Disorder Caused by Maternal VLDLR Loss

Cell reports (Cambridge), 2017-06, Vol.19 (10), p.2014-2025

2017

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Thiazolidinediones on PPARγ: The Roles in Bone Remodeling

PPAR Research, 2011-01, Vol.2011 (2011), p.189-197

2011

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Nur77 prevents excessive osteoclastogenesis by inducing ubiquitin ligase Cbl-b to mediate NFATc1 self-limitation

eLife, 2015-07, Vol.4, p.e07217-e07217

2015

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Maternal western diet causes inflammatory milk and TLR2/4-dependent neonatal toxicity

Genes & development, 2012-06, Vol.26 (12), p.1306-1311

2012

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Inhibition of myeloid PD-L1 suppresses osteoclastogenesis and cancer bone metastasis

Cancer gene therapy, 2022-10, Vol.29 (10), p.1342-1354

2022

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GLP-1 Receptor Activation Abrogates β-Cell Dysfunction by PKA Cα-Mediated Degradation of Thioredoxin Interacting Protein

Frontiers in pharmacology, 2019-10, Vol.10, p.1230-1230

2019

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Orexin Regulates Bone Remodeling via a Dominant Positive Central Action and a Subordinate Negative Peripheral Action

Cell metabolism, 2014-06, Vol.19 (6), p.927-940

2014

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Bone marrow mesenchymal stem cells: Fat on and blast off by FGF21

The international journal of biochemistry & cell biology, 2013-03, Vol.45 (3), p.546-549

Wan, Yihong

2013

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PPARγ in bone homeostasis

Mitochondrial Complex I Activity Suppresses Inflammation and Enhances Bone Resorption by Shifting Macrophage-Osteoclast Polarization

Differential regulation of breast cancer bone metastasis by PARP1 and PARP2

Gpr132 sensing of lactate mediates tumor–macrophage interplay to promote breast cancer metastasis

New therapeutic targets for cancer bone metastasis

A Liver-Bone Endocrine Relay by IGFBP1 Promotes Osteoclastogenesis and Mediates FGF21-Induced Bone Resorption

mTORC1 impedes osteoclast differentiation via calcineurin and NFATc1

High‐Contrast Fluorescence Detection of Metastatic Breast Cancer Including Bone and Liver Micrometastases via Size‐Controlled pH‐Activatable Water‐Soluble Probes

The starvation hormone, fibroblast growth factor-21, extends lifespan in mice

Opposing Functions of BRD4 Isoforms in Breast Cancer

Fibroblast growth factor 21 promotes bone loss by potentiating the effects of peroxisome proliferator-activated receptor γ

Macrophage PPARγ inhibits Gpr132 to mediate the anti-tumor effects of rosiglitazone

Neuronal and nonneuronal cholinergic structures in the mouse gastrointestinal tract and spleen

Minireview: Nuclear Receptor Regulation of Osteoclast and Bone Remodeling

Biphasic and Dosage-Dependent Regulation of Osteoclastogenesis by β-Catenin

Q63, a novel DENV2 RdRp non-nucleoside inhibitor, inhibited DENV2 replication and infection

Molecular determinants for the polarization of macrophage and osteoclast

mTOR Inhibition Subdues Milk Disorder Caused by Maternal VLDLR Loss

Thiazolidinediones on PPARγ: The Roles in Bone Remodeling

Nur77 prevents excessive osteoclastogenesis by inducing ubiquitin ligase Cbl-b to mediate NFATc1 self-limitation

Maternal western diet causes inflammatory milk and TLR2/4-dependent neonatal toxicity

Inhibition of myeloid PD-L1 suppresses osteoclastogenesis and cancer bone metastasis

GLP-1 Receptor Activation Abrogates β-Cell Dysfunction by PKA Cα-Mediated Degradation of Thioredoxin Interacting Protein

Orexin Regulates Bone Remodeling via a Dominant Positive Central Action and a Subordinate Negative Peripheral Action

Bone marrow mesenchymal stem cells: Fat on and blast off by FGF21

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