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Absorption, Disposition, Metabolism, and Excretion of [3-14C]Caffeic Acid in Rats

Journal of agricultural and food chemistry, 2012-05, Vol.60 (20), p.5205-5214

2012

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Seconds-Resolved, In Situ Measurements of Plasma Phenylalanine Disposition Kinetics in Living Rats

Analytical chemistry (Washington), 2021-03, Vol.93 (8), p.4023-4032

2021

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Na+/Taurocholate Cotransporting Polypeptide and Apical Sodium-Dependent Bile Acid Transporter Are Involved in the Disposition of Perfluoroalkyl Sulfonates in Humans and Rats

Toxicological sciences, 2015-08, Vol.146 (2), p.363-373

2015

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Factors determining the oral absorption and systemic disposition of zeaxanthin in rats: in vitro, in situ, and in vivo evaluations

Pharmaceutical biology, 2022-12, Vol.60 (1), p.2266-2275

2022

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Human and nonclinical disposition of [14C]bictegravir, a potent integrase strand-transfer inhibitor for the treatment of HIV-1 infection

Xenobiotica, 2022-11, Vol.52 (9-11), p.973-985

2022

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Mechanistic Basis of Cabotegravir-Glucuronide Disposition in Humans

The Journal of pharmacology and experimental therapeutics, 2019-08, Vol.370 (2), p.269-277

2019

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Morphine metabolism, transport and brain disposition

Metabolic brain disease, 2012-03, Vol.27 (1), p.1-5

2012

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Minimal Physiologically Based Pharmacokinetic-Pharmacodynamic (mPBPK-PD) Model of N -Acetylgalactosamine-Conjugated Small Interfering RNA Disposition and Gene Silencing in Preclinical Species and Humans

The Journal of pharmacology and experimental therapeutics, 2021-11, Vol.379 (2), p.134-146

2021

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Organic Anion Transporting Polypeptides Contribute to the Disposition of Perfluoroalkyl Acids in Humans and Rats

Toxicological sciences, 2017-03, Vol.156 (1), p.84-95

2017

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Defining the Intravital Renal Disposition of Fluorescence-Quenched Exenatide

Molecular pharmaceutics, 2023-02, Vol.20 (2), p.987-996

2023

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Pharmacokinetics and Disposition of Contezolid in Humans: Resolution of a Disproportionate Human Metabolite for Clinical Development

Antimicrobial agents and chemotherapy, 2021-10, Vol.65 (11), p.e0040921

2021

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Metabolic disposition of the EGFR covalent inhibitor furmonertinib in humans

Acta pharmacologica Sinica, 2022-02, Vol.43 (2), p.494-503

2022

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Metabolism and disposition of [14C]tivantinib after oral administration to humans, dogs and rats

Xenobiotica, 2014-11, Vol.44 (11), p.996-1008

2014

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Towards a platform PBPK model to characterize the plasma and tissue disposition of monoclonal antibodies in preclinical species and human

Journal of pharmacokinetics and pharmacodynamics, 2012-02, Vol.39 (1), p.67-86

2012

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Mechanistic basis of altered morphine disposition in nonalcoholic steatohepatitis

The Journal of pharmacology and experimental therapeutics, 2015-03, Vol.352 (3), p.462-470

2015

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Age-and Region-Dependent Disposition of Raloxifene in Rats

Pharmaceutical research, 2021-08, Vol.38 (8), p.1357-1367

2021

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physiologically‐based pharmacokinetic model for disposition of 2,3,7,8‐TCDD in fathead minnow and medaka

Environmental toxicology and chemistry, 2014-05, Vol.33 (5), p.1064-1071

2014

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Disposition of perfluorinated acid isomers in Sprague-Dawley rats; Part 1: Single dose

Environmental toxicology and chemistry, 2009-03, Vol.28 (3), p.542-554

2009

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Metabolic disposition of the anti-cancer agent [14C]laromustine in male rats

Xenobiotica, 2015-08, Vol.45 (8), p.711-721

2015

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A “middle‐out approach” for the prediction of human drug disposition from preclinical data using simplified physiologically based pharmacokinetic (PBPK) models

CPT: pharmacometrics and systems pharmacology, 2023-03, Vol.12 (3), p.346-359

2023

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Pharmacokinetics and disposition of anlotinib, an oral tyrosine kinase inhibitor, in experimental animal species

Acta pharmacologica Sinica, 2018-06, Vol.39 (6), p.1048-1063

2018

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Hepatic organic anion transporting polypeptides mediate disposition of milk thistle flavonolignans and pharmacokinetic silymarin‐drug interactions

Phytotherapy research, 2021-06, Vol.35 (6), p.3286-3297

2021

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Pharmacokinetics and Tumor Disposition of PEGylated, Methotrexate Conjugated Poly-l-lysine Dendrimers

Molecular pharmaceutics, 2009-08, Vol.6 (4), p.1190-1204

2009

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A translational platform PBPK model for antibody disposition in the brain

Journal of pharmacokinetics and pharmacodynamics, 2019-08, Vol.46 (4), p.319-338

2019

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Sinusoidal Organic Anion-Transporting Polypeptide 1B1/1B3 and Bile Canalicular Multidrug Resistance-Associated Protein 2 Play an Essential Role in the Hepatobiliary Disposition of a Synthetic Cyclic Dinucleotide (STING Agonist)

The AAPS journal, 2022-09, Vol.24 (6), p.99, Article 99

2022

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Absorption, Disposition, Metabolism, and Excretion of [3-14C]Caffeic Acid in Rats

Seconds-Resolved, In Situ Measurements of Plasma Phenylalanine Disposition Kinetics in Living Rats

Na+/Taurocholate Cotransporting Polypeptide and Apical Sodium-Dependent Bile Acid Transporter Are Involved in the Disposition of Perfluoroalkyl Sulfonates in Humans and Rats

Factors determining the oral absorption and systemic disposition of zeaxanthin in rats: in vitro, in situ, and in vivo evaluations

Human and nonclinical disposition of [14C]bictegravir, a potent integrase strand-transfer inhibitor for the treatment of HIV-1 infection

Mechanistic Basis of Cabotegravir-Glucuronide Disposition in Humans

Morphine metabolism, transport and brain disposition

Minimal Physiologically Based Pharmacokinetic-Pharmacodynamic (mPBPK-PD) Model of N -Acetylgalactosamine-Conjugated Small Interfering RNA Disposition and Gene Silencing in Preclinical Species and Humans

Organic Anion Transporting Polypeptides Contribute to the Disposition of Perfluoroalkyl Acids in Humans and Rats

Defining the Intravital Renal Disposition of Fluorescence-Quenched Exenatide

Pharmacokinetics and Disposition of Contezolid in Humans: Resolution of a Disproportionate Human Metabolite for Clinical Development

Metabolic disposition of the EGFR covalent inhibitor furmonertinib in humans

Metabolism and disposition of [14C]tivantinib after oral administration to humans, dogs and rats

Towards a platform PBPK model to characterize the plasma and tissue disposition of monoclonal antibodies in preclinical species and human

Mechanistic basis of altered morphine disposition in nonalcoholic steatohepatitis

Age-and Region-Dependent Disposition of Raloxifene in Rats

physiologically‐based pharmacokinetic model for disposition of 2,3,7,8‐TCDD in fathead minnow and medaka

Disposition of perfluorinated acid isomers in Sprague-Dawley rats; Part 1: Single dose

Metabolic disposition of the anti-cancer agent [14C]laromustine in male rats

A “middle‐out approach” for the prediction of human drug disposition from preclinical data using simplified physiologically based pharmacokinetic (PBPK) models

Pharmacokinetics and disposition of anlotinib, an oral tyrosine kinase inhibitor, in experimental animal species

Hepatic organic anion transporting polypeptides mediate disposition of milk thistle flavonolignans and pharmacokinetic silymarin‐drug interactions

Pharmacokinetics and Tumor Disposition of PEGylated, Methotrexate Conjugated Poly-l-lysine Dendrimers

A translational platform PBPK model for antibody disposition in the brain

Sinusoidal Organic Anion-Transporting Polypeptide 1B1/1B3 and Bile Canalicular Multidrug Resistance-Associated Protein 2 Play an Essential Role in the Hepatobiliary Disposition of a Synthetic Cyclic Dinucleotide (STING Agonist)

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