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PI3Kγ inhibition suppresses microglia/TAM accumulation in glioblastoma microenvironment to promote exceptional temozolomide response

Proceedings of the National Academy of Sciences - PNAS, 2021-04, Vol.118 (16), p.1

2021

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Glycolysis fuels phosphoinositide 3-kinase signaling to bolster T cell immunity

Science (American Association for the Advancement of Science), 2021-01, Vol.371 (6527), p.405-410

2021

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Class I PI3K-mediated Akt and ERK signals play a critical role in FcεRI-induced degranulation in mast cells

International immunology, 2013-04, Vol.25 (4), p.215-220

2013

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PI3Kγ is a molecular switch that controls immune suppression

Nature (London), 2016-11, Vol.539 (7629), p.437-442

2016

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Double PIK3CA mutations in cis increase oncogenicity and sensitivity to PI3Kα inhibitors

Science (American Association for the Advancement of Science), 2019-11, Vol.366 (6466), p.714-723

2019

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Non-catalytic role of phosphoinositide 3-kinase in mesenchymal cell migration through non-canonical induction of p85β/AP2-mediated endocytosis

Nature communications, 2024-03, Vol.15 (1), p.2612-2612

2024

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Phosphoinositide 3-kinase inhibitors induce DNA damage through nucleoside depletion

Proceedings of the National Academy of Sciences - PNAS, 2016-07, Vol.113 (30), p.E4338-E4347

2016

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Resveratrol inhibits LPS-induced MAPKs activation via activation of the phosphatidylinositol 3-kinase pathway in murine RAW 264.7 macrophage cells

PloS one, 2012-08, Vol.7 (8), p.e44107

2012

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Palmatine Derivatives as Potential Antiplatelet Aggregation Agents via Protein Kinase G/Vasodilator-Stimulated Phosphoprotein and Phosphatidylinositol 3‑Kinase/Akt Phosphorylation

Journal of medicinal chemistry, 2022-05, Vol.65 (10), p.7399-7413

2022

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Phosphoinositide 3-kinase p110δ promotes lumen formation through the enhancement of apico-basal polarity and basal membrane organization

Nature communications, 2015-01, Vol.6 (1), p.5937-5937, Article 5937

2015

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A molecular mechanism of artemisinin resistance in Plasmodium falciparum malaria

Nature (London), 2015-04, Vol.520 (7549), p.683-687

2015

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Characterisation of a cyclic peptide that binds to the RAS binding domain of phosphoinositide 3-kinase p110α

Scientific reports, 2023-02, Vol.13 (1), p.1889-1889, Article 1889

2023

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Oncogenic activity of the regulatory subunit p85β of phosphatidylinositol 3-kinase (PI3K)

Proceedings of the National Academy of Sciences - PNAS, 2014-11, Vol.111 (47), p.16826-16829

2014

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Prostaglandin E2 Promotes Colorectal Cancer Stem Cell Expansion and Metastasis in Mice

Gastroenterology (New York, N.Y. 1943), 2015-12, Vol.149 (7), p.1884-1895.e4

2015

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Vascular endothelial growth factor receptor-3 directly interacts with phosphatidylinositol 3-kinase to regulate lymphangiogenesis

PloS one, 2012-06, Vol.7 (6), p.e39558-e39558

2012

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The Oncogenic PI3K-Induced Transcriptomic Landscape Reveals Key Functions in Splicing and Gene Expression Regulation

Cancer research (Chicago, Ill.), 2022-06, Vol.82 (12), p.2269-2280

2022

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MiR-503 modulates epithelial-mesenchymal transition in silica-induced pulmonary fibrosis by targeting PI3K p85 and is sponged by lncRNA MALAT1

Scientific reports, 2017-09, Vol.7 (1), p.11313-15, Article 11313

2017

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The Role of the LY294002 - A Non-Selective Inhibitor of Phosphatidylinositol 3-Kinase (PI3K) Pathway- in Cell Survival and Proliferation in Cell Line SCC-25

Asian Pacific journal of cancer prevention : APJCP, 2019-11, Vol.20 (11), p.3377-3383

2019

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AMP-Activated Protein Kinase Regulates Neuronal Polarization by Interfering with PI 3-Kinase Localization

Science (American Association for the Advancement of Science), 2011-04, Vol.332 (6026), p.247-251

2011

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Qizhi Jiangtang capsule activates podocyte autophagy in diabetic kidney disease by inhibiting phosphatidylinositol 3-kinase/protein kinase B/mammalian target of rapamycin pathways

Journal of traditional Chinese medicine, 2023-08, Vol.43 (4), p.667-675

2023

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Role and regulation of phosphatidylinositol 3-kinase β in platelet integrin α2β1 signaling

Blood, 2012-01, Vol.119 (3), p.847-856

2012

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Autophagy mediates the delivery of thrombogenic tissue factor to neutrophil extracellular traps in human sepsis

PloS one, 2012-09, Vol.7 (9), p.e45427-e45427

2012

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Absence of signaling into CD4⁺ cells via C3aR and C5aR enables autoinductive TGF-β1 signaling and induction of Foxp3⁺ regulatory T cells

Nature immunology, 2013-02, Vol.14 (2), p.162

2013

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Phosphatidylinositol 3-kinase plays a vital role in regulation of rice seed vigor via altering NADPH oxidase activity

PloS one, 2012-03, Vol.7 (3), p.e33817

2012

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PIK3CA C-terminal frameshift mutations are novel oncogenic events that sensitize tumors to PI3K-α inhibition

Proceedings of the National Academy of Sciences - PNAS, 2020-09, Vol.117 (39), p.24427-24433

2020

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PI3Kγ inhibition suppresses microglia/TAM accumulation in glioblastoma microenvironment to promote exceptional temozolomide response

Glycolysis fuels phosphoinositide 3-kinase signaling to bolster T cell immunity

Class I PI3K-mediated Akt and ERK signals play a critical role in FcεRI-induced degranulation in mast cells

PI3Kγ is a molecular switch that controls immune suppression

Double PIK3CA mutations in cis increase oncogenicity and sensitivity to PI3Kα inhibitors

Non-catalytic role of phosphoinositide 3-kinase in mesenchymal cell migration through non-canonical induction of p85β/AP2-mediated endocytosis

Phosphoinositide 3-kinase inhibitors induce DNA damage through nucleoside depletion

Resveratrol inhibits LPS-induced MAPKs activation via activation of the phosphatidylinositol 3-kinase pathway in murine RAW 264.7 macrophage cells

Palmatine Derivatives as Potential Antiplatelet Aggregation Agents via Protein Kinase G/Vasodilator-Stimulated Phosphoprotein and Phosphatidylinositol 3‑Kinase/Akt Phosphorylation

Phosphoinositide 3-kinase p110δ promotes lumen formation through the enhancement of apico-basal polarity and basal membrane organization

A molecular mechanism of artemisinin resistance in Plasmodium falciparum malaria

Characterisation of a cyclic peptide that binds to the RAS binding domain of phosphoinositide 3-kinase p110α

Oncogenic activity of the regulatory subunit p85β of phosphatidylinositol 3-kinase (PI3K)

Prostaglandin E2 Promotes Colorectal Cancer Stem Cell Expansion and Metastasis in Mice

Vascular endothelial growth factor receptor-3 directly interacts with phosphatidylinositol 3-kinase to regulate lymphangiogenesis

The Oncogenic PI3K-Induced Transcriptomic Landscape Reveals Key Functions in Splicing and Gene Expression Regulation

MiR-503 modulates epithelial-mesenchymal transition in silica-induced pulmonary fibrosis by targeting PI3K p85 and is sponged by lncRNA MALAT1

The Role of the LY294002 - A Non-Selective Inhibitor of Phosphatidylinositol 3-Kinase (PI3K) Pathway- in Cell Survival and Proliferation in Cell Line SCC-25

AMP-Activated Protein Kinase Regulates Neuronal Polarization by Interfering with PI 3-Kinase Localization

Qizhi Jiangtang capsule activates podocyte autophagy in diabetic kidney disease by inhibiting phosphatidylinositol 3-kinase/protein kinase B/mammalian target of rapamycin pathways

Role and regulation of phosphatidylinositol 3-kinase β in platelet integrin α2β1 signaling

Autophagy mediates the delivery of thrombogenic tissue factor to neutrophil extracellular traps in human sepsis

Absence of signaling into CD4⁺ cells via C3aR and C5aR enables autoinductive TGF-β1 signaling and induction of Foxp3⁺ regulatory T cells

Phosphatidylinositol 3-kinase plays a vital role in regulation of rice seed vigor via altering NADPH oxidase activity

PIK3CA C-terminal frameshift mutations are novel oncogenic events that sensitize tumors to PI3K-α inhibition

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