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GLUT3 inhibitor discovery through in silico ligand screening and in vivo validation in eukaryotic expression systems

Scientific reports, 2022-01, Vol.12 (1), p.1429-1429, Article 1429

2022

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Screening for Glucose Perturbations and Risk Factor Management in Dysglycemic Patients With Coronary Artery Disease-A Persistent Challenge in Need of Substantial Improvement: A Report From ESC EORP EUROASPIRE V

Diabetes care, 2020-04, Vol.43 (4), p.726-733

2020

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Editorial on “Quantification of Cerebral Glucose Concentrations via Detection of the H1‐α‐Glucose Peak in 1H MRS at 7T”

Journal of magnetic resonance imaging, 2024-02, Vol.59 (2), p.673-674

2024

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A First-in-Human Study of GLY-200, an Oral, Gut- Restricted, Pharmacologic Duodenal Exclusion Therapy

Obesity (Silver Spring, Md.), 2022-11, Vol.30, p.19-19

2022

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Sodium‐glucose co‐transporter (SGLT) and glucose transporter (GLUT) expression in the kidney of type 2 diabetic subjects

Diabetes, obesity & metabolism, 2017-09, Vol.19 (9), p.1322-1326

2017

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The protein family of glucose transport facilitators: It's not only about glucose after all

IUBMB life, 2010-05, Vol.62 (5), p.315-333

Augustin, Robert

2010

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SGLT2 inhibition and renal urate excretion: role of luminal glucose, GLUT9, and URAT1

American journal of physiology. Renal physiology, 2019-01, Vol.316 (1), p.F173-F185

2019

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What does sodium‐glucose co‐transporter 1 inhibition add: Prospects for dual inhibition

Diabetes, obesity & metabolism, 2019-04, Vol.21 (S2), p.43-52

2019

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Comparative study of expression and activity of glucose transporters between stem cell-derived brain microvascular endothelial cells and hCMEC/D3 cells

American Journal of Physiology: Cell Physiology, 2017-10, Vol.313 (4), p.C421-C429

Al-Ahmad, Abraham J

2017

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1-deoxynojirimycin inhibits glucose absorption and accelerates glucose metabolism in streptozotocin-induced diabetic mice

Scientific reports, 2013-03, Vol.3 (1), p.1377, Article 1377

2013

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Structural basis of inhibition of the human SGLT2-MAP17 glucose transporter

Nature (London), 2022-01, Vol.601 (7892), p.280-284

2022

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Small‐Molecule Inhibition of Glucose Transporters GLUT‐1–4

Chembiochem : a European journal of chemical biology, 2020-01, Vol.21 (1-2), p.45-52

2020

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Natural Products as Lead Compounds for Sodium Glucose Cotransporter (SGLT) Inhibitors

Planta medica, 2017-08, Vol.83 (12-13), p.985-993

Blaschek, Wolfgang

2017

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Increase in SGLT1-mediated transport explains renal glucose reabsorption during genetic and pharmacological SGLT2 inhibition in euglycemia

American journal of physiology. Renal physiology, 2014-01, Vol.306 (2), p.F188-F193

2014

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In Vitro and In Vivo Inhibition of Intestinal Glucose Transport by Guava (Psidium Guajava) Extracts

Molecular nutrition & food research, 2018-06, Vol.62 (11), p.e1701012-n/a

2018

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Insulin secretion and action in subjects with impaired fasting glucose and impaired glucose tolerance : Results from the veterans administration genetic epidemiology study

Diabetes (New York, N.Y.), 2006-05, Vol.55 (5), p.1430-1435

2006

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Effects of SGLT2 inhibition in human kidney proximal tubular cells--renoprotection in diabetic nephropathy?

PloS one, 2013-02, Vol.8 (2), p.e54442

2013

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Oral glucose tolerance test is needed for appropriate classification of glucose regulation in patients with coronary artery disease: a report from the Euro Heart Survey on Diabetes and the Heart

Heart (British Cardiac Society), 2007-01, Vol.93 (1), p.72-77

2007

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Glucose Management Indicator (GMI): A New Term for Estimating A1C From Continuous Glucose Monitoring

Diabetes care, 2018-11, Vol.41 (11), p.2275-2280

2018

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Cystine transporter regulation of pentose phosphate pathway dependency and disulfide stress exposes a targetable metabolic vulnerability in cancer

Nature cell biology, 2020-04, Vol.22 (4), p.476-486

2020

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Do sodium‐glucose co‐transporter‐2 inhibitors increase plasma glucagon by direct actions on the alpha cell? And does the increase matter for the associated increase in endogenous glucose production?

Diabetes, obesity & metabolism, 2021-09, Vol.23 (9), p.2009-2019

2021

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Hyperglycemia drives intestinal barrier dysfunction and risk for enteric infection

Science (American Association for the Advancement of Science), 2018-03, Vol.359 (6382), p.1376-1383

2018

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Dapagliflozin improves insulin resistance and glucose intolerance in a novel transgenic rat model of chronic glucose overproduction and glucose toxicity

Diabetes, obesity & metabolism, 2017-08, Vol.19 (8), p.1135-1146

2017

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Understanding the clinical implications of differences between glucose management indicator and glycated haemoglobin

Diabetes, obesity & metabolism, 2022-04, Vol.24 (4), p.599-608

2022

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The Gut Microbiota in Prediabetes and Diabetes: A Population-Based Cross-Sectional Study

Cell metabolism, 2020-09, Vol.32 (3), p.379-390.e3

2020

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GLUT3 inhibitor discovery through in silico ligand screening and in vivo validation in eukaryotic expression systems

Screening for Glucose Perturbations and Risk Factor Management in Dysglycemic Patients With Coronary Artery Disease-A Persistent Challenge in Need of Substantial Improvement: A Report From ESC EORP EUROASPIRE V

Editorial on “Quantification of Cerebral Glucose Concentrations via Detection of the H1‐α‐Glucose Peak in 1H MRS at 7T”

A First-in-Human Study of GLY-200, an Oral, Gut- Restricted, Pharmacologic Duodenal Exclusion Therapy

Sodium‐glucose co‐transporter (SGLT) and glucose transporter (GLUT) expression in the kidney of type 2 diabetic subjects

The protein family of glucose transport facilitators: It's not only about glucose after all

SGLT2 inhibition and renal urate excretion: role of luminal glucose, GLUT9, and URAT1

What does sodium‐glucose co‐transporter 1 inhibition add: Prospects for dual inhibition

Comparative study of expression and activity of glucose transporters between stem cell-derived brain microvascular endothelial cells and hCMEC/D3 cells

1-deoxynojirimycin inhibits glucose absorption and accelerates glucose metabolism in streptozotocin-induced diabetic mice

Structural basis of inhibition of the human SGLT2-MAP17 glucose transporter

Small‐Molecule Inhibition of Glucose Transporters GLUT‐1–4

Natural Products as Lead Compounds for Sodium Glucose Cotransporter (SGLT) Inhibitors

Increase in SGLT1-mediated transport explains renal glucose reabsorption during genetic and pharmacological SGLT2 inhibition in euglycemia

In Vitro and In Vivo Inhibition of Intestinal Glucose Transport by Guava (Psidium Guajava) Extracts

Insulin secretion and action in subjects with impaired fasting glucose and impaired glucose tolerance : Results from the veterans administration genetic epidemiology study

Effects of SGLT2 inhibition in human kidney proximal tubular cells--renoprotection in diabetic nephropathy?

Oral glucose tolerance test is needed for appropriate classification of glucose regulation in patients with coronary artery disease: a report from the Euro Heart Survey on Diabetes and the Heart

Glucose Management Indicator (GMI): A New Term for Estimating A1C From Continuous Glucose Monitoring

Cystine transporter regulation of pentose phosphate pathway dependency and disulfide stress exposes a targetable metabolic vulnerability in cancer

Do sodium‐glucose co‐transporter‐2 inhibitors increase plasma glucagon by direct actions on the alpha cell? And does the increase matter for the associated increase in endogenous glucose production?

Hyperglycemia drives intestinal barrier dysfunction and risk for enteric infection

Dapagliflozin improves insulin resistance and glucose intolerance in a novel transgenic rat model of chronic glucose overproduction and glucose toxicity

Understanding the clinical implications of differences between glucose management indicator and glycated haemoglobin

The Gut Microbiota in Prediabetes and Diabetes: A Population-Based Cross-Sectional Study

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