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Estrogen Activation of G-Protein–Coupled Estrogen Receptor 1 Regulates Phosphoinositide 3-Kinase and mTOR Signaling to Promote Liver Growth in Zebrafish and Proliferation of Human Hepatocytes

Gastroenterology (New York, N.Y. 1943), 2019-05, Vol.156 (6), p.1788-1804.e13

2019

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PI3Kγ is a molecular switch that controls immune suppression

Nature (London), 2016-11, Vol.539 (7629), p.437-442

2016

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Solute Carrier Family 39 Member 6 Gene Promotes Aggressiveness of Esophageal Carcinoma Cells by Increasing Intracellular Levels of Zinc, Activating Phosphatidylinositol 3-Kinase Signaling, and Up-regulating Genes That Regulate Metastasis

Gastroenterology (New York, N.Y. 1943), 2017-06, Vol.152 (8), p.1985-1997.e12

2017

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At a crossroads: how to translate the roles of PI3K in oncogenic and metabolic signalling into improvements in cancer therapy

Nature reviews. Clinical oncology, 2022-07, Vol.19 (7), p.471-485

2022

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Prostaglandin E2 Promotes Colorectal Cancer Stem Cell Expansion and Metastasis in Mice

Gastroenterology (New York, N.Y. 1943), 2015-12, Vol.149 (7), p.1884-1895.e4

2015

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C-Type Lectin-Like Receptor 2 Suppresses AKT Signaling and Invasive Activities of Gastric Cancer Cells by Blocking Expression of Phosphoinositide 3-Kinase Subunits

Gastroenterology (New York, N.Y. 1943), 2016-05, Vol.150 (5), p.1183-1195.e16

2016

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Cracking the context-specific PI3K signaling code

Science signaling, 2020-01, Vol.13 (613)

2020

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TGF-β promotes PI3K-AKT signaling and prostate cancer cell migration through the TRAF6-mediated ubiquitylation of p85α

Science signaling, 2017-07, Vol.10 (486)

2017

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Tyrosine phosphorylation of the Gα-interacting protein GIV promotes activation of phosphoinositide 3-kinase during cell migration

Science signaling, 2011-09, Vol.4 (192), p.ra64

2011

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TLR9 and beclin 1 crosstalk regulates muscle AMPK activation in exercise

Nature (London), 2020-02, Vol.578 (7796), p.605-609

2020

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A CRISPR screen targeting PI3K effectors identifies RASA3 as a negative regulator of LFA-1-mediated adhesion in T cells

Science signaling, 2022-07, Vol.15 (743), p.eabl9169

2022

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A class of highly selective inhibitors bind to an active state of PI3Kγ

Nature chemical biology, 2019-04, Vol.15 (4), p.348

2019

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Whole-exome sequencing combined with functional genomics reveals novel candidate driver cancer genes in endometrial cancer

Genome research, 2012-11, Vol.22 (11), p.2120

2012

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Isoalantolactone, a sesquiterpene lactone, induces apoptosis in SGC-7901 cells via mitochondrial and phosphatidylinositol 3-kinase/Akt signaling pathways

Archives of Pharmacal Research, 2013, 36(10), , pp.1262-1269

2013

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PI3Kβ controls immune evasion in PTEN-deficient breast tumours

Nature (London), 2023-05, Vol.617 (7959), p.139-146

2023

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Bone Morphogenetic Protein 4 Induces Differentiation of Colorectal Cancer Stem Cells and Increases Their Response to Chemotherapy in Mice

Gastroenterology (New York, N.Y. 1943), 2011, Vol.140 (1), p.297-309.e6

2011

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Current and Investigational Agents Targeting the Phosphoinositide 3‐Kinase Pathway

Pharmacotherapy, 2018-10, Vol.38 (10), p.1058-1067

2018

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PI3Kβ plays a critical role in neutrophil activation by immune complexes

Science signaling, 2011-04, Vol.4 (168), p.ra23

2011

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Phosphoinositide 3-kinase γ inhibits cardiac GSK-3 independently of Akt

Science signaling, 2013-01, Vol.6 (259), p.ra4

2013

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Effect of Alkylresorcinols on Autophagy, Migration, and Invasion of HepG2 Cells

Journal of food science, 2019-10, Vol.84 (10), p.3063-3068

2019

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Characterisation of the Phosphatidylinositol 3-Kinase Pathway in Non-Small Cell Lung Cancer Cells Isolated from Pleural Effusions

Oncology, 2016-01, Vol.90 (5), p.280-288

2016

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Mfge8 promotes obesity by mediating the uptake of dietary fats and serum fatty acids

Nature medicine, 2014-02, Vol.20 (2), p.175-183

2014

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Tanshinone IIA Regulates Synaptic Plasticity in Mg 2+ -Free-Induced Epileptic Hippocampal Neurons via the PI3K/Akt Signaling Pathway

Journal of integrative neuroscience, 2024-03, Vol.23 (3), p.61

2024

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The regulatory subunits of PI3Kγ control distinct neutrophil responses

Science signaling, 2015-01, Vol.8 (360), p.ra8

2015

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Estrogen Activation of G-Protein–Coupled Estrogen Receptor 1 Regulates Phosphoinositide 3-Kinase and mTOR Signaling to Promote Liver Growth in Zebrafish and Proliferation of Human Hepatocytes

PI3Kγ is a molecular switch that controls immune suppression

Solute Carrier Family 39 Member 6 Gene Promotes Aggressiveness of Esophageal Carcinoma Cells by Increasing Intracellular Levels of Zinc, Activating Phosphatidylinositol 3-Kinase Signaling, and Up-regulating Genes That Regulate Metastasis

At a crossroads: how to translate the roles of PI3K in oncogenic and metabolic signalling into improvements in cancer therapy

Prostaglandin E2 Promotes Colorectal Cancer Stem Cell Expansion and Metastasis in Mice

C-Type Lectin-Like Receptor 2 Suppresses AKT Signaling and Invasive Activities of Gastric Cancer Cells by Blocking Expression of Phosphoinositide 3-Kinase Subunits

Cracking the context-specific PI3K signaling code

TGF-β promotes PI3K-AKT signaling and prostate cancer cell migration through the TRAF6-mediated ubiquitylation of p85α

Tyrosine phosphorylation of the Gα-interacting protein GIV promotes activation of phosphoinositide 3-kinase during cell migration

TLR9 and beclin 1 crosstalk regulates muscle AMPK activation in exercise

A CRISPR screen targeting PI3K effectors identifies RASA3 as a negative regulator of LFA-1-mediated adhesion in T cells

A class of highly selective inhibitors bind to an active state of PI3Kγ

Whole-exome sequencing combined with functional genomics reveals novel candidate driver cancer genes in endometrial cancer

Isoalantolactone, a sesquiterpene lactone, induces apoptosis in SGC-7901 cells via mitochondrial and phosphatidylinositol 3-kinase/Akt signaling pathways

PI3Kβ controls immune evasion in PTEN-deficient breast tumours

Bone Morphogenetic Protein 4 Induces Differentiation of Colorectal Cancer Stem Cells and Increases Their Response to Chemotherapy in Mice

Current and Investigational Agents Targeting the Phosphoinositide 3‐Kinase Pathway

PI3Kβ plays a critical role in neutrophil activation by immune complexes

Phosphoinositide 3-kinase γ inhibits cardiac GSK-3 independently of Akt

Effect of Alkylresorcinols on Autophagy, Migration, and Invasion of HepG2 Cells

Characterisation of the Phosphatidylinositol 3-Kinase Pathway in Non-Small Cell Lung Cancer Cells Isolated from Pleural Effusions

Increased insulin sensitivity and hypoglycaemia in mice lacking the p85α subunit of phosphoinositide 3-kinase

Mfge8 promotes obesity by mediating the uptake of dietary fats and serum fatty acids

Tanshinone IIA Regulates Synaptic Plasticity in Mg 2+ -Free-Induced Epileptic Hippocampal Neurons via the PI3K/Akt Signaling Pathway

The regulatory subunits of PI3Kγ control distinct neutrophil responses

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