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Structure Basis for Directional R-loop Formation and Substrate Handover Mechanisms in Type I CRISPR-Cas System

Cell, 2017-06, Vol.170 (1), p.48-60.e11

2017

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Structural basis for promiscuous PAM recognition in type I–E Cascade from E. coli

Nature (London), 2016-02, Vol.530 (7591), p.499-503

2016

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Elucidation of the Structure and Reaction Mechanism of Sorghum Hydroxycinnamoyltransferase and Its Structural Relationship to Other Coenzyme A-Dependent Transferases and Synthases

Plant physiology (Bethesda), 2013-06, Vol.162 (2), p.640-651

2013

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Structural understanding of non-nucleoside inhibition in an elongating herpesvirus polymerase

Nature communications, 2021-05, Vol.12 (1), p.3040-3040, Article 3040

2021

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Structures of the inducer-binding domain of pentachlorophenol-degrading gene regulator PcpR from Sphingobium chlorophenolicum

International journal of molecular sciences, 2014-11, Vol.15 (11), p.20736-20752

2014

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Discovery of MK-8189, a Highly Potent and Selective PDE10A Inhibitor for the Treatment of Schizophrenia

Journal of medicinal chemistry, 2023-01, Vol.66 (2), p.1157-1171

2023

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One More Piece Down to Solve the III-A CRISPR Puzzle

Journal of molecular biology, 2015-01, Vol.427 (2), p.228-230

2015

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Allosteric Modulation of Protein Arginine Methyltransferase 5 (PRMT5)

ACS medicinal chemistry letters, 2020-09, Vol.11 (9), p.1688-1693

2020

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Discovery of Broad-Spectrum Herpes Antiviral Oxazolidinone Amide Derivatives and Their Structure–Activity Relationships

ACS medicinal chemistry letters, 2024-08, Vol.15 (8), p.1232-1241

2024

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Structural characterization of 2,6‐dichloro‐p‐hydroquinone 1,2‐dioxygenase (PcpA) from Sphingobium chlorophenolicum, a new type of aromatic ring‐cleavage enzyme

Molecular microbiology, 2013-05, Vol.88 (3), p.523-536

2013

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Structural Understanding of the Glutathione-dependent Reduction Mechanism of Glutathionyl-Hydroquinone Reductases

The Journal of biological chemistry, 2012-10, Vol.287 (43), p.35838-35848

2012

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Catalytic Mechanism of 5-Chlorohydroxyhydroquinone Dehydrochlorinase from the YCII Superfamily of Largely Unknown Function

The Journal of biological chemistry, 2013-10, Vol.288 (40), p.28447-28456

2013

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Structural and catalytic differences between two FADH(2)-dependent monooxygenases: 2,4,5-TCP 4-monooxygenase (TftD) from Burkholderia cepacia AC1100 and 2,4,6-TCP 4-monooxygenase (TcpA) from Cupriavidus necator JMP134

International journal of molecular sciences, 2012, Vol.13 (8), p.9769

2012

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Potential role of cardiac calsequestrin in the lethal arrhythmic effects of cocaine

Drug and alcohol dependence, 2013-12, Vol.133 (2), p.344-351

2013

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Structural and Catalytic Differences between Two FADH2-Dependent Monooxygenases: 2,4,5-TCP 4-Monooxygenase (TftD) from Burkholderia cepacia AC1100 and 2,4,6-TCP 4-Monooxygenase (TcpA) from Cupriavidus necator JMP134

International journal of molecular sciences, 2012-08, Vol.13 (8), p.9769-9784

2012

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Fragment-based screening approach reveals non-orthosteric pockets in the search for allosteric inhibitors of tau-tubulin kinase 1

Acta crystallographica. Section A, Foundations and advances, 2023-07, Vol.79 (a1), p.a87-a87

2023

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Elucidation of the Structure and Reaction Mechanism of Sorghum Hydroxycinnamoyltransferase and Its Structural Relationship to Other Coenzyme A-Dependent Transferases and Synthases1[C][W]

Plant physiology (Bethesda), 2013-04, Vol.162 (2), p.640-651

2013

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Structural characterization of 2,6‐dichloro‐ p ‐hydroquinone 1,2‐dioxygenase ( PcpA ) from S phingobium chlorophenolicum , a new type of aromatic ring‐cleavage enzyme

Molecular microbiology, 2013-05, Vol.88 (3), p.523-536

2013

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Structural and Catalytic Differences between Two FADH sub>2 /sub>-Dependent Monooxygenases: 2,4,5-TCP 4-Monooxygenase (TftD) from em>Burkholderia /em> em>c /em> em>epacia /em> AC1100 and 2,4,6-TCP 4-Monooxygenase (TcpA) from em>Cupriavidus /em> em>n /em> em>ecator /em> JMP134

International journal of molecular sciences, 2012-08, Vol.13 (8), p.9769-9784

2012

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Enzymatic degradation of polychlorophenols

Hayes, Robert P

2013

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Prevalence of Retinitis Pigmentosa in Maine

American journal of ophthalmology, 1984-03, Vol.97 (3), p.357-365

1984

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A 12-Year Follow-Up of a Methadone Medical Maintenance Program

The American journal on addictions, 1999, Vol.8 (4), p.293-299

1999

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The origin of accreted stellar halo populations in the Milky Way using APOGEE, Gaia , and the EAGLE simulations

Monthly notices of the Royal Astronomical Society, 2019-01, Vol.482 (3), p.3426-3442

2019

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Genetics of chronic rhinosinusitis: State of the field and directions forward

Journal of allergy and clinical immunology, 2013-04, Vol.131 (4), p.977-993.e5

2013

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Structure Basis for Directional R-loop Formation and Substrate Handover Mechanisms in Type I CRISPR-Cas System

Structural basis for promiscuous PAM recognition in type I–E Cascade from E. coli

Elucidation of the Structure and Reaction Mechanism of Sorghum Hydroxycinnamoyltransferase and Its Structural Relationship to Other Coenzyme A-Dependent Transferases and Synthases

Structural understanding of non-nucleoside inhibition in an elongating herpesvirus polymerase

Structures of the inducer-binding domain of pentachlorophenol-degrading gene regulator PcpR from Sphingobium chlorophenolicum

Discovery of MK-8189, a Highly Potent and Selective PDE10A Inhibitor for the Treatment of Schizophrenia

One More Piece Down to Solve the III-A CRISPR Puzzle

The Discovery of Two Novel Classes of 5,5-Bicyclic Nucleoside-Derived PRMT5 Inhibitors for the Treatment of Cancer

Allosteric Modulation of Protein Arginine Methyltransferase 5 (PRMT5)

Discovery of Broad-Spectrum Herpes Antiviral Oxazolidinone Amide Derivatives and Their Structure–Activity Relationships

Structural characterization of 2,6‐dichloro‐p‐hydroquinone 1,2‐dioxygenase (PcpA) from Sphingobium chlorophenolicum, a new type of aromatic ring‐cleavage enzyme

Structural Understanding of the Glutathione-dependent Reduction Mechanism of Glutathionyl-Hydroquinone Reductases

Catalytic Mechanism of 5-Chlorohydroxyhydroquinone Dehydrochlorinase from the YCII Superfamily of Largely Unknown Function

Structural and catalytic differences between two FADH(2)-dependent monooxygenases: 2,4,5-TCP 4-monooxygenase (TftD) from Burkholderia cepacia AC1100 and 2,4,6-TCP 4-monooxygenase (TcpA) from Cupriavidus necator JMP134

Potential role of cardiac calsequestrin in the lethal arrhythmic effects of cocaine

Structural and Catalytic Differences between Two FADH2-Dependent Monooxygenases: 2,4,5-TCP 4-Monooxygenase (TftD) from Burkholderia cepacia AC1100 and 2,4,6-TCP 4-Monooxygenase (TcpA) from Cupriavidus necator JMP134

Fragment-based screening approach reveals non-orthosteric pockets in the search for allosteric inhibitors of tau-tubulin kinase 1

Elucidation of the Structure and Reaction Mechanism of Sorghum Hydroxycinnamoyltransferase and Its Structural Relationship to Other Coenzyme A-Dependent Transferases and Synthases1[C][W]

Structural characterization of 2,6‐dichloro‐ p ‐hydroquinone 1,2‐dioxygenase ( PcpA ) from S phingobium chlorophenolicum , a new type of aromatic ring‐cleavage enzyme

Structural and Catalytic Differences between Two FADH sub>2 /sub>-Dependent Monooxygenases: 2,4,5-TCP 4-Monooxygenase (TftD) from em>Burkholderia /em> em>c /em> em>epacia /em> AC1100 and 2,4,6-TCP 4-Monooxygenase (TcpA) from em>Cupriavidus /em> em>n /em> em>ecator /em> JMP134

Enzymatic degradation of polychlorophenols

Prevalence of Retinitis Pigmentosa in Maine

A 12-Year Follow-Up of a Methadone Medical Maintenance Program

The origin of accreted stellar halo populations in the Milky Way using APOGEE, Gaia , and the EAGLE simulations

Genetics of chronic rhinosinusitis: State of the field and directions forward

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