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Limbic Predominant Age-Related TDP-43 Encephalopathy (LATE): Clinical and Neuropathological Associations

Journal of neuropathology and experimental neurology, 2020-03, Vol.79 (3), p.305-313

2020

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TDP-43 proteinopathy and mitochondrial abnormalities in neurodegeneration

Molecular and cellular neuroscience, 2019-10, Vol.100, p.103396-103396, Article 103396

2019

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Neurotoxic microglia promote TDP-43 proteinopathy in progranulin deficiency

Nature (London), 2020-12, Vol.588 (7838), p.459-465

2020

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Physiological functions and pathobiology of TDP‐43 and FUS/TLS proteins

Journal of neurochemistry, 2016-08, Vol.138 (S1), p.95-111

2016

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Stages of pTDP-43 pathology in amyotrophic lateral sclerosis

Annals of neurology, 2013-07, Vol.74 (1), p.20-38

2013

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RRM adjacent TARDBP mutations disrupt RNA binding and enhance TDP-43 proteinopathy

Brain (London, England : 1878), 2019-12, Vol.142 (12), p.3753-3770

2019

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RNA-binding proteins with prion-like domains in health and disease

Biochemical journal, 2017-04, Vol.474 (8), p.1417-1438

2017

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TDP-43 induces mitochondrial damage and activates the mitochondrial unfolded protein response

PLoS genetics, 2019-05, Vol.15 (5), p.e1007947-e1007947

2019

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TDP-43 pathology and memory impairment in elders without pathologic diagnoses of AD or FTLD

Neurology, 2017-02, Vol.88 (7), p.653

2017

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Microglia-mediated recovery from ALS-relevant motor neuron degeneration in a mouse model of TDP-43 proteinopathy

Nature neuroscience, 2018-03, Vol.21 (3), p.329

2018

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Distinct characteristics of limbic-predominant age-related TDP-43 encephalopathy in Lewy body disease

Acta neuropathologica, 2022-01, Vol.143 (1), p.15-31

2022

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TDP-43 Proteinopathy and Motor Neuron Disease in Chronic Traumatic Encephalopathy

Journal of neuropathology and experimental neurology, 2010-09, Vol.69 (9), p.918-929

2010

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C9orf72 poly(GR) aggregation induces TDP-43 proteinopathy

Science translational medicine, 2020-09, Vol.12 (559)

2020

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TDP-43 stage, mixed pathologies, and clinical Alzheimer's-type dementia

Brain (London, England : 1878), 2016-11, Vol.139 (11), p.2983-2993

2016

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Evaluation of TDP-43 proteinopathy and hippocampal sclerosis in relation to APOE ε4 haplotype status: a community-based cohort study

Lancet neurology, 2018-09, Vol.17 (9), p.773-781

2018

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The role of TDP-43 mislocalization in amyotrophic lateral sclerosis

Molecular neurodegeneration, 2020-08, Vol.15 (1), p.45-16, Article 45

2020

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TDP-43 protein interactome informs about perturbed canonical pathways and may help develop personalized medicine approaches for patients with TDP-43 pathology

Drug discovery today, 2023-11, Vol.28 (11), p.103769-103769, Article 103769

2023

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Neurodegenerative disease concomitant proteinopathies are prevalent, age-related and APOE4-associated

Brain (London, England : 1878), 2018-07, Vol.141 (7), p.2181-2193

2018

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Aberrant deposition of stress granule-resident proteins linked to C9orf72-associated TDP-43 proteinopathy

Molecular neurodegeneration, 2019-02, Vol.14 (1), p.9-15, Article 9

2019

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TDP-43 and RNA form amyloid-like myo-granules in regenerating muscle

Nature (London), 2018-11, Vol.563 (7732), p.508-513

2018

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Limbic-predominant age-related TDP-43 encephalopathy, ADNC pathology, and cognitive decline in aging

Neurology, 2020-10, Vol.95 (14), p.e1951

2020

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Structural Transformation of the Amyloidogenic Core Region of TDP-43 Protein Initiates Its Aggregation and Cytoplasmic Inclusion

The Journal of biological chemistry, 2013-07, Vol.288 (27), p.19614-19624

2013

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In Vivo Diagnosis of Synucleinopathies: A Comparative Study of Skin Biopsy and RT-QuIC

Neurology, 2021-05, Vol.96 (20), p.e2513

2021

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Association of Cognition and Dementia With Neuropathologic Changes of Alzheimer Disease and Other Conditions in the Oldest Old

Neurology, 2022-09, Vol.99 (10), p.e1067

2022

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Limbic Predominant Age-Related TDP-43 Encephalopathy (LATE): Clinical and Neuropathological Associations

TDP-43 proteinopathy and mitochondrial abnormalities in neurodegeneration

Limbic-predominant age-related TDP-43 encephalopathy (LATE): consensus working group report

Neurotoxic microglia promote TDP-43 proteinopathy in progranulin deficiency

Physiological functions and pathobiology of TDP‐43 and FUS/TLS proteins

Stages of pTDP-43 pathology in amyotrophic lateral sclerosis

RRM adjacent TARDBP mutations disrupt RNA binding and enhance TDP-43 proteinopathy

RNA-binding proteins with prion-like domains in health and disease

TDP-43 induces mitochondrial damage and activates the mitochondrial unfolded protein response

TDP-43 pathology and memory impairment in elders without pathologic diagnoses of AD or FTLD

Microglia-mediated recovery from ALS-relevant motor neuron degeneration in a mouse model of TDP-43 proteinopathy

Distinct characteristics of limbic-predominant age-related TDP-43 encephalopathy in Lewy body disease

TDP-43 Proteinopathy and Motor Neuron Disease in Chronic Traumatic Encephalopathy

C9orf72 poly(GR) aggregation induces TDP-43 proteinopathy

TDP-43 stage, mixed pathologies, and clinical Alzheimer's-type dementia

Evaluation of TDP-43 proteinopathy and hippocampal sclerosis in relation to APOE ε4 haplotype status: a community-based cohort study

The role of TDP-43 mislocalization in amyotrophic lateral sclerosis

TDP-43 protein interactome informs about perturbed canonical pathways and may help develop personalized medicine approaches for patients with TDP-43 pathology

Neurodegenerative disease concomitant proteinopathies are prevalent, age-related and APOE4-associated

Aberrant deposition of stress granule-resident proteins linked to C9orf72-associated TDP-43 proteinopathy

TDP-43 and RNA form amyloid-like myo-granules in regenerating muscle

Limbic-predominant age-related TDP-43 encephalopathy, ADNC pathology, and cognitive decline in aging

Structural Transformation of the Amyloidogenic Core Region of TDP-43 Protein Initiates Its Aggregation and Cytoplasmic Inclusion

In Vivo Diagnosis of Synucleinopathies: A Comparative Study of Skin Biopsy and RT-QuIC

Association of Cognition and Dementia With Neuropathologic Changes of Alzheimer Disease and Other Conditions in the Oldest Old

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