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Pembrolizumab for Early Triple-Negative Breast Cancer
The New England journal of medicine, 2020-02, Vol.382 (9), p.810-821
2020

Details

Autor(en) / Beteiligte
Titel
Pembrolizumab for Early Triple-Negative Breast Cancer
Ist Teil von
  • The New England journal of medicine, 2020-02, Vol.382 (9), p.810-821
Ort / Verlag
United States: Massachusetts Medical Society
Erscheinungsjahr
2020
Link zum Volltext
Quelle
Alma/SFX Local Collection
Beschreibungen/Notizen
  • The addition of pembrolizumab to platinum-based neoadjuvant chemotherapy significantly increased the percentage of patients with a pathological complete response among patients with locally advanced triple-negative breast cancer. Side effects of the immunotherapy were added to the usual toxic effects of chemotherapy, but most patients completed planned treatment.
Sprache
Englisch
Identifikatoren
ISSN: 0028-4793, 1533-4406
eISSN: 1533-4406
DOI: 10.1056/NEJMoa1910549
Titel-ID: cdi_swepub_primary_oai_prod_swepub_kib_ki_se_143208807
Format
–
Schlagworte
Adult, Aged, Aged, 80 and over, Antibodies, Monoclonal, Humanized - administration & dosage, Antibodies, Monoclonal, Humanized - adverse effects, Antineoplastic Combined Chemotherapy Protocols - administration & dosage, Antineoplastic Combined Chemotherapy Protocols - adverse effects, Antineoplastic Combined Chemotherapy Protocols - therapeutic use, Antitumor activity, Breast cancer, Cancer therapies, Carboplatin, Carboplatin - administration & dosage, Chemotherapy, Chemotherapy, Combination, Clinical trials, Committees, Cyclophosphamide, Cyclophosphamide - administration & dosage, Doxorubicin, Doxorubicin - administration & dosage, Epirubicin, Epirubicin - administration & dosage, Female, Hepatitis, Humans, Immunotherapy, Infections, Intention to Treat Analysis, Invasiveness, Kaplan-Meier Estimate, Medicin och hälsovetenskap, Middle Aged, Monoclonal antibodies, Neoadjuvant Therapy, Neoplasm Staging, Paclitaxel, Paclitaxel - administration & dosage, Patients, Pembrolizumab, Surgery, Targeted cancer therapy, Testing, Triple Negative Breast Neoplasms - drug therapy, Triple Negative Breast Neoplasms - mortality, Triple Negative Breast Neoplasms - pathology, Tumors

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