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Lower versus Higher Hemoglobin Threshold for Transfusion in Septic Shock
Ist Teil von
The New England journal of medicine, 2014-10, Vol.371 (15), p.1381-1391
Ort / Verlag
Waltham, MA: Massachusetts Medical Society
Erscheinungsjahr
2014
Link zum Volltext
Quelle
Electronic Journals Library
Beschreibungen/Notizen
A large Scandinavian randomized trial showed no important outcome differences between hemoglobin levels of 7 g per deciliter and 9 g per deciliter as transfusion thresholds in patients with septic shock.
Blood transfusions are frequently given to patients with septic shock.
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Some of these transfusions are given to patients who are bleeding, but many nonbleeding patients also undergo transfusion.
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The recommendations of the Surviving Sepsis Campaign regarding blood transfusion in patients with septic shock are complex and include a recommendation for transfusion to maintain a hematocrit of more than 30% in the presence of hypoperfusion in the first 6 hours.
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After that, the transfusion threshold should be a hemoglobin level of less than 7 g per deciliter, aiming at levels between 7 g and 9 g per deciliter in patients . . .