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Food is the basic need for the survival of human life. Besides, being a source of nutrients, food may also get contaminated with several toxic compounds, the most prominent among which are aflatoxins. Developing countries, especially African and Asian countries, are reported to have alarmingly higher levels of aflatoxins in foodstuff like cereals, oil seeds, dry fruits, and spices. Aflatoxins are the highly toxic secondary metabolites of fungal species that may impart several health implications if ingested beyond their maximum limits. Based on the serious health implications posed by the aflatoxins, researchers around the world are striving hard to explore both preventive and control approaches to limit the exposure of aflatoxins by the human population.