Details

Autor(en) / Beteiligte

• Tejedor, David
• Delgado-Hernández, Samuel
• Santamaría-Peláez, Blanca
• García-Tellado, Fernando

Titel

Short and modular synthesis of tetraarylsalicylaldehydes

Ist Teil von

• Chemical communications (Cambridge, England), 2020-04, Vol.56 (28), p.419-422

Ort / Verlag

England: Royal Society of Chemistry

Erscheinungsjahr

2020

Link zum Volltext

Quelle

Alma/SFX Local Collection

Beschreibungen/Notizen

• In this study, we describe a novel strategy that allows the obtention of all 15 possible substitution geometries of perarylated salicylaldehydes with total control of the regioselectivity. This strategy entitles the formation of the salicylaldehyde core via a Claisen rearrangement of propargyl vinyl ethers, followed by bromination and Pd-catalyzed aryl-aryl cross-coupling reactions. Each one of the 15 possible different substitution geometries of tetraarylated salicylaldehyde molecules is accessible through a 5-step modular strategy.