Details

Autor(en) / Beteiligte

• Mao, Zhuo-Ya
• Liu, Yi-Wen
• Ma, Rui-Jun
• Ye, Jian-Liang
• Si, Chang-Mei
• Wei, Bang-Guo
• Lin, Guo-Qiang

Titel

Divergent synthesis of N-heterocyclic 1,6-enynes through a zinc-catalyzed decarboxylative A reaction

Ist Teil von

• Chemical communications (Cambridge, England), 2019-12, Vol.55 (94), p.1417-14173

Erscheinungsjahr

2019

Link zum Volltext

Quelle

Alma/SFX Local Collection

Beschreibungen/Notizen

• A zinc-catalyzed decarboxylative A 3 reaction of cyclic amino acids, α,β-unsaturated aldehydes and terminal alkynes has been developed. A series of functionalized N-heterocyclic 1,6-enynes have been successfully obtained with excellent regioselectivities through this novel approach. In addition, the utility of this straightforward process is demonstrated by the preparation of a polycyclic nitrogen-containing heterocyclic compound. A zinc-catalyzed decarboxylative A 3 reaction of cyclic amino acids, α,β-unsaturated aldehydes and terminal alkynes has been developed.