Details

Autor(en) / Beteiligte

• Murakami, Hiroyuki
• Makita, Masanori
• Ishikawa, Tatsunori
• Yoshioka, Takanori
• Nagakita, Keina
• Shinno, Yoko
• Yoshino, Tadashi
• Maeda, Yoshinobu
• Sunami, Kazutaka

Titel

Angioimmunoblastic T-cell Lymphoma Presenting as a Methotrexate-associated Lymphoproliferative Disorder with Extreme Peripheral Blood Plasmacytosis

Ist Teil von

• Internal Medicine, 2022/09/01, Vol.61(17), pp.2655-2660

Ort / Verlag

Tokyo: The Japanese Society of Internal Medicine

Erscheinungsjahr

2022

Link zum Volltext

Quelle

Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals

Beschreibungen/Notizen

• A 74-year-old man was admitted to our hospital because of systemic lymphadenopathy, weight loss, and a fever at night that had persisted for approximately 1 month. Blood tests revealed extreme peripheral blood plasmacytosis and hypergammaglobulinemia. A lymph node biopsy showed angioimmunoblastic T-cell lymphoma (AITL). Based on the history of methotrexate (MTX) administration, the established diagnosis was MTX-associated lymphoproliferative disorder (MTX-LPD). After MTX was discontinued, the lymphadenopathy spontaneously regressed and the plasmacytosis disappeared. He had no disease progression for three years. We found that AITL as an MTX-LPD can cause plasmacytosis, and the prognosis of this disease may not be poor.