Sie befinden Sich nicht im Netzwerk der Universität Paderborn. Der Zugriff auf elektronische Ressourcen ist gegebenenfalls nur via VPN oder Shibboleth (DFN-AAI) möglich. mehr Informationen...
Laparoscopic versus open rectal resection: a 1:2 propensity score–matched analysis of oncological adequateness, short- and long-term outcomes
Ist Teil von
International journal of colorectal disease, 2021-04, Vol.36 (4), p.801-810
Ort / Verlag
Berlin/Heidelberg: Springer Berlin Heidelberg
Erscheinungsjahr
2021
Link zum Volltext
Quelle
Alma/SFX Local Collection
Beschreibungen/Notizen
Background
Laparoscopic resections for rectal cancer are routinely performed in high-volume centres. Despite short-term advantages have been demonstrated, the oncological outcomes are still debated. The aim of this study was to compare the oncological adequateness of the surgical specimen and the long-term outcomes between open (ORR) and laparoscopic (LRR) rectal resections.
Methods
Patients undergoing laparoscopic or open rectal resections from January 1, 2013, to December 31, 2019, were enrolled. A 1:2 propensity score matching was performed according to age, sex, BMI, ASA score, comorbidities, distance from the anal verge, and clinical T and N stage.
Results
Ninety-eight ORR were matched to 50 LRR. No differences were observed in terms of operative time (224.9 min. vs. 230.7;
p
= 0.567) and postoperative morbidity (18.6% vs. 20.8%;
p
= 0.744). LRR group had a significantly earlier soft oral intake (
p
< 0.001), first bowel movement (
p
< 0.001), and shorter hospital stay (
p
< 0.001). Oncological adequateness was achieved in 85 (86.7%) open and 44 (88.0%) laparoscopic resections (
p
= 0.772). Clearance of the distal (99.0% vs. 100%;
p
= 0.474) and radial margins (91.8 vs. 90.0%,
p
= 0.709), and mesorectal integrity (94.9% vs. 98.0%,
p
= 0.365) were comparable between groups. No differences in local recurrence (6.1% vs.4.0%,
p
= 0.589), 3-year overall survival (82.9% vs. 91.4%,
p
= 0.276), and disease-free survival (73.1% vs. 74.3%,
p
= 0.817) were observed.
Conclusions
LRR is associated with good postoperative results, safe oncological adequateness of the surgical specimen, and comparable survivals to open surgery.