Details

Autor(en) / Beteiligte

• Pohanka, Miroslav
• Evstigneev, Maxim P.
• Maxim P Evstigneev

Titel

D-Lactic Acid as a Metabolite: Toxicology, Diagnosis, and Detection

Ist Teil von

• BioMed research international, 2020, Vol.2020, p.3419034-9

Ort / Verlag

United States: Hindawi

Erscheinungsjahr

2020

Link zum Volltext

Quelle

Alma/SFX Local Collection

Beschreibungen/Notizen

• Two enantiomers of lactic acid exist. While L-lactic acid is a common compound of human metabolism, D-lactic acid is produced by some strains of microorganism or by some less relevant metabolic pathways. While L-lactic acid is an endogenous compound, D-lactic acid is a harmful enantiomer. Exposure to D-lactic acid can happen by various ways including contaminated food and beverages and by microbiota during some pathological states like short bowel syndrome. The exposure to D-lactic acid cannot be diagnosed because the common analytical methods are not suitable for distinguishing between the two enantiomers. In this review, pathways for D-lactic acid, pathological processes, and diagnostical and analytical methods are introduced followed by figures and tables. The current literature is summarized and discussed.