Details

Autor(en) / Beteiligte

• Inciardi, Riccardo M
• Adamo, Marianna
• Lupi, Laura
• Cani, Dario S
• Di Pasquale, Mattia
• Tomasoni, Daniela
• Italia, Leonardo
• Zaccone, Gregorio
• Tedino, Chiara
• Fabbricatore, Davide
• Curnis, Antonio
• Faggiano, Pompilio
• Gorga, Elio
• Lombardi, Carlo M
• Milesi, Giuseppe
• Vizzardi, Enrico
• Volpini, Marco
• Nodari, Savina
• Specchia, Claudia
• Maroldi, Roberto
• Bezzi, Michela
• Metra, Marco

Titel

Characteristics and outcomes of patients hospitalized for COVID-19 and cardiac disease in Northern Italy

Ist Teil von

• European heart journal, 2020-05, Vol.41 (19), p.1821-1829

Ort / Verlag

England: Oxford University Press

Erscheinungsjahr

2020

Link zum Volltext

Quelle

Oxford Journals 2020 Medicine

Beschreibungen/Notizen

• Abstract Aims To compare demographic characteristics, clinical presentation, and outcomes of patients with and without concomitant cardiac disease, hospitalized for COVID-19 in Brescia, Lombardy, Italy. Methods and results The study population includes 99 consecutive patients with COVID-19 pneumonia admitted to our hospital between 4 March and 25 March 2020. Fifty-three patients with a history of cardiac disease were compared with 46 without cardiac disease. Among cardiac patients, 40% had a history of heart failure, 36% had atrial fibrillation, and 30% had coronary artery disease. Mean age was 67 ± 12 years, and 80 (81%) patients were males. No differences were found between cardiac and non-cardiac patients except for higher values of serum creatinine, N-terminal probrain natriuretic peptide, and high sensitivity troponin T in cardiac patients. During hospitalization, 26% patients died, 15% developed thrombo-embolic events, 19% had acute respiratory distress syndrome, and 6% had septic shock. Mortality was higher in patients with cardiac disease compared with the others (36% vs. 15%, log-rank P = 0.019; relative risk 2.35; 95% confidence interval 1.08–5.09). The rate of thrombo-embolic events and septic shock during the hospitalization was also higher in cardiac patients (23% vs. 6% and 11% vs. 0%, respectively). Conclusions Hospitalized patients with concomitant cardiac disease and COVID-19 have an extremely poor prognosis compared with subjects without a history of cardiac disease, with higher mortality, thrombo-embolic events, and septic shock rates.