Details

Autor(en) / Beteiligte

• Anfossi, Simone
• Calin, George A

Titel

When non-coding is not enough

Ist Teil von

• The Journal of experimental medicine, 2020-03, Vol.217 (3)

Ort / Verlag

United States: Rockefeller University Press

Erscheinungsjahr

2020

Link zum Volltext

Quelle

EZB Electronic Journals Library

Beschreibungen/Notizen

• A new concept is emerging in the non-coding RNA (ncRNA) field: an increasing number of ncRNAs in fact codify for short peptides that have biological activities. In this issue of JEM, Wang et al. (https://doi.org/10.1084/jem.20190950) report the identification of a long ncRNA (lncRNA)-encoded 60-amino acid polypeptide that they name ASRPS, as well as its ability to inhibit angiogenesis in the deadly triple-negative breast cancer (TNBC).