Details

Autor(en) / Beteiligte

• Macdonald, Sarah E
• van Diemen, Pauline M
• Martineau, Henny
• Stevens, Mark P
• Tomley, Fiona M
• Stabler, Richard A
• Blake, Damer P
• Palmer, Guy H.

Titel

Impact of Eimeria tenella Coinfection on Campylobacter jejuni Colonization of the Chicken

Ist Teil von

• Infection and immunity, 2019-02, Vol.87 (2)

Ort / Verlag

United States: American Society for Microbiology

Erscheinungsjahr

2019

Link zum Volltext

Quelle

EZB Electronic Journals Library

Beschreibungen/Notizen

• can cause the disease coccidiosis in chickens. The direct and often detrimental impact of this parasite on chicken health, welfare, and productivity is well recognized; however, less is known about the secondary effects that infection may have on other gut pathogens. is the leading cause of human bacterial foodborne disease in many countries and has been demonstrated to exert negative effects on poultry welfare and production in some broiler lines. Previous studies have shown that concurrent infection can influence the colonization and replication of bacteria, such as and serovar Typhimurium. Through a series of coinfection experiments, this study evaluated the impact that infection had on colonization of chickens, including the influence of variations in parasite dose and sampling time after bacterial challenge. Coinfection with resulted in a significant increase in colonization in the cecum in a parasite dose-dependent manner but a significant decrease in colonization in the spleen and liver of chickens. The results were reproducible at 3 and 10 days after bacterial infection. This work highlights that not only has a direct impact on the health and well-being of chickens but can have secondary effects on important zoonotic pathogens.