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Correspondence to Ellen M Ginzler; ellen.ginzler@downstate.edu In the review entitled Engaging African-Ancestry Participants in Systemic Lupus Erythematosus Clinic Trials, Anjorin and Lipsky1 sought to (1) summarise the extensive body of literature demonstrating differences in genetics and health impact in African American (AA) patients with SLE compared with European American (EA) counterparts, and (2) describe challenges in recruiting AA for clinical trials. The healthcare professional participants in most clinical trials are the ‘usual suspects’. Because of financial constraints, investigator-generated studies are rarely large enough to result in data acceptable to the Food and Drug Administration. If it is not forthcoming from the National Institutes of Health or other agencies, perhaps the pharmaceutical industry could be induced to set up a collaborative funding source with grants to small practices or groups to set up and publicise clinical trials in minority-dominated neighbourhoods.