Details

Autor(en) / Beteiligte

• Terhaar Sive Droste, Jochim S
• Craanen, Mike E
• van der Hulst, Rene W M
• Bartelsman, Joep F
• Bezemer, Dick P
• Cappendijk, Kim R
• Meijer, Gerrit A
• Morsink, Linde M
• Snel, Pleun
• Tuynman, Hans A R E
• van Wanrooy, Roy L J
• Wesdorp, Eric I C
• Mulder, Chris J J

Titel

Colonoscopic yield of colorectal neoplasia in daily clinical practice

Ist Teil von

• World journal of gastroenterology : WJG, 2009-03, Vol.15 (9), p.1085-1092

Ort / Verlag

United States: Department of Gastroenterology and Hepatology, VU University Medical Centre, PO Box 7057, 1007 MB, Amsterdam, The Netherlands%Gastroenterology and Hepatology,Kennemer Gasthuis, 2000 AK, Haarlem, The Netherlands%Gastroenterology and Hepatology, Academic Medical Centre, 1100 DD, Amsterdam, The Netherlands%Epidemiology and Biostatistics, VU University Medical Centre, 1007 MB, Amsterdam, The Netherlands%Pathology, VU University Medical Centre, 1007 MB, Amsterdam, The Netherlands%Gastroenterology and Hepatology, Slotervaart Hospital, 1006 BK, Amsterdam, The Netherlands%Gastroenterology and Hepatology, Medical Centre Alkmaar, 1800 AM, Alkmaar, The Netherlands%Gastroenterology and Hepatology, Sint Lucas Andreas Hospital, 1061 AE, Amsterdam, The Netherlands

Erscheinungsjahr

2009

Link zum Volltext

Quelle

MEDLINE

Beschreibungen/Notizen

• AIM： To assess the prevalence and location of advanced neoplasia in patients undergoing colonoscopy, and to compare the yield per indication. METHODS： In a multicenter colonoscopy survey （n = 18 hospitals） in the Amsterdam area （Northern Holland）, data of all colonoscopies performed during a three month period in 2005 were analyzed. The location and the histological features of all colonic neoplasia were recorded. The prevalence and the distribution of advanced colorectal neoplasia and differences in yield between indication clusters were evaluated. Advanced neoplasm was defined as adenoma 〉 10 mm in size, with 〉 25% villous features or with high-grade dysplasia or cancer. RESULTS： A total of 4623 eligible patients underwent a total colonoscopy. The prevalence of advanced neoplasia was 13%, with 281 （6%） adenocarcinomas and 342 （7%） advanced adenomas. Sixty-seven percent and 33% of advanced neoplasia were located in the distal and proximal colon, respectively. Of all patients with right-sided advanced neoplasia （n = 228）, 51% had a normal distal colon, whereas 27% had a synchronous distal adenoma. Ten percent of all colonoscopies were performed in asymptomatic patients, 7% of whom had advanced neoplasia. In the respective procedure indication clusters, the prevalence of rightsided advanced neoplasia ranged from 11%-57%. CONCLUSION： One out of every 7-8 colonoscopies yielded an advanced colorectal neoplasm. Colonoscopy is warranted for the evaluation of both symptomatic and asymptomatic patients.